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Empty Nest Syndrome

April 6, 2026
Health Topics

Empty Nest Syndrome

“Empty nest syndrome isn’t a clinical diagnosis. Instead,
it’s a phenomenon where parents experience feelings of
sadness and loss when the last child leaves home”.1

Umbrella

What may the Empty Nest Syndrome Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Empty Nest Syndrome
  • Midlife Empty Nest Syndrome

Definition

What is empty nest syndrome?

Depending on the Source (DotS) the definition of empty nest syndrome may vary. In 4 Tips for Enjoying Your Empty Nest the (United States) Mayo Clinic’s definition is:

“Empty nest syndrome isn’t a clinical diagnosis. Instead, it’s a phenomenon where parents experience feelings of sadness and loss when the last child leaves home”.2

In How To Cope With Empty Nest Syndrome: What Is Empty Nest Syndrome? dated 16 August 2024, the (United States) Cleveland Clinic’s definition is:

“Empty nest syndrome is the complicated tangle of feelings parents experience when their children move out of the family home and begin their adult lives. It’s not a diagnosable mental health issue, but that doesn’t mean it isn’t real. All that emotional upheaval and anticipatory grief can have a big impact, from prompting a broader existential crisis to causing physical symptoms or catastrophic thinking”.3

Age Group

What age group is empty nest syndrome associated with?

In Empty Nest Syndrome: What Age Group Is Empty Nest Associated With? the (United States) PsychCentral elaborate on:

“Parents and caregivers in the United States are usually between 40 and 60 years old when they begin empty nesting. Life events and stages, such as second marriages, late childbearing, or being grandparent caregivers, can affect when the syndrome starts.

Empty nest syndrome age may also be different in cultures and countries with varying child care arrangements”.4

Symptoms

What may be symptoms of empty nest syndrome?

In How To Cope With Empty Nest Syndrome: Symptoms the Cleveland Clinic explain:

Empty Nest Syndrome“Again, empty nest syndrome isn’t a diagnosable psychiatric condition, but Dr. Borland says people experiencing it tend to experience some or all of the following feelings:

  • Fear
  • Grief
  • Sadness
  • Guilt
  • Stress
  • Loneliness
  • Irritability
  • Emptiness
  • Powerlessness
  • Rejection
  • Apathy
  • Hopelessness

If these sound like symptoms of anxiety and depression, it’s because they are. Think of empty nest syndrome as a milder, situational version of these conditions. If these feelings intensify or seriously impact your daily life, you may be dealing with something more serious”.5

Menopause

Is there an association between menopause and mental health?

In Menopause and Mental Health: Mental Health Symptoms Related To Menopause the Australasian Menopause Society note:

“Some of the common physical, memory and thinking symptoms related to menopause (hot flushes, night sweats, sleep and sexual disturbances, weight changes and “brain fog”) can complicate and overlap with mental health symptoms.

Another complicating factor is stress related to life circumstances. Feeling stress is common during middle age as personal and environmental changes take place. This can have a strong effect on mood in some women. Life circumstances that can impact mental health include:

  • Caring for children
  • Empty Nest SyndromeCaring for elderly parents
  • Career changes
  • Relationship changes
  • Ageing
  • Body changes
  • Illness.

The menopause transition is an ideal time to take stock of all aspects of your health and consider lifestyle and other changes so that you can live the healthiest possible lifestyle”.6

Coping

How can parents cope with empty nest syndrome?

In 4 Tips for Enjoying Your Empty Nest: Advice for the Transition the Mayo Clinic elaborate on:

“Here are a few tips if you’re experiencing feelings of loss due to empty nest syndrome:

  • Accept the timing…
  • Keep in touch…
  • Seek support…
  • Stay positive…”.7

Benefits

What benefits may accompany an empty nest?

In 4 Tips for Enjoying Your Empty Nest: Benefits To Empty Nesters the Mayo Clinic explain:

“As hard as the change may be, having an empty nest can bring benefits to parents. Recent studies suggest that an empty nest might reduce work and family conflicts. Having an empty nest also gives parents a new opportunity to reconnect with each other, improve the quality of their marriage and rekindle interests with newfound time”.8

Health Care Provider

What if I think I have empty nest syndrome?

In How To Cope With Empty Nest Syndrome: When To Get Help the Cleveland Clinic elaborate on:

“Everybody’s empty nest journey looks a little bit different. And that’s OK. But it raises a question: How do you know when run-of-the-mill empty nest syndrome has graduated into something more serious? Dr. Borland recommends reaching out to your primary care physician or a mental health professional if you:

  • Don’t feel your symptoms are improving with time — or worry they’re getting worse
  • Experience anxiety, depression, stress or panic to a degree that interferes with your daily life
  • Experience mood swings, like crying without warning or becoming excessively angry
  • Isolate yourself from others or stop doing activities you enjoy
  • Have difficulty concentrating
  • Hear from concerned loved ones that they’ve noticed a change in your behavior
  • Feel you can’t experience happiness like you used to

It’s also important to keep tabs on your physical well-being. The following are good indicators you need additional support…

If you don’t already have a therapist, talk to your primary care provider about getting a referral. Also, consider availing yourself of resources like empty nest support groups and self-help books”.9

Health Topics A-Z

Where may I find Health Topics A-Z related to Empty Nest Syndrome?

In Health Topics A-Z you may find:

Health Topics A-Z

  • Anxiety
  • Complementary and Integrative Health and Menopause
  • Depression
  • Menopause
  • Menopause Blues
  • Menopause Psychological Symptoms
  • Menopause Reaction
  • Menopause Self Esteem
  • Mental Health
  • Stress Management

Links

Where may I find Links related to Empty Nest Syndrome?

Your Country may have Links similar to:

Links

This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.

New or Updated
  • How To Cope With Empty Nest Syndrome [16 August 2024]
  • Mental Health Awareness Week [11-17 May 2026, United Kingdom]
    Menopause News May 2026
  • Mental Health Month [May, United States]
    Menopause News May 2026
  • Online Events [International Menopause Society]: Past Webinars – 2025: Lifestyle Medicine 14 October 2025]
  • When Hormones Are Missed In Mental Health [24 March 2026]
  • World Menopause Day 2025 [18 October]

  1. 4 Tips for Enjoying Your Empty Nest
  2. ACOG Explains: Managing Menopause Symptoms [American College of Obstetricians and Gynecologists]
  3. Anxiety Disorders
  4. Anxiety Self-Help Guide
  5. Anxiety vs. Depression: Which Do I Have (or Is It Both)?
  6. BMS TV: Menopause Explained
  7. BMS TV: Menopause – Weight Gain, Nutrition and Lifestyle
  8. Boost Your Mood With Mind-Nourishing Food
  9. CBT for Menopausal Symptoms
  10. Can Menopause Cause Depression?
  11. Consumer Video and Podcast Series: 2024 Consumer Videos and Podcasts – Cognitive Behavioral Therapy and Menopause
  12. Consumer Video and Podcast Series: 2024 Consumer Videos and Podcasts – Preparing for Your Menopause Health Care Visit
  13. Depression [+ Video Courtesy: Mayo Clinic News Network]
  14. Depression In Women: 4 Things To Know
    Empty Nest Syndrome
  15. Does Menopause Really Cause Depression?
  16. EMAS On-Demand Webinars [European Menopause and Andropause Society] [Multiply Languages]: Menopause and Mental Health: Managing Anxiety, Depression, and Cognitive Changes
  17. Emotional Well-Being
  18. Emotional Wellness In Menopause
  19. Empowering the Health of Women In Midlife
    Empty Nest Syndrome
  20. Empty Nest Syndrome
  21. Empty Nest Syndrome
  22. Empty Nesters
  23. Empty Nesters
    Empty Nest Syndrome
  24. Everything You Need To Know About Menopausal Brain Fog but Are Afraid To Ask — and No, ‘You’re Not Losing Your Mind’
  25. Experts Answer Your Menopause Questions In Video
  26. Feeling Lonely
  27. Feeling Stuck? Brainspotting May Help
  28. Getting Help for Mental Health
  29. How Do I Know If I Have A Mental Health Problem? [Video]
  30. How Mindfulness Meditation Improves Mental Health
  31. How Small Lifestyle Changes Can Transform Your Health
  32. How To Cope With Empty Nest Syndrome
  33. How To Manage Fear and Anxiety
  34. How To Manage Menopausal Insomnia
  35. How To Manage and Reduce Stress
  36. How To Talk To Your Doctor About Menopause
  37. How To Talk To Your Doctor About Midlife Brain Fog
  38. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Menopause and Your Mental Wellbeing [+ Video: Menopause Only Affects You Physically!] [Other Languages and Formats]
  39. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Signs and Symptoms of Menopause [+ Video: Talking Menopause With Your GP] [Other Languages and Formats]
  40. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Supporting Someone Through the Menopause [+ Video: Men Don’t Need To Know About Menopause] [Other Languages and Formats]
  41. Mastering Midlife Mood Changes With Marlene Freeman, MD
  42. Mayo Clinic Minute: Perimenopause and Menopause [+ Video]
  43. Mayo Clinic Q and A: Countdown To Control Anxiety
  44. Mayo Clinic Q and A: Mindfulness and Mental Health
  45. Mayo Clinic Q and A: Perimenopause Transitions and Concerns
  46. Menopause
  47. Menopause
  48. Menopause
    Empty Nest Syndrome
  49. Menopause Depression
  50. Menopause Depression: Under Recognised and Poorly Treated
  51. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  52. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Symptom Tracker
    Empty Nest Syndrome
  53. Menopause and Mental Health
  54. Menopause: Ensuring A Tranquil Transition
  55. Menopause: Things You Can Do
  56. Menopause and Depression: Is There A Link?
  57. Menopause and Mental Health
  58. Mental Health and Menopause: There Are connections and Solutions
  59. Moderate Exercise Linked To Lower Depression Risk
  60. Mood and the Menopause
  61. Moving From An Empty Nest To Post-Parental Growth
  62. Mymenoplan.org [My Menoplan, United States]
  63. Lifestyle Medicine National Center for Complementary and Integrative Health: Depression
  64. National Center for Complementary and Integrative Health: How Safe Is This Product or Practice?
  65. National Self-Care Week [17 – 23 November 2025, United Kingdom]
  66. Navigating Menopause Care Resource Guide
  67. Online Events [International Menopause Society]: Past Webinars – 2025: Lifestyle Medicine
  68. Our Best Mental Health Tips – Backed By Research
  69. Perimenopause
  70. Perimenopause
  71. Perimenopause and Menopause Checklist: Translated Checklists
  72. Perimenopause and Menopause Symptom Checklist
  73. Perimenopause and Menopause Toolkit
  74. Postmenopause
  75. Power Up: 10 Ways To Boost Your Energy Naturally
  76. Promoting Good Mental Health Over the Menopause Transition
  77. Resilience Training
  78. Resilience: Build Skills To Endure Hardship
  79. Self-Esteem: Take Steps To Feel Better About Yourself
  80. Self-Help Tool: Menopause and Mental Wellbeing
  81. Should You Try an L-Tyrosine Supplement? A Look at Its Benefits and Side Effects
  82. Sleep
  83. Sleep, Food, Exercise, Stress: Why Working on One of These Can Improve the Others
  84. Surprising Menopause Symptoms Revisited | Dr Louise Newson
  85. Talking To Your GP About Your Mental Health
  86. The Exercise Effect
  87. Therapy Could Be Effective Treatment for Non-Physical Symptoms of Menopause
  88. Tips To Help Manage Menopause Symptoms
  89. Top Tips To Improve Your Mental Wellbeing
  90. Videos & Podcasts: Videos – Menopause and Hormone Therapy: Current Perspectives and Controversies
  91. Videos and Podcasts: Videos – A Simple Approach To Menopause: The Menopause Quick Six (www.MQ6.ca)
  92. What Are the Most Common Symptoms of Menopause? And Which Can Hormone Therapy Treat?
  93. What Everyone Should Know About Menopause Symptoms
  94. What Is Cognitive Behavioral Therapy?
  95. What’s the Link Between the Menopause and Anxiety?
  96. When Hormones Are Missed In Mental Health
  97. World Menopause Day 2025 [18 October]
    Empty Nest Syndrome
  98. Your Daily Dose: Let’s Unpack Menopause
  99. Your Daily Dose: Perimenopause, Don’t Suffer In Silence

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. 4 Tips for Enjoying Your Empty Nest. 19 September 2022. Mayo Clinic https://newsnetwork.mayoclinic.org/discussion/4-tips-for-enjoying-your-empty-nest/ Accessed: 06 April 2026
  2. 4 Tips for Enjoying Your Empty Nest. 19 September 2022. Mayo Clinic https://newsnetwork.mayoclinic.org/discussion/4-tips-for-enjoying-your-empty-nest/ Accessed: 06 April 2026
  3. How To Cope With Empty Nest Syndrome: What Is Empty Nest Syndrome? 16 August 2024. Cleveland Clinic https://health.clevelandclinic.org/empty-nest-syndrome Accessed: 06 April 2026
  4. Empty Nest Syndrome: What Age Group Is Empty Nest Syndrome Associated? Last Reviewed: 29 October 2021. PsychCentral https://psychcentral.com/health/empty-nest-syndrome#remedies-for-empty-nest-syndrome Accessed: 06 April 2026
  5. How To Cope With Empty Nest Syndrome: Symptoms. 16 August 2024.  Cleveland Clinic https://health.clevelandclinic.org/empty-nest-syndrome Accessed: 06 April 2026
  6. Menopause and Mental Health: Mental Health Symptoms Related To Menopause. 05 September 2025. Australasian Menopause Society https://www.menopause.org.au/health-info/fact-sheets/menopause-and-mental-health Accessed: 06 April 2026
  7. 4 Tips for Enjoying Your Empty Nest: Advice for the Transition. 19 September 2022. Mayo Clinic https://newsnetwork.mayoclinic.org/discussion/4-tips-for-enjoying-your-empty-nest/ Accessed: 06 April 2026
  8. 4 Tips for Enjoying Your Empty Nest: Benefits To Empty Nesters. 19 September 2022. Mayo Clinic https://newsnetwork.mayoclinic.org/discussion/4-tips-for-enjoying-your-empty-nest/ Accessed: 06 April 2026
  9. How To Cope With Empty Nest Syndrome: When To Get Help. 16 August 2024. Cleveland Clinic https://health.clevelandclinic.org/empty-nest-syndrome Accessed: 06 April 2026
Topic Last Updated: 06 April 2026 – Topic Last Reviewed: 06 April 2026

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April 6, 2026/by MWD
Tags: Anxiety, Depression, Empty Nest Syndrome, Healthy Living, Menopause Blues, Mental Health
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