“Hormone therapy remains first-line therapy
for management of bothersome vasomotor symptoms,
and the benefits typically outweigh the risks for…”.1
Umbrella
What may the Hormone Therapy Umbrella include?
Depending on the Source (DotS) this Umbrella may include:
- Hormone (Replacement) Therapy H(R)T
- Hormone Medicines
- Hormone Replacement Therapy (HRT)
- Hormone Therapy (HT)
- Hormones
- Medicines for Hormone Replacement Therapy
- Menopausal Hormone Therapy (MHT)
- Menopause Hormone Medicines
- Menopause Medicines
Date
What can it be important to be clear about with hormone therapy (HT) information?
It can be important to be clear about the date of all information including the date of HT information, because this information may have been updated.
Symptoms or Chronic Conditions
What can it also be important to be clear about with HT information?
It can also be important to be clear about whether HT information is about the use of HT for the management of menopausal symptoms such as hot flushes, night sweats and vaginal dryness or for the prevention of chronic conditions such as cardiovascular disease and osteoporosis.
U.S. Menopausal Hormone Therapy Labeling To Be Updated, November 2025
In the United States (U.S.) is menopausal hormone therapy labeling to be updated?
The U.S. Department of Health and Human Services press release HHS Advances Women’s Health, Removes Misleading FDA Warnings on Hormone Replacement Therapy, dated 10 November 2025, elaborates on:
Where may I find Links related to U.S. menopausal hormone therapy labeling to be updated?
Your Country may have Links similar to:
U.S. Menopausal Hormone Therapy Labeling To Be Updated, 10 November 2025
- Celebrating the Removal But Cautioning the Removal of All Warnings on HRT [10 November 2025]
- EMAS On-Demand Webinars [European Menopause and Andropause Society] [Multiply Languages]: FDA Decision on MHT Warnings – A Live EMAS Roundtable [20 November 2025]
- FDA Approves Labeling Changes To Menopausal Hormone Therapy Products [12 February 2026]
- FDA Direct: Removing Black Box Warnings for HRT (Part 1/2) [10 November 2025]
- FDA Direct: Removing Black Box Warnings for HRT (Part 2/2) [11 November 2025]
- FDA Expert Panel on Menopause and Hormone Replacement Therapy for Women [17 July 2025]
- FDA Removes Black Box Warning on HRT- What Does That Mean for the UK [11 November 2025]
- Fact Sheet: FDA Initiates Removal of “Black Box” Warnings From Menopausal Hormone Replacement Therapy Products [10 November 2025]
- HHS Advances Women’s Health, Removes Misleading FDA Warnings on Hormone Replacement Therapy [10 November 2025]
- IMS Statement: US HHS Revises Black Box Warning for Menopause Hormone Therapy [International Menopause Society] [13 November 2025]
- Menopausal Hormone Labels Should Rely on Evidence, Not Opinion [06 February 2026]
- Menopausal Hormone Therapies With Updated Prescribing Information [12 February 2026]
- News From the WHI Study. WHI Responds To FDA Removal of Black Box Warning on Hormonal Therapies [11 November 2025]
- The Removal of the Black Box on HT: Will Women’s Health Improve? [+ Video] [05 January 2026]
- Updated Labeling for Menopausal Hormone Therapy [10 November 2025]
Definition
What is hormone therapy (HT) of menopausal hormone therapy (MHT)?
DotS the definition of HT may vary.
In Glossary of Terms: Menopausal Hormone Therapy (MHT) Hormone Replacement Therapy (HRT)/ Hormone Therapy (HT), dated 22 April 2026, the Australasian Menopause Society’s (AMS) definition is:
“MHT also known as hormone replacement therapy (HRT) or hormone therapy (HT) refers to hormones prescribed to help oestrogen deficiency. This is most commonly prescribed for women around the time of menopause to relieve menopausal symptoms and to prevent osteoporosis. Women with other causes of oestrogen deficiency (such as pituitary gland problems) may also be prescribed hormone therapy”.3In Hormone Therapy the (United States) Menopause Society’s (formerly the North American Menopause Society) definition is:
“Hormone therapies (HT), sometimes mistakenly called hormone replacement therapy, are the prescription drugs used most often to treat menopause symptoms such as hot flashes and genitourinary syndrome of menopause (GSM), which includes vaginal dryness after menopause”.4
On page four of Menopause and Menopause Hormone Therapy: 2. What Is MHT? the International Menopause Society’s (IMS) Leaflet for Women for World Menopause Day 2024, the IMS’s definition is:
- Estrogen: The main hormone used in MHT. It helps reduce hot flushes, night sweats, and vaginal dryness
- Progesterone: This is given to women who still have a uterus (womb). It helps protect the womb lining from growing too much when taking estrogen”.5
5 Ws of Menopause Hormone Therapy
What is the IMS’s The 5 Ws of Menopause Hormone Therapy?
In World Menopause Day 2024: The 5 Ws of Menopause Hormone Therapy (MHT) the IMS elaborate on:
- “Who is MHT for?
- What is MHT?
- When should MHT be started and stopped?
- Why is MHT important?
- Where can you get MHT?”6
Contraceptive or Not
Is HT a contraceptive?
No. On page five in Contraception for Woman Over 40: Hormone Replacement Therapy (HRT) the (British) Women’s Health Concern (WHC) note:
“It is important to realise that HRT is not a method of contraception”.7
Effective or Not
How effective is HT?
On page one in The Menopause Society Statement on Misinformation Surrounding Hormone Therapy: Indications for the Use of Hormone Therapy, published October 2024, the Menopause Society note:
Hormone therapy is indicated for the treatment of bothersome vasomotor symptoms,
genitourinary syndrome of menopause, primary ovarian insufficiency, and prevention of bone loss and reduction of fracture risk”.8
Types
Are there different types of HT?
Yes. In HRT: Which HRT? the WHC explain:
There are over 50 different combinations of HRT currently available. Most women will make their choice whether to take HRT, and which form of HRT to take, with the help of their doctor”.9
Dose and Duration
What does the (United States) Food and Drug Administration (FDA) note about deciding to use HT?
In Menopause: Hormone Therapy – What Is Hormone Therapy for Menopause? the FDA note:
Benefits and Risks
What are the benefits and risks of HT?
In Hormone Therapy: Frequently Asked Questions – Who Should Not Use Hormone Therapy? the Menopause Society note:
“Hormone therapy is not a good choice for every woman. For some, the risks outweigh the benefits, so careful consideration with a healthcare professional is advised. In general, women who have breast cancer, uterine cancer, unexplained uterine bleeding, liver disease, a history of blood clots, and cardiovascular disease should not use hormone therapy”.11
Health Care Provider
What if I to choose to use HT?
In Treatments for Menopause: Menopausal Hormone Therapy (MHT) (Australian) Jean Hailes for Women’s Health explain:
- “Start low” (start with a low dose)
- “Go slow” (take some time to let the medicine work before increasing the dose)
- “Review often” (review your dose with your doctor once each year)”.12
Health Topics A-Z
Where may I find Health Topics A-Z related to Hormone Therapy?
In Health Topics A-Z you may find:
Health Topics A-Z
- Hormone Therapy 2022 Update for Chronic Conditions
- Hormone Therapy Benefits and Risks
- Hormone Therapy Postmenopause
- Hormone Therapy Risks
- Hormone Therapy Types
- Hormone Therapy Videos
- Hormone Therapy and Estrogen Plus Progestogen Therapy
- Hormone Therapy and Estrogen Therapy
- Hormone Therapy and Tibolone
- Menopause Videos 2026
Links
Where may I find Links related to Hormone Therapy?
Your Country may have Links similar to:
Links
This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.New or Updated
- Bleeding on HRT: What’s Normal and What’s Not [14 April 2026]
- Can You Have HRT If You Have Had A Clot? [26 February 2026]
- Can You Start HRT After 60? What the Evidence Shows [21 April 2026]
- Can’t Get Your HRT Patches? What To Do and What To Avoid [06 May 2026]
- Does HRT (Hormone Replacement Therapy) Increase Breast Cancer Risk? [08 January 2026]
- HRT, Breast Cancer and the Real Risks of Not Taking Hormones [06 April 2026]
- Pros and Cons of HRT Patches [16 December 2025]
- What Is Low-Dose Estrogen Therapy? [11 March 2026]
- Bioidentical Hormones: Are They Safer?
- Black Menopausal Women Almost 5 Times Less Likely To Be on HRT Than White Women
- Bleeding on HRT Explained | Dr Louise Newson Live
- Bleeding on HRT: What’s Normal and What’s Not
- Busting Brain Myths: The Evolving Story of Menopause Hormone Therapy and Cognitive Health
- Can HRT Stop Your Periods?
- Can You Have HRT If You Are Overweight?
- Can You Have HRT If You Have Had A Clot?
- Can You Have HRT With Uterine Fibroids
- Can You Start HRT After 60? What the Evidence Shows
- Can’t Get Your HRT Patches? What To Do and What To Avoid
- Celebrating the Removal But Cautioning the Removal of All Warnings on HRT
- Consumer Video and Podcast Series: 2024 Consumer Videos and Podcasts – Preparing for Your Menopause Health Care Visit
- Contraception for the Woman Over the Age of 40: Hormone Replacement Therapy
- Deciding About Hormone Therapy
- Deciding About Hormone Therapy Use
- Does HRT (Hormone Replacement Therapy) Increase Breast Cancer Risk?
- EMAS On-Demand Webinars [European Menopause and Andropause Society] [Multiply Languages]: FDA Decision on MHT Warnings – A Live EMAS Roundtable
- EMAS On-Demand Webinars [European Menopause and Andropause Society] [Multiply Languages]: Genitourinary Syndrome of Menopause (GSM): Diagnosis and Evidence-Based Management (EN)
- EMAS On-Demand Webinars [European Menopause and Andropause Society] [Multiply Languages]: Menopause In Cancer Survivors: Managing Complex Care
- Epilepsy, the Menopause and HRT
- FDA Direct: Removing Black Box Warnings for HRT (Part 1/2)
- FDA Direct: Removing Black Box Warnings for HRT (Part 2/2)
- FDA Removes Black Box Warning on HRT- What Does That Mean for the UK
- Fact Sheet: FDA Initiates Removal of “Black Box” Warnings From Menopausal Hormone Replacement Therapy Products
- Find A Menopause Practitioner [United States and Other]
- Find A Practitioner [Australasian Menopause Society i.e. Australia and New Zealand]
- Find Your Nearest BMS Menopause Specialist [British Menopause Society]
- From Cardiovascular Protection To Cardiovascular Risk: The Metamorphosis of Menopausal Hormone Therapy
- HHS Advances Women’s Health, Removes Misleading FDA Warnings on Hormone Replacement Therapy
- HRT
- HRT Questions Answered
- HRT Types and Doses | Dr Louise Newson
- HRT and the Likelihood of Some Medical Conditions. A Discussion Aid for GPs and Patients. Menopause: Identification and Management (NICE Guideline NG23)
- HRT – Types, Doses and Regimens
- HRT, Breast Cancer and the Real Risks of Not Taking Hormones
- HRT, Misinformation and Navigating the Menopause Media Minefield With Kaye Adams
- HRT: Benefits and Risks
- HRT: How To Find the Right Dose & Type | Dr Louise Newson
- HRT: The History
- Hormone Replacement Therapy
- Hormone Replacement Therapy (HRT)
- Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
- Hormone Replacement Therapy (HRT): Benefits and Risks of Hormone Replacement Therapy (HRT)
- Hormone Replacement Therapy (HRT): Continuous Combined Hormone Replacement Therapy (HRT) Tablets, Capsules and Patches
- Hormone Replacement Therapy (HRT): Sequential Combined Hormone Replacement Therapy (HRT) Tablets and Patches
- Hormone Replacement Therapy (HRT): Tibolone
- Hormone Replacement Therapy (HRT): Types of Hormone Replacement Therapy (HRT)
- Hormone Replacement Therapy (HRT): Vaginal Oestrogen
- Hormone Therapy
- Hormone Therapy In Postmenopausal Persons: Primary Prevention of Chronic Conditions
- Hormone Therapy: Four Things A Mayo Clinic Women’s Health Specialist Wants You To Know [+ Video Courtesy: Mayo Clinic News Network. Name Super/CG: Taryn Smith, M.D./Internal Medicine/Mayo Clinic]
- How Should You Come Off Your HRT?
- How Vaginal Hormones Can Transform the Health of Women
- IMS Statement: US HHS Revises Black Box Warning for Menopause Hormone Therapy [International Menopause Society]
- International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause
- Initiation of Hormone Therapy After Age 65 Remains Risky but Still Works for Some Women
- Joint Position Statement by the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
- Long-Term Cognitive Effects of Menopausal Hormone Therapy: Findings From the KEEPS Continuation Study
- Management of Unscheduled Bleeding on Hormone Replacement Therapy (HRT)
- Menopausal Hormone Labels Should Rely on Evidence, Not Opinion
- Menopause Hormone Therapy: Does It Cause Vaginal Bleeding?
- Menopause Care After Breast Cancer | Dr Louise Newson
- Menopause Hormone Therapy: Is It Right for You?
- Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider

- Menopause: Identification and Management [NICE Guideline]
- Menopause: Identification and Management [NICE Guideline]

- Misinformation Surrounding Hormone Therapy
- Navigating Menopause Care Resource Guide

- New Estradot Conti HRT Available
- News From the WHI Study. WHI Responds To FDA Removal of Black Box Warning on Hormonal Therapies
- Online Events [International Menopause Society]: Past Webinars – 2025: The Burn, the Itch, the Pain, the Urge: GSM In Women
- Practical HRT Tips | Dr Louise Newson
- Progestin Sensitivity / Progesterone Intolerance
- Pros and Cons of HRT Patches
- Slynd As Endometrial Protection
- Testosterone and Why the UK Is Falling Behind
- The 2023 Practitioner’s Toolkit for Managing Menopause
- The Debate About Hormone Replacement Therapy During Menopause In MS: Rhonda R. Voskuhl, MD
- The Menopause Society Statement on Misinformation Surrounding Hormone Therapy

- The Removal of the Black Box on HT: Will Women’s Health Improve? [+ Video]
- The Role of Topical Vaginal Oestrogen
- The Women’s Health Initiative Randomized Trials and Clinical Practice
- The Women’s Health Initiative Trials: Clinical Messages
- Understanding Hormone Therapy for Menopausal Symptoms
- Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions
- Update – Subcutaneous Hormone Implant Therapy
- Updated 2024 NICE Menopause Guidance Summary
- Updated Labeling for Menopausal Hormone Therapy
- Video: Hormone Therapy Protects Bone, Heart, Brain Health During Menopause
- Videos & Podcasts: Videos – Menopause and Hormone Therapy: Current Perspectives and Controversies
- What Are the Benefits and Risks of HRT? [Videos]
- What Is Low-Dose Estrogen Therapy?
- What Types of Vaginal Oestrogens Are There?
- When MS Meets Menopause: Is It Time To Rethink HRT?
- Why Understanding Your Hormones Changes Everything
- Why You Get An Itch or Thrush on Vaginal Estrogen and What To Do About It
- World Menopause Day 2024: Leaflet for Women – Menopause and Menopause Hormone Therapy [Multiply Languages]
- World Menopause Day 2024: Poster for Women – The 5 Ws of Menopause Hormone Therapy (MHT)
- World Menopause Day 2024: The IMS White Paper: Menopause and MHT In 2024: Addressing the Key Controversies [Multiply Languages]
- Your Daily Dose: Let’s Unpack Menopause
Sources
Where may I find the Sources quoted?
You may find the Sources quoted at:
Sources
- The Menopause Society Statement on Misinformation Surrounding Hormone Therapy: Indications for the Use of Hormone Therapy. 2024:1. Menopause Society https://menopause.org/wp-content/uploads/2024/09/TMS-statement-on-HT-Misinformation.pdf Accessed: 07 May 2026
- HHS Advances Women’s Health, Removes Misleading FDA Warnings on Hormone Replacement Therapy. 10 November 2025. U.S. Department of Health and Human Services https://www.hhs.gov/press-room/hhs-advances-womens-health-removes-misleading-fda-warnings-hormone-replacement-therapy.html Accessed: 07 May 2026
- Glossary of Terms: Menopausal Hormone Therapy (MHT) Hormone Replacement Therapy (HRT)/ Hormone Therapy (HT). 22 April 2026. Australasian Menopause Society’s https://hub.menopause.org.au/Play?pId=b474d931-428c-4cf7-a80a-74ff4287b33d Accessed: 07 May 2026
- Hormone Therapy. Menopause Society https://menopause.org/patient-education/menopause-topics/hormone-therapy Accessed: 07 May 2026
- Menopause and Menopause Hormone Therapy: 2. What Is MHT? 2024:4. International Menopause Society https://www.imsociety.org/wp-content/uploads/2024/10/2024-WMD-Leaflet_English.pdf Accessed: 07 May 2026
- World Menopause Day 2024. 2024. International Menopause Society https://www.imsociety.org/wp-content/uploads/2024/10/2024-WMD-Leaflet_English.pdf Accessed: 07 May 2026
- Contraception for Women Over the Age of 40: Hormone Replacement Therapy. Reviewed: December 2025:5. British Women’s Health Concern https://www.womens-health-concern.org/wp-content/uploads/2025/12/04-NEW-WHC-FACTSHEET-Contraception-for-women-over-the-age-of-40-DEC2025-A.pdf Accessed: 07 May 2026
- The Menopause Society. October 2024:1. The Menopause Society Statement on Misinformation Surrounding Hormone Therapy: Indications for the Use of Hormone Therapy https://menopause.org/wp-content/uploads/2024/09/TMS-statement-on-HT-Misinformation.pdf Accessed: 07 May 2026
- HRT: Which HRT? Publication Date: November 2021. Women’s Health Concern https://www.womens-health-concern.org/wp-content/uploads/2022/12/09-WHC-FACTSHEET-HRT-NOV2022-B.pdf Accessed: 07 May 2026
- Menopause: Hormone Therapy – What Is Hormone Therapy for Menopause? Content Current As of: 14 December 2023. Food and Drug Administration https://www.fda.gov/ForConsumers/ByAudience/ForWomen/WomensHealthTopics/ucm117978.htm Accessed: 07 May 2026
- Hormone Therapy: Frequently Asked Questions – Who Should Not Use Hormone Therapy? 2024. Menopause Society https://menopause.org/patient-education/menopause-topics/hormone-therapy Accessed: 07 May 2026
- Treatments for Menopause: Menopausal Hormone Therapy (MHT). Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-topics/menopause/treatments-for-menopause/ Accessed: 07 May 2026

