Hormone Therapy and Tibolone

Hormone Therapy and Tibolone

“Tibolone is a type of hormone replacement therapy (HRT)
that contains a synthetic (artificial) hormone. Your body
breaks down tibolone to make substances that work in a…”.1

Umbrella

What may the Hormone Therapy and Tibolone Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Livial
  • Menopausal Hormone Therapy (MHT)
  • Tibolone
  • Xyvion

Date

What can it be important to be clear about with Hormone Therapy (HT) and Tibolone information?

It can be important to be clear about the date of all information including the date of HT information, because this information may have been updated.

Symptoms or Chronic Conditions

What can it also be important to be clear about with HT and Tibolone information?

It can also be important to be clear about whether HT information is about the use of HT for the management of menopausal symptoms such as hot flushes, night sweats and vaginal dryness or for the prevention of chronic conditions such as cardiovascular disease and osteoporosis.

Definition

What is Tibolone?

DotS the definition of Tibolone may vary. In Hormone Replacement Therapy (HRT): Tibolone – About Tibolone: Brand Name: Livial, last reviewed 05 January 2023, the (United Kingdom) NHS’s definition is:

“Tibolone is a type of hormone replacement therapy (HRT) that contains a synthetic (artificial) hormone. Your body breaks down tibolone to make substances that work in a similar way to the hormones oestrogen, progesterone and testosterone”.2

Bleed-Free

Is Tibolone bleed-free?

On page two in HRT: Which HRT? Tibolone the (British) Women’s Health Concern’s (WHC) note:

“The first “bleed-free” HRT contains a synthetic hormone known as Tibolone, which is taken orally every day. Tibolone has combined oestrogen, progestogen and testosterone effects and relieves menopausal symptoms, prevents bone loss, and may improve interest in sex. As with other continuous therapies, it is normally prescribed at least 12 months after the last menstrual period, so many women switch to these continuous types after taking a sequential HRT”.3

Menopause Symptoms

What menopause symptoms does Tibolone help to improve?

In Hormone Replacement Therapy (HRT): Tibolone – About Tibolone: Brand Name: Livial the NHS note:

“Tibolone helps to improve menopause symptoms, such as hot flushes, low mood and vaginal dryness or irritation”.4

In Tibolone As Menopausal Hormone Therapy: Summary, updated 25 September 2023, the Australasian Menopause Society (AMS) explain:

“Tibolone is indicated for the management of vasomotor symptoms associated with the menopause and for the prevention of bone loss. It can be considered an alternative to conventional MHT where improvement in libido is desired”.5

In The 2023 Practitioner’s Toolkit for Managing Menopause: The 2023 Practitioner’s Toolkit for Managing the Menopause Supporting Notes – Management: MHT Formulations and Options: Tibolone, published online 30 October 2023, the authors also note:

“It may improve sexual interest and responsiveness. Breast tenderness is uncommon and tibolone does not increase mammographic density”.6

Osteoporosis

How useful is Tibolone in women who have osteoporosis?

The NHS note:

“It can also be prescribed to help stop your bones getting thinner after the menopause (osteoporosis)”.7

Endometriosis and Fibroids

How useful is Tibolone in women who are known to have endometriosis and fibroids?

On page two in HRT: Which HRT? Tibolone the WHC explain:

“Tibolone has also been shown to be particularly useful in women who are known to have endometriosis and fibroids as it does not appear to stimulate these conditions”.8

Health Care Provider

What if I choose to use Tibolone?

If you choose to use Tibolone it may be in your best interest to also choose to talk to your health care provider about this.

In Tibolone As Menopausal Hormone Therapy: Summary the AMS note:

“It is not recommended for use in women with a history of breast cancer and should be used with caution in women over age 60 because of the increased stroke risk”.9

On page two in HRT: Which HRT? Tibolone the WHC elaborate on:

“Irregular bleeding or spotting can occur during the first 4-6 months of taking continuous combined HRT or Tibolone, and is not a cause for alarm. However, you should consult your doctor if you get heavy (rather than light) bleeding, if it lasts for more than six months, or if bleeding starts suddenly after some time without bleeding. Irregular bleeding may sometimes be improved by changing the type or route of HRT”.10

In Hormone Replacement Therapy (HRT): Tibolone – About Tibolone: Brand Name: Livial – Key Facts the NHS elaborate on:

  • “It’s important to see your doctor at least once a year for a check-up and to review whether you need to keep taking tibolone”.11

Health Topics A-Z

Where may I find Health Topics A-Z related to Hormone Therapy and Tibolone?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy and Tibolone?

Your Country may have Links similar to:

Links

This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.

New or Updated

  1. ACOG Explains: Managing Menopause Symptoms [American College of Obstetricians and Gynecologists]
  2. Active Ingredient: Tibolone [Tibolone (Sandoz), Xyvion and Livial]
  3. Askearlymenopause.org [Ask EM] [+ Video: What Is Early Menopause?]
  4. BMS TV: Hormone Replacement Therapy (HRT)
  5. Bioidentical Hormones: Are They Safer?
  6. Boosting Bone Density: Best Ways To Prevent Fractures As You Age
  7. Brand Name Tibolone (Sandoz)
  8. Build Better Bones.org [International Osteoporosis Foundation]
  9. Consumer Video and Podcast Series: 2024 Consumer Videos and Podcasts – Preparing for Your Menopause Health Care Visit
  10. Custom-Mixed Hormone Therapies Misleading Menopausal Women To Think Personalised Products Are Necessary, Experts Say
  11. Deciding About Hormone Therapy
  12. Deciding About Hormone Therapy Use
  13. Emotional Wellness In Menopause
  14. FAQs: Hormone Therapy for Menopause
  15. FDA Direct: Removing Black Box Warnings for HRT (Part 1/2)
  16. FDA Direct: Removing Black Box Warnings for HRT (Part 2/2)
  17. Find A Menopause Practitioner [United States and Other]
  18. Find A Practitioner [Australasian Menopause Society i.e. Australia and New Zealand]
  19. Find Your Nearest BMS Menopause Specialist [British Menopause Society]
  20. Genitourinary Syndrome of Menopause
  21. HRT
  22. HRT Questions Answered
  23. HRT – Types, Doses and Regimens
  24. HRT: Benefits and Risks
  25. Handling Hot Flushes and Night Sweats| Dr Louise Newson
  26. Hormone Replacement Therapy (HRT)
  27. Hormone Replacement Therapy (HRT): Benefits and Risks of Hormone Replacement Therapy (HRT)
  28. Hormone Replacement Therapy (HRT): Side Effects of Hormone Replacement Therapy (HRT)
  29. Hormone Replacement Therapy (HRT): Tibolone – About Tibolone: Brand Name: Livial
  30. Hormone Replacement Therapy (HRT): Tibolone – Brand Name: Livial
  31. Hormone Replacement Therapy (HRT): Tibolone Brand Name: Livial – Common Questions About Tibolone
  32. Hormone Replacement Therapy (HRT): Tibolone Brand Name: Livial – How and When To Take Tibolone
  33. Hormone Replacement Therapy (HRT): Tibolone Brand Name: Livial – Side Effects
  34. Hormone Replacement Therapy (HRT): Tibolone Brand Name: Livial – Taking Tibolone With Other Medicines and Herbal Supplements
  35. Hormone Replacement Therapy (HRT): Tibolone Brand Name: Livial – Who Can and Cannot Take Tibolone
  36. Hormone Replacement Therapy (HRT): Types of Hormone Replacement Therapy (HRT)
  37. Hormone Replacement Therapy (HRT): Vaginal Oestrogen
  38. Hormone Therapy: Is It Right for You?
  39. Hot Flashes
  40. Hot Flashes
  41. How To Find Relief for Hot Flashes At Night
  42. How Vaginal Hormones Can Transform the Health of Women
  43. International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause
  44. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  45. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – After the Menopause [Other Languages and Formats]
  46. Livial Tablets
  47. Managing Menopause Symptoms [+ Video Courtesy: Mayo Clinic News Network]
  48. May Is Osteoporosis Awareness and Prevention Month!
    Hormone Therapy and Tibolone
  49. Menopause
  50. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  51. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
  52. Menopause Treatment
  53. Menopause and HRT: Fact and Fiction
  54. Menopause and Mental Health
  55. Menopause, Perimenopause, Hormone Therapy and Other Treatments With Madelyn Butler, MD [Podcast]
  56. Menopause: Identification and Management [NICE Guideline]
  57. Menopause: Identification and Management [NICE Guideline]Hormone Therapy and Tibolone
  58. Mood and the Menopause
  59. National Center for Complementary and Integrative Health: Herbs At A Glance
  60. National Center for Complementary and Integrative Health: How Safe Is This Product or Practice?
  61. Navigating Menopause Care Resource Guide
  62. Online Events [International Menopause Society]: IMS Partnership Symposia Series – What’s Hot? Options for Treatment of Hot Flushes 2025
  63. Online Events [International Menopause Society]: Past Webinars – 2024: Approach To Bone Health In the Perimenopause and Postmenopause?
  64. Online Events [International Menopause Society]: Past Webinars – 2025: Changing the Paradigm for Earlier Osteoporosis Prevention
  65. Online Events [International Menopause Society]: Past Webinars – 2026: New IMS Recommendations: Evidence-Based Management of Vasomotor Symptoms
  66. Online Events [International Menopause Society]: Past Webinars – 2026: New IMS Recommendations – Midlife Body Changes
  67. Osteoporosis
  68. Professional Video and Podcast Series: 2025 Professional Videos and Podcasts – Hypoactive Sexual Desire Disorder HSDD—Open the Door To Discussion
  69. Secret To Strong Bones After 50 (Not All Calcium!)
  70. Sex and Sexual Health
  71. Sex and Sexual Health As You Age
  72. Talk About Painful Sex
  73. Testosterone Therapy In Women: Does It Boost Sex Drive?
  74. The 2023 Practitioner’s Toolkit for Managing Menopause
  75. The Menopause Society Show: Menopause & Sexual Desire
  76. Tibolone Tablets
  77. Urogenital Problems
  78. Videos & Podcasts: Videos – Menopause and Hormone Therapy: Current Perspectives and Controversies [18 October 2024]
  79. Videos & Podcasts: Videos – Preventing Bone Loss At Menopause
  80. What Is the Difference Between Perimenopause, Menopause and Postmenopause?
  81. What Types of Vaginal Oestrogens Are There?
  82. World Menopause Day 2024: Leaflet for Women – Menopause and Menopause Hormone Therapy [Multiply Languages]
  83. Your Daily Dose: Let’s Unpack Menopause

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Hormone Replacement Therapy (HRT): Tibolone – About Tibolone: Brand Name: Livial. Page Last Reviewed: 05 January 2023. NHS https://www.nhs.uk/medicines/hormone-replacement-therapy-hrt/tibolone/about-tibolone/ Accessed: 19 June 2026
  2. Hormone Replacement Therapy (HRT): Tibolone – About Tibolone: Brand Name: Livial. Page Last Reviewed: 05 January 2023. NHS https://www.nhs.uk/medicines/hormone-replacement-therapy-hrt/tibolone/about-tibolone/ Accessed: 19 June 2026
  3. HRT: Which HRT? Tibolone. Reviewed: November 2021:2. Women’s Health Concern https://www.womens-health-concern.org/wp-content/uploads/2022/12/09-WHC-FACTSHEET-HRT-NOV2022-B.pdf Accessed: 19 June 2026
  4. Hormone Replacement Therapy (HRT): Tibolone – About Tibolone: Brand Name: Livial. Page Last Reviewed: 05 January 2023. NHS https://www.nhs.uk/medicines/hormone-replacement-therapy-hrt/tibolone/about-tibolone/ Accessed: 19 June 2026
  5. Tibolone As Menopausal Hormone Therapy: Summary. 25 September 2023. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/tibolone-as-menopausal-hormone-therapy Accessed: 19 June 2026
  6. Davis, S. R., Taylor, S., Hemachandra, C., Magraith, K., Ebeling, P. R., Jane, F., and Islam, R. M. The 2023 Practitioner’s Toolkit for Managing Menopause: The 2023 Practitioner’s Toolkit for Managing the Menopause Supporting Notes – Management: MHT Formulations and Options: Tibolone. Published Online: 30 October 2023 https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783 Accessed: 19 June 2026
  7. Hormone Replacement Therapy (HRT): Tibolone – About Tibolone: Brand Name: Livial. Page Last Reviewed: 05 January 2023. NHS https://www.nhs.uk/medicines/hormone-replacement-therapy-hrt/tibolone/about-tibolone/ Accessed: 19 June 2026
  8. HRT: Which HRT? Tibolone. Reviewed: 2021:2. Women’s Health Concern https://www.womens-health-concern.org/wp-content/uploads/2022/12/09-WHC-FACTSHEET-HRT-NOV2022-B.pdf Accessed: 19 June 2026
  9. Tibolone As Menopausal Hormone Therapy: Summary. 25 September 2023. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/tibolone-as-menopausal-hormone-therapy Accessed: 19 June 2026
  10. HRT: Which HRT? Tibolone. Reviewed: 2021:2. Women’s Health Concern https://www.womens-health-concern.org/wp-content/uploads/2022/12/09-WHC-FACTSHEET-HRT-NOV2022-B.pdf Accessed: 19 June 2026
  11. Hormone Replacement Therapy (HRT): Tibolone – About Tibolone: Brand Name: Livial – Key Facts. Page Last Reviewed: 05 January 2023. NHS https://www.nhs.uk/medicines/hormone-replacement-therapy-hrt/tibolone/about-tibolone/ Accessed: 19 June 2026
Topic Last Updated: 19 June 2026 – Topic Last Reviewed: 19 June 2026

Print Friendly, PDF & Email
/by
Copyright © 2011 – 2026 Meno Martha®. All Rights Reserved. | The information provided on  Meno Martha, Meno Martha International Menopause Directory and/or menomartha.com is for informational or educational purposes only. It is not intended to substitute for or replace the medical advice, diagnosis or treatment of your qualified health care providers. | By using this service you accept Meno Martha International Menopause Directory’s Terms of Use which incorporate Meno Martha International Menopause Directory’s Links Policy. | Meno Martha® is a registered Trademark | Meno Martha International Menopause Directory® is a registered Trademark.
Meno Martha and/or Meno Martha International Menopause Directory do not sell, produce or endorse any products, services or content of any kind including pills or potions for ‘menopause symptom relief’. Please Contact Us if you see or receive any advertisements allegedly by, for or on behalf of Meno Martha and/or Meno Martha International Menopause Directory.