Hormone Therapy and Heart Disease

Hormone Therapy and Heart Disease

“If women start HRT around the time of menopause,
the risk is very small and there appear to be
cardiovascular and bone protective benefits”.1

Umbrella

What may the Hormone Therapy and Heart Disease Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Cardiovascular Disease
  • Coronary Heart Disease
  • Heart Disease
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Ischemic Heart Disease
  • Menopausal Hormone Therapy (MHT)

Cardiovascular Diseases

What are cardiovascular diseases (CVDs)?

DotS the definition of CVDs may vary. The World Health Organization’s definition is:

“CVDs are a group of disorders of the heart and blood vessels and include coronary heart disease, cerebrovascular disease, rheumatic heart disease and other conditions”.2

Heart Disease

What is heart disease?

DotS the definition of heart disease may vary. The (United States) Centers for Disease Control and Prevention’s definition is:

“The term “heart disease” refers to several types of heart conditions. The most common type of heart disease in the United States is coronary artery disease (CAD). CAD affects the blood flow to the heart. Decreased blood flow can cause a heart attack”.3

Type

Hormone Therapy and Heart DiseaseHormone Therapy and heart Disease What can it be important to be clear about with hormone therapy (HT) and heart disease risk information?

It can be important to be clear about the type of HT and whether heart disease risk information is about – Estrogen Plus Progestogen HT or Estrogen-Alone HT.

Younger Than Age 60 or Not

What can it also be important to be clear about with HT and heart disease risk information?

It can also be important to be clear about whether HT and heart disease risk information is about women “younger than age 60 years or within 10 years of menopause” or not.

Younger Than Age 60

For women younger than age 60 or within 10 years of menopause, what is the association between HT and heart disease risk?

On page one in Deciding About Hormone Therapy Use: Potential Risks, published February 2025, the Menopause Society (formerly the North American Menopause Society) explain:

“Some studies suggest that HT might be good for your heart if you start before age 60 or within 10 years of menopause”.4

After Age 60

For women after age 60 or further than 10 years from menopause, what is the association between HT and heart disease risk?

On page three in Hormone Replacement Therapy (HRT): Benefits and Risks – HRT Today – The Key Points, reviewed July 2026, the (British) Women’s Health Concern explain:

“If women start HRT around the time of menopause, the risk is very small and there appear to be cardiovascular and bone protective benefits. It is not usually appropriate for women over 60 to be starting HRT but as the WHI study showed, women initiating it over 60 years of age do not seem to be at increased risk of cardiovascular events or mortality”.5

Health Care Provider

If I choose to use HT what are my risks of heart disease?

In Hormone Therapy: Is It Right for You? The Bottom Line: Hormone Therapy Isn’t All Good or All Bad the (United States) Mayo Clinic explain:

“To find out if menopause hormone therapy is a good option for you, talk to your healthcare professional about your symptoms and health risks. You also can ask your healthcare professional for help finding a certified menopause expert. Or check with a professional organization such as The Menopause Society. Be sure to keep the conversation going throughout menopause.

As researchers learn more about menopause hormone therapy and other menopause treatments, recommendations may change. But if you have menopause symptoms that disrupt your sleep or get in the way of daily life, it’s worthwhile to talk to your healthcare professional about treatment options”.6

Health Topics A-Z

Where may I find Health Topics A-Z related to Hormone Therapy and Heart Disease?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

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New or Updated

  1. BMS TV: Coronary Heart Disease (CHD)
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  3. Bioidentical Hormones: Are They Safer?
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  5. Can You Take Hormone Replacement Therapy If You Have Heart Disease?
  6. Consumer Video and Podcast Series: 2023 Consumer Videos and Podcasts – Menopause and Heart Disease
  7. Consumer Video and Podcast Series: 2024 Consumer Videos and Podcasts – Preparing for Your Menopause Healthcare Visit
  8. Coronary Heart Disease [+ Know the Difference]
    Hormone Therapy and Heart Disease
  9. Deciding About Hormone Therapy
  10. Deciding About Hormone Therapy Use
  11. Deep Vein Thrombosis
  12. FDA Grand Rounds: FDA Menopausal Hormone Therapy (MHT) Labeling: Historical Context & Recent Changes
  13. Find A Member [Australasian Menopause Society i.e. Australia and New Zealand]
  14. Find A Menopause Practitioner [United States and Other]
  15. Find Your Nearest BMS Menopause Specialist [British Menopause Society]
  16. Finding the Right Hormone Treatments (HRT): Types, Doses and What Works
  17. From Cardiovascular Protection To Cardiovascular Risk: The Metamorphosis of Menopausal Hormone Therapy
  18. Goredforwomen.org [Go Red for Women, American Heart Association United States]Heart Disease and Menopause Heart Disease and Menopause
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  21. HRT – Types, Doses and Regimens
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  23. Handling Hot Flushes and Night Sweats| Dr Louise Newson
  24. Heart Disease, Family Health History, and Familial Hypercholesterolemia
  25. Heart Health for Women [+ Videos]
  26. Heart Health for Women [+ Videos]: Download Heart Health for Women Fact Sheet In Other Languages
  27. Heart Health, Hormones and Menopause With Dr Jeremy London | Dr Louise Newson Podcast
  28. Hormone Replacement Therapy (HRT)
  29. Hormone Replacement Therapy (HRT): A Summary
  30. Hormone Replacement Therapy (HRT): Alternatives To Hormone Replacement Therapy (HRT)
  31. Hormone Replacement Therapy (HRT): Benefits and Risks 
  32. Hormone Therapy
  33. Hormone Therapy In Postmenopausal Persons: Primary Prevention of Chronic Conditions
  34. Hormone Therapy: Is It Right for You?
  35. How To Find Relief for Hot Flashes At Night
  36. International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause
  37. Is It Too Late To Start HRT?
  38. Know Your Numbers They Could Just Save Your Life
  39. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video] [Other Languages and Formats]
  40. Life’s Essential 8
  41. Listen To Your Heart: Women and Heart Disease
  42. Management of Menopause for Women With Cardiovascular Disease
  43. Mayo Clinic Minute: Menopause and the Heart Connection [+ Video Courtesy: Mayo Clinic News Network]
  44. Menopausal Symptom Treatments
  45. Menopause
  46. Menopause
  47. Menopause Management for Women With Heart Disease
  48. Menopause and Cardiovascular Disease and Using HRT To Treat Menopause Symptoms
  49. Menopause and Heart Disease
  50. Menopause and Heart Disease
  51. Menopause and Your Heart: HRT Benefit or Risk To Your Heart?
  52. Menopause: Identification and Management [NICE Guideline]
  53. Menopause: Identification and Management [NICE Guideline]
    Hormone Therapy and Heart Disease
  54. National Center for Complementary and Integrative Health: Cardiovascular Disease
  55. National Center for Complementary and Integrative Health: Chelation for Coronary Heart Disease: What You Need To Know
  56. National Center for Complementary and Integrative Health: How Safe Is This Product or Practice?
  57. Online Events International Menopause Society]: IMS Partnership Symposia Series – Evaluating High-Risk Patients In Menopause At Risk of Cardiovascular Disease (CVD)
  58. Online Events [International Menopause Society]: IMS Partnership Symposia Series – What’s Hot? Options for Treatment of Hot Flushes 2025
  59. Online Events [International Menopause Society]: Past Webinars – 2025: Lifestyle Medicine
  60. Online Events [International Menopause Society]: Past Webinars – 2026: New IMS Recommendations: Evidence-Based Management of Vasomotor Symptoms
  61. Online Events [International Menopause Society]: Past Webinars – 2026: New IMS Recommendations – Lifestyle, Diet, Exercise
  62. Online Events [International Menopause Society]: Past Webinars – 2026: New IMS Recommendations – Midlife Body Changes
  63. Rethinking Menopausal Hormone Therapy: For Whom, What, When, and How Long?
  64. Risks and Benefits of MHT
  65. The 2023 Practitioner’s Toolkit for Managing Menopause
  66. The Benefits and Risks of Menopause Hormone Therapy for the Cardiovascular System In Postmenopausal Women: A Systematic Review and Meta-Analysis
  67. The Menopause Society Show: Menopause & Cardiovascular Health
  68. The Women’s Health Initiative Trials: Clinical Messages
  69. Videos and Podcasts: Videos – Heart Disease, Risk Factors of Developing Heart Disease, and Can I Take Hormones?
  70. Video: Hormone Therapy Protects Bone, Heart, Brain Health During Menopause
  71. What Is Cardiovascular Disease?
  72. What Is Cardiovascular Disease?
  73. ‘What’s Normal Has Changed’: Navigating Menopausal Hormone Therapy As CVD Risk Grows
  74. Women & CVD
  75. World Heart Day [29 September]

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Hormone Replacement Therapy (HRT): Benefits and Risks – HRT Today – The Key Points. Reviewed: July 2026:3.Women’s Health Concern https://www.womens-health-concern.org/wp-content/uploads/2026/07/11-NEW-WHC-FACTSHEET-HRT-BenefitsRisks-JULY2026-A.pdf Accessed: 09 October 2026
  2. Cardiovascular Diseases. World Health Organization https://www.who.int/health-topics/cardiovascular-diseases#tab=tab_1 Accessed: 09 October 2026
  3. Heart Disease: About Heart Disease. 15 May 2024. Centers for Disease Control and Prevention https://www.cdc.gov/heart-disease/about/ Accessed: 09 October 2026
  4. Deciding About Hormone Therapy Use: Potential Risks. 2025:1. Menopause Society https://menopause.org/wp-content/uploads/default-document-library/MenoNote-Deciding-About-HT-2025.pdf Accessed: 09 October 2026
  5. Hormone Replacement Therapy (HRT): Benefits and Risks – HRT Today – The Key Points. Reviewed: July 2026:3.Women’s Health Concern https://www.womens-health-concern.org/wp-content/uploads/2026/07/11-NEW-WHC-FACTSHEET-HRT-BenefitsRisks-JULY2026-A.pdf Accessed: 09 October 2026
  6. Hormone Therapy: Is It Right for You? The Bottom Line: Hormone Therapy Isn’t All Good or All Bad. 18 April 2025. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/menopause/in-depth/hormone-therapy/art-20046372 Accessed: 09 October 2026
Topic Last Updated: 09 October 2026 – Topic Last Reviewed: 09 October 2026

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