“If you do not have a uterus, you can take estrogen alone, without a progestogen”.1

Umbrella
What may the Hormone Therapy and Estrogen Therapy Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Estrogen Alone
  • Estrogen Therapy (ET)
  • Estrogen-Alone HRT/MHT
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Oestrogen-Only HRT
  • Oestrogen-Only Therapy/Oestrogen Only Therapy
  • Systemic ET

No UterusHormone Therapy and Estrogen Therapy

Who may choose to use estrogen therapy (ET)?

One of the points of consensus in the Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT – endorsed by seven menopause-related organizations – published online 20 June 2016, is:

  • “Estrogen as a single systemic agent is appropriate in women after hysterectomy…”.2

On page two in Deciding About Hormone Therapy Use: Estrogen Alone or Estrogen Plus Progestogen the North American Menopause Society in June 2017 note:

  • “If you do not have a uterus, you can take estrogen alone, without a progestogen”.3

In Oestrogen Only Menopausal Hormone Therapy: Key Points the Australasian Menopause Society (AMS) note about menopausal hormone therapy (MHT)/hormone replacement therapy (HRT):

  • “After hysterectomy MHT/HRT only needs to contain oestrogen”.4

In Hormone Replacement Therapy (HRT): Types – HRT Hormones the (United Kingdom) NHS (National Health Service) also note:

“Oestrogen-only HRT is usually only recommended for women who have had their womb removed during a hysterectomy”.5

Health Care Provider

If I choose to use ET what are my risks?

Different women who choose to use ET can have different risks. It may therefore be in your best interest to choose to talk to your health care provider about this.

One of the points of consensus about menopausal hormone therapy (MHT) in the Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT is:

  • “The option of MHT is an individual decision in terms of quality of life and health priorities as well as personal risk factors such as age, time since menopause and the risk of VTE, stroke, ischemic heart disease and breast cancer. MHT should not be recommended without a clear indication for its use”.6

What is VTE?

VTE can be an abbreviation for Venous Thromboembolism.

In Menopause FAQs: Hormone Therapy – Q. What Is Hormone Therapy? the NAMS also note:

“You should discuss your individual risks and preferences with your healthcare team to determine whether hormone therapy or alternatives, including FDA-approved nonhormonal therapies, are right for you”.7

What is FDA?

FDA can be an abbreviation for the (United States) Food and Drug Administration.

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Sources

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You may find the Sources at:

Sources

  1. Deciding About Hormone Therapy Use: Estrogen Alone or Estrogen Plus Progestogen. 2017:2. North American Menopause Society https://www.menopause.org/docs/default-source/for-women/menonote-deciding-about-ht-2017.pdf Accessed: 06 July 2020
  2. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT. Climacteric, 2016;19:4:314 https://www.imsociety.org/manage/images/pdf/ba6379e868044bec13015ac2b84f2753.pdf Accessed: 06 July 2020
  3. Deciding About Hormone Therapy Use: Estrogen Alone or Estrogen Plus Progestogen. 2017:2. North American Menopause Society https://www.menopause.org/docs/default-source/for-women/menonote-deciding-about-ht-2017.pdf Accessed: 06 July 2020
  4. Oestrogen Only Menopausal Hormone Therapy: Key Points. Content Updated February 2017. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/552-oestrogen-only-mht Accessed: 06 July 2020
  5. Hormone Replacement Therapy (HRT): Types – HRT Hormones. Page Last Reviewed: 09 September 2019. NHS (National Health Service) https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/types/#hrt-hormones Accessed: 06 July 2020
  6. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT. Climacteric, 2016;19:4:314 https://www.imsociety.org/manage/images/pdf/ba6379e868044bec13015ac2b84f2753.pdf Accessed: 06 July 2020
  7. Menopause FAQs: Hormone Therapy – Q. What Is Hormone Therapy? North American Menopause Society https://www.menopause.org/for-women/menopause-faqs-hormone-therapy-for-menopause-symptoms Accessed: 06 July 2020

Topic Last Updated: 23 August 2020 – Topic Last Reviewed: 06 July 2020
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