Hormone Therapy and Estrogen Plus Progestogen Therapy

“Because estrogen stimulates the lining of the uterus, women with a uterus need to take an additional hormone, progestogen, to protect the uterus”.1

Umbrella

What may the Hormone Therapy and Estrogen Plus Progestogen Therapy Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Combination Estrogen and Progestin Medicines
  • Combination HT/HRT
  • Combination Hormone Replacement/Hormone Therapy
  • Combined Hormonal Therapy
  • Combined Hormone Replacement Therapy
  • Estrogen Plus Progestogen
  • Estrogen With Progestogen Therapy
  • Estrogen and Progestin (Hormone Replacement Therapy)
  • Estrogen-Progestogen Therapy (EPT)
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Oestrogen and Progesterone Therapy

Hormone Therapy

What is hormone therapy (HT) or menopausal hormone therapy (MHT) ?

DotS the definition of HT or MHT may vary. In Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Is MHT? the (Australian) Jean Hailes for Women’s Health’s definition is:

“MHT is the medical replacement of female hormones oestrogen and progesterone, and sometimes testosterone”.2

Progesterone

What is progesterone?

DotS the definition of progesterone may vary. In Glossary of Terms the Australasian Menopause Society’s (AMS) definition is:

“Progesterone is the ovarian hormone produced by the corpus luteum which prepares the endometrium for implantation of the fertilized egg”.3

Progestogen

What is progestogen?

DotS the definition of progestogen may vary. The AMS’s definition is:

“Progestogen is a hormone which can be natural or synthetic but has a similar effect on a woman’s body as progesterone”.4

Progestin

What is progestin?

DotS the definition of progestin may vary. The AMS’s definition is:

“Progestin is a synthetic hormone which has the actions of progesterone”.5

UterusHormone Therapy and Estrogen Plus Progestogen Therapy

Who can choose to use estrogen plus progestogen hormone therapy (HT)?

On page one in Deciding About Hormone Therapy Use, published July 2022, the North American Menopause Society elaborate on:

“Hormone therapy involves taking estrogen in doses high enough to raise the level of estrogen in your blood in order to treat hot flashes and other symptoms. Because estrogen stimulates the lining of the uterus, women with a uterus need to take an additional hormone, progestogen, to protect the uterus”.6

In Menopause Management Options: Menopausal Hormone Therapy (MHT) – Types of MHT: Oestrogen and Progesterone Therapy the JH explain:

“If you haven’t had a hysterectomy, oestrogen and progesterone are used together, as progesterone reduces the risk of endometrial cancer (cancer of the uterus).

Other combinations of oestrogen and progestogen (including progesterone and other progesterone-like hormones) may also be recommended”.7

Health Care Provider

If I choose to use estrogen plus progestogen (EPT) what are my risks?

Different women who choose to use EPT can have different risks. It may therefore be in your best interest to also choose to talk to your health care provider about this.

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause first published online 10 June 2022, one of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use”.8

Health Topics A-Z

Where may I find Health Topics A-Z related to Hormone Therapy and Estrogen Plus Progestogen Therapy?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

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Links

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New or Updated

  1. 8 Myths and Truths About Menopausal Hot Flashes
  2. ACOG Explains: Managing Menopause Symptoms [American College of Obstetricians and Gynecologists] [October 2023]
  3. Askearlymenopause.org [Ask EM] [+ Video: What Is Early Menopause?]
  4. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  5. BMS TV: HRT and Bleeding
  6. BMS TV: HRT and Breast Cancer: Overall Risks and Benefits
  7. BMS TV: HRT and the Risk of Breast Cancer
  8. BMS TV: Hormone Replacement Therapy (HRT)
  9. BMS TV: Progestogens
  10. Bioidentical Hormones: Are They Safer?
  11. Consumer Video and Podcast Series: 2022 Consumer Videos and Podcasts – Hormone Therapy: Understanding the Risks and Benefits
  12. Consumer Video and Podcast Series: 2023 Consumer Videos and Podcasts – Lifestyle Modification and Prevention of Breast Cancer
  13. Consumer Video and Podcast Series: 2023 Consumer Videos and Podcasts – Premature and Early Menopause
  14. Consumer Video and Podcast Series: 2024 Consumer Videos and Podcasts – Preparing for Your Menopause Health Care Visit
  15. Deciding About Hormone Therapy
  16. Deciding About Hormone Therapy Use
  17. EMAS On-Demand Webinars [European Menopause and Andropause Society] [Multiply Languages]: Personalized Oral Combined MHT and Long-Term Effects: How To Choose According To the Patient’s Needs [Multiply Languages]
  18. Estrogen: What It Does and 5 Benefits
  19. FAQs: Hormone Therapy for Menopause
  20. Guidance on Menopausal Hormone Therapy
  21. HRT
  22. HRT – Types, Doses and Regimens
  23. HRT: Benefits and Risks
  24. Hormone Replacement Therapy (HRT)
  25. Hormone Replacement Therapy (HRT) With Dr Nicky Peel & Prof. David Armstrong
  26. Hormone Replacement Therapy (HRT): Benefits and Risks of Hormone Replacement Therapy (HRT)
  27. Hormone Replacement Therapy (HRT): Continuous Combined Hormone Replacement Therapy (HRT) Tablets, Capsules and Patches
  28. Hormone Replacement Therapy (HRT): Continuous Combined Hormone Replacement Therapy (HRT) Tablets, Capsules and Patches – Side Effects of Continuous Combined HRT
  29. Hormone Replacement Therapy (HRT): Oestrogen Tablets, Patches, Gel and Spray
  30. Hormone Replacement Therapy (HRT): Sequential Combined Hormone Replacement Therapy (HRT) Tablets and Patches
  31. Hormone Replacement Therapy (HRT): Sequential Combined Hormone Replacement Therapy (HRT) Tablets and Patches – Side Effects of Sequential Hormone Replacement Therapy (HRT)
  32. Hormone Replacement Therapy (HRT): Types of Hormone Replacement Therapy (HRT)
  33. Hormone Replacement Therapy (HRT): Utrogestan (Micronised Progesterone)
  34. Hormone Replacement Therapy (HRT): Utrogestan (Microsecond Progesterone) – Side Effects of Utrogestan
  35. Hormone Therapy: Is It Right for You?
  36. Hot Flashes
  37. Hot Flashes
  38. Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
  39. Hot Flashes? Night Sweats? Progesterone Can Help Reduce Symptoms of Menopause
  40. How To Find Relief for Hot Flashes At Night
  41. I Forgot To Ask the Doctor – E9: The Menopause: Can Every Woman That Wants It Have HRT?
  42. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  43. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?] [Other Languages and Formats]
  44. Managing Your Symptoms
  45. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video]
  46. Menopausal Hormone Therapy
  47. Menopausal Hormone Therapy and Breast Cancer Risk
  48. Menopausal Hormone Therapy and Venous Thromboembolism
  49. Menopausal Hormone Therapy, Heart Disease and Stroke
  50. Menopause
  51. Menopause
  52. Menopause
  53. Menopause Definitions
  54. Menopause Hormone Therapy: Does It Cause Vaginal Bleeding?
  55. Menopause Management Options
  56. Menopause Management: Menopausal Hormone Therapy (MHT)
  57. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  58. Menopause Map: Downloadable Resources – Stages of Menopause: Medication Tracker
    Hormone Therapy and Estrogen Plus Progestogen Therapy
  59. Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
  60. Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
  61. Menopause Patient Information [Videos] 4. The Different Types of HRT
  62. Menopause Preparedness Toolkit Video Series: Treating Vasomotor Symptoms of Menopause
  63. Menopause Management Options
  64. Menopause Symptoms and Relief
  65. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
  66. Menopause Treatments: What Works, What Doesn’t
  67. Menopause What Are the Symptoms?
  68. Menopause and HRT
  69. Menopause and HRT: Fact and Fiction
  70. Menopause: Diagnosis & Treatment
  71. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  72. Menopause: Understanding the Changes and Finding Relief | Dr Susan Davis | The Proof Podcast EP 256
  73. Mymenoplan.org [My Menoplan, United States]
  74. Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
  75. Navigating Menopause: Honest Answers To All Your Questions [+ Video: What To Expect in Menopause]
  76. Progesterone Intolerance | Dr Louise Newson [Video]
  77. Risks and Benefits of MHT
  78. The 2023 Practitioner’s Toolkit for Managing Menopause
  79. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement
  80. The Truth About Menopause Supplements | Dr Sarah Berry
  81. Therapy for the Effects of Menopause
  82. Tips To Help Manage Menopause Symptoms
  83. Types of Hormone Therapy
  84. Videos and Podcasts: Videos – Interviews: A Simple Approach To Menopause: The Menopause Quick Six (www.MQ6.ca)
  85. Videos and Podcasts: Videos – Interviews: Heart Disease, Risk Factors of Developing Heart Disease, and Can I Take Hormones?
  86. Videos and Podcasts: Videos – Interviews: The Women’s Health Initiative – What Can We Believe?
  87. Webinars: Previous – Hormones and Stroke: An Update on Treatment and Risk [20 February 2024]
  88. Webinars: Previous – Progestogen, Progestin, Progesterone: Why All the Confusion?
  89. What Are the Benefits and Risks of HRT?
  90. What Doctors Wish Patients Knew About Menopause
  91. What Everyone Should Know About Menopause Symptoms [Video]
  92. Why Didn’t Anyone Tell Me This? Episode 3: Dr Annice Mukherjee: Your Essential Menopause Toolkit

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Deciding About Hormone Therapy Use. 2022:1. Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 12 September 2024
  2. Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Is MHT? Last Updated: 03 September 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 12 September 2024
  3. Glossary of Terms: Progesterone. Content Updated: February 2022. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/381-glossary-of-terms Accessed: 12 September 2024
  4. Glossary of Terms: Progestogen. Content Updated: February 2022. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/381-glossary-of-terms Accessed: 12 September 2024
  5. Glossary of Terms: Progestin. Content Updated: February 2022. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/381-glossary-of-terms Accessed: 12 September 2024
  6. Deciding About Hormone Therapy Use. 2022:1. Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 12 September 2024
  7. Menopause Management Options: Menopausal Hormone Therapy (MHT) – Types of MHT: Oestrogen and  Progesterone Therapy. Last Updated: 03 September 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 12 September 2024
  8. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:3-4. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 12 September 2024
Topic Last Updated: 12 September 2024 – Topic Last Reviewed: 12 September 2024

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