Hormone Therapy and Tibolone

“Tibolone (brand name Livial) is a prescription medicine
that is similar to taking combined HRT (oestrogen and
progestogen). It’s taken as a tablet once a day”.1

Umbrella
What may the Hormone Therapy and Tibolone Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Livial
  • Menopausal Hormone Therapy (MHT)
  • Tibolone
  • Xyvion

Definition

What is Tibolone?

DotS the definition of Tibolone may vary. The Australasian Menopause Society’s (AMS) definition is:

  • “Tibolone acts as a combined oral hormone therapy for treating menopausal symptoms”.2

The (United Kingdom) NHS’s definition is:

“Tibolone (brand name Livial) is a prescription medicine that is similar to taking combined HRT (oestrogen and progestogen). It’s taken as a tablet once a day”.3

In Menopausal Hormone Therapy the European Menopause and Andropause Society’s definition is:

  • “Tibolone is a synthetic steroid with estrogenic, progestogenic and weak androgenic activity used to manage menopausal symptoms and urogenital atrophy in postmenopausal women”.4

On page two in HRT: Which HRT? Tibolone the (British) Women’s Health Concern’s note:

“The first “bleed-free” HRT contains a synthetic hormone known as Tibolone, which is taken orally every day. Tibolone has combined oestrogen, progestogen and testosterone effects and relieves menopausal symptoms, prevents bone loss, and may improve interest in sex. As with other continuous therapies, it is normally prescribed at least 12 months after the last menstrual period, so many women switch to these continuous types after taking a sequential HRT. Tibolone has also been shown to be particularly useful in women who are known to have endometriosis and fibroids as it does not appear to stimulate these conditions”.5

Menopause Symptoms

How effective is Tibolone for menopause symptoms?

In Tibolone As Menopausal Hormone Therapy: How Effective Is Tibolone? the AMS elaborate on:

“In randomized trials tibolone 2.5mg has been found to be more effective than placebo and less effective than standard dose combined MHT in controlling vasomotor symptoms”.6

In Hormone Replacement Therapy (HRT) Alternatives – Tibolone the NHS note:

Hormone Therapy and Tibolone“It can help relieve symptoms such as hot flushes, low mood and reduced sex drive, although some studies have suggested it may not be as effective as combined HRT”.7

Bone Loss

How effective is Tibolone in the prevention of bone loss?

In Tibolone As Menopausal Hormone Therapy: How Effective Is Tibolone? the AMS elaborate on:

  • “Tibolone has been found to be effective in the prevention of bone loss”.8

Health Care Provider

What if I choose to use Tibolone?

If you choose to use Tibolone it may be in your best interest to also choose to talk to your health care provider about this.

In Hormone Replacement Therapy (HRT) Alternatives – Tibolone the NHS note:

“Risks of tibolone are similar to the risks of HRT, and include an increased risk of breast cancer and strokes. Talk to your GP about the risks and benefits of tibolone if you’re considering taking it”.9

Health Topics A-Z

Where may I find Health Topics related to Hormone Therapy and Tibolone?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy and Tibolone?

Your Country may have Links similar to:

Links

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New or Updated

  1. Active Ingredient: Tibolone [Tibolone (Sandoz), Xyvion and Livial]
  2. Askearlymenopause.org [Ask EM] [+ Video: What Is Early Menopause?]
  3. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  4. BMS Statement on Testosterone
  5. BMS TV: Testosterone Explained
  6. Bioidentical Hormones Explained – A British Menopause Society Video
  7. Bioidentical Hormones: Are They Safer?
  8. Brand Name Tibolone (Sandoz)
  9. Combined Menopausal Hormone Therapy (MHT)
  10. Complementary and Alternative Therapies Explained – A British Menopause Society Video
  11. Consumer Health: Menopause, Hormone Replacement Therapy and Heart Health
  12. Deciding About Hormone Therapy Use
  13. Dr Gail Busby – I Forgot To Ask the Doctor – Episode 9 The Menopause
  14. Find A Menopause Practitioner [United States and Other]
  15. Find An AMS Doctor [Australasian Menopause Society i.e. Australia and New Zealand]
  16. Find Your Nearest BMS Menopause Specialist [British Menopause Society]
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  19. HRT and Alternatives
  20. HRT and Breast Cancer: Overall Risks and Benefits Explained – A British Menopause Society Video
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  25. Hormone Replacement Therapy (HRT)
  26. Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
  27. Hormone Replacement Therapy (HRT) With Dr Nicky Peel & Prof. David Armstrong
  28. Hormone Replacement Therapy (HRT): Alternatives – Tibolone
  29. Hormone Replacement Therapy (HRT): Risks
  30. Hormone Replacement Therapy (HRT): Types
  31. Hormone Therapy for Menopause
  32. Hormone Therapy: Is It Right for You?
  33. Hot Flashes
  34. Hot Flashes
  35. Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
  36. How To Find Relief for Hot Flashes At Night
  37. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  38. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – After the Menopause
  39. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?]
  40. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Signs and Symptoms [+ Video: Talking Menopause With Your GP]
  41. Livial Tablets
  42. Managing Your Symptoms
  43. Mastering Midlife Mood Changes With Marlene Freeman, MD
  44. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video Courtesy: Mayo Clinic News Network]
  45. Menopausal Hormone Therapy
  46. Menopause
  47. Menopause
  48. Menopause
  49. Menopause FAQs: Hormone Therapy for Menopause Symptoms
  50. Menopause Management Options
  51. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
    Hormone Therapy and Tibolone
  52. Menopause Map: Downloadable Resources – Stages of Menopause: Postmenopause
    Postmenopause
  53. Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
  54. Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
  55. Menopause Patient Information [Videos] 4. The Different Types of HRT
  56. Menopause Preparedness Toolkit Video Series: Common Conditions Associated With Menopause and Midlife
  57. Menopause Preparedness Toolkit Video Series: Treating Vasomotor Symptoms of Menopause
  58. Menopause Preparedness Toolkit: A Woman’s Empowerment Guide
  59. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
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  61. Menopause Treatments: What Works, What Doesn’t
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  69. National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
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  71. Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
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  73. Oestrogen Only Menopausal Hormone Therapy
  74. Osteoporosis Explained – A British Menopause Society Video
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  76. Short-Term and Long-Term Effects of Tibolone In Postmenopausal Women
  77. Supporting Women Through Menopause – Fact Sheet
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  79. Testosterone Therapy In Women: Does It Boost Sex Drive?
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  89. Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
  90. Video Series-2022: Perimenopause, Signs, Symptoms, and Solutions
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Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Hormone Replacement Therapy (HRT): Alternatives – Tibolone. Page Last Reviewed: 09 September 2019. NHS https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/alternatives/#tibolone Accessed: 14 March 2023
  2. Tibolone As Menopausal Hormone Therapy: Key Points. Content Updated December 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/793-tibolone-for-post-menopausal-women Accessed: 14 March 2023
  3. Hormone Replacement Therapy (HRT): Alternatives – Tibolone. Page Last Reviewed: 09 September 2019. NHS https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/alternatives/#tibolone Accessed: 14 March 2023
  4. Menopausal Hormone Therapy. 2022. European Menopause and Andropause Society https://emas-online.org/wp-content/uploads/2022/05/Menopausal-hormone-therapy.pdf Accessed: 14 March 2023
  5. HRT: Which HRT? Tibolone. Reviewed November 2021. Publication Date 2021:2. Women’s Health Concern https://www.womens-health-concern.org/wp-content/uploads/2022/12/09-WHC-FACTSHEET-HRT-NOV2022-B.pdf Accessed: 14 March 2023
  6. Tibolone As Menopausal Hormone Therapy: How Effective is Tibolone? Content Updated December 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/793-tibolone-for-post-menopausal-women Accessed: 14 March 2023
  7. Hormone Replacement Therapy (HRT): Alternatives – Tibolone. Page Last Reviewed: 09 September 2019. NHS https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/alternatives/#tibolone Accessed: 14 March 2023
  8. Tibolone As Menopausal Hormone Therapy: How Effective is Tibolone? Content Updated December 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/793-tibolone-for-post-menopausal-women Accessed: 14 March 2023
  9. Hormone Replacement Therapy (HRT): Alternatives – Tibolone. Page Last Reviewed: 09 September 2019. NHS https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/alternatives/#tibolone Accessed: 14 March 2023
Topic Last Updated: 14 March 2023 – Topic Last Reviewed: 14 March 2023

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