Have you been prescribed antidepressants to treat hot flushes or hot flashes even though you do not feel depressed? Antidepressants can be another treatment option for hot flushes.
Antidepressants for Hot Flushes
Can antidepressants be prescribed to treat hot flushes or hot flashes?
On page two in Menopause Management Options: Non-Hormonal Options – Antidepressants the (Australian) Jean Hailes for Women’s Health (JH) explain:
Note: Paroxetine and fluoxetine can reduce the effectiveness of some cancer treatment medications”.
In Hot Flashes: Diagnosis & Treatment – Treatment: Antidepressants the (United States) Mayo Clinic elaborate on:

- Venlafaxine (Effexor XR)
- Paroxetine (Paxil, Pexeva)
- Citalopram (Celexa)
- Escitalopram (Lexapro)
These medications aren’t as effective as hormone therapy for severe hot flashes, but they can be helpful to women who can’t use hormones. Possible side effects include nausea, difficulty sleeping or drowsiness, weight gain, dry mouth or sexual dysfunction”.
Hot Flushes + Depression
Do antidepressants used to help manage hot flushes also treat depression?
In Hot Flashes: What Can I Do? Non-Hormonal Medications To Treat Hot Flashes the (United States) National Institute on Aging note:
Health Care Provider
What if I would like to try an antidepressant to treat my hot flushes or hot flashes?
In Hot Flashes: What Can I Do? Non-Hormonal Medications To Treat Hot Flashes the (United States) National Institute of Aging explain:

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- 8 Myths and Truths About Menopausal Hot Flashes
- Askearlymenopause.org [Ask EM] [+ Video: What Is Early Menopause?]
- Dr Louise Newson: The Truth About the Menopause & HRT
- Find A Menopause Practitioner [United States and Other]
- Find An AMS Doctor [Australasian Menopause Society i.e. Australia and New Zealand]
- Find Your Nearest BMS Menopause Specialist [British Menopause Society]
- Hot Flashes: Non-Hormonal Medications
- Hot Flashes: Diagnosis & Treatment – Treatment: Antidepressants
- Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
- Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?]
- Menopause Map: My Personal Path Print Tools – Questions for Your Health Care Provider
- Menopause: Understanding the Changes and Finding Relief | Dr Susan Davis | The Proof Podcast EP 256
- Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
- Therapy for the Effects of Menopause
- Using Natural Therapies In the Menopause Transition – Webinar
- Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
- Video Series-2023: NAMS 2023 Nonhormone Therapies Position Statement for Bothersome Menopause Symptoms
- Video Series-2023: New FDA-Approved Nonhormone Option for the Treatment of Hot Flashes
- Videos and Podcasts: Videos – Interviews: A Simple Approach To Menopause: The Menopause Quick Six (www.MQ6.ca)
- Why Didn’t Anyone Tell Me This? Episode 3: Dr Annice Mukherjee: Your Essential Menopause Toolkit