“Tibolone (brand name Livial) is a prescription medicine
that is similar to taking combined HRT (oestrogen and
progestogen). It’s taken as a tablet once a day”.1

Umbrella
What may the Hormone Therapy and Tibolone Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Livial
  • Menopausal Hormone Therapy (MHT)
  • Tibolone
  • Xyvion

Definition

What is Tibolone?

DotS the definition of Tibolone may vary. The Australasian Menopause Society’s (AMS) definition is:

  • “Tibolone acts as a combined oral hormone therapy for treating menopausal symptoms”.2

The (United Kingdom) NHS’s definition is:

“Tibolone (brand name Livial) is a prescription medicine that is similar to taking combined HRT (oestrogen and progestogen). It’s taken as a tablet once a day”.3

Continuous

Is Tibolone continuous?

In HRT: Which HRT? Tibolone the (British) Women’s Health Concern (WHC) explain:

“As with other continuous therapies, is normally prescribed at least 12 months after the last menstrual period, so many women switch to these continuous types after taking a sequential HRT”.4

Vasomotor Symptoms

How effective is Tibolone for vasomotor symptoms such as hot flushes and night sweats?

In Tibolone As Menopausal Hormone Therapy: How Effective Is Tibolone? the AMS elaborate on:

“In randomized trials tibolone 2.5mg has been found to be more effective than placebo and less effective than standard dose combined MHT in controlling vasomotor symptoms”.5

Menopause Symptoms

How effective is Tibolone for menopause symptoms?

In Hormone Replacement Therapy (HRT) Alternatives – Tibolone the NHS note:

Hormone Therapy and Tibolone“It can help relieve symptoms such as hot flushes, low mood and reduced sex drive, although some studies have suggested it may not be as effective as combined HRT”.6

In HRT: Which HRT? Tibolone the (British) Women’s Health Concern (WHC) explain:

“Tibolone has combined oestrogen, progestogen and testosterone effects and relieves menopausal symptoms, prevents bone loss, and may improve interest in sex”.7

Bone Loss

How effective is Tibolone in the prevention of bone loss?

In Tibolone As Menopausal Hormone Therapy: How Effective Is Tibolone? the AMS elaborate on:

  • “Tibolone has been found to be effective in the prevention of bone loss”.8

Endometriosis and Fibroids

Is Tibolone useful in women known to have endometriosis and fibroids?

The WHC note:

“Tibolone has also been shown to be particularly useful in women who are known to have endometriosis and fibroids as it does not appear to stimulate these conditions”.9

Health Care Provider

What if I choose to use Tibolone?

If you choose to use Tibolone it may be in your best interest to also choose to talk to your health care provider about this.

In Hormone Replacement Therapy (HRT) Alternatives – Tibolone the NHS note:

“Risks of tibolone are similar to the risks of HRT, and include an increased risk of breast cancer and strokes. Talk to your GP about the risks and benefits of tibolone if you’re considering taking it”.10

Health Topics A-Z

Where may I find Health Topics related to Hormone Therapy and Tibolone?

In Health Topics A-Z you may find:

Links

Where may I find Links related to Hormone Therapy and Tibolone?

Your Country may have Links similar to:

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Hormone Replacement Therapy (HRT): Alternatives – Tibolone. Page Last Reviewed: 09 September 2019. NHS https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/alternatives/#tibolone Accessed: 01 October 2022
  2. Tibolone As Menopausal Hormone Therapy: Key Points. Content Updated December 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/793-tibolone-for-post-menopausal-women Accessed: 01 October 2022
  3. Hormone Replacement Therapy (HRT): Alternatives – Tibolone. Page Last Reviewed: 09 September 2019. NHS https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/alternatives/#tibolone Accessed: 01 October 2022
  4. HRT: Which HRT? Tibolone. Reviewed: November 2021. British Women’s Health Concern https://www.womens-health-concern.org/help-and-advice/factsheets/hrt/ Accessed: 01 October 2022
  5. Tibolone As Menopausal Hormone Therapy: How Effective is Tibolone? Content Updated December 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/793-tibolone-for-post-menopausal-women Accessed: 01 October 2022
  6. Hormone Replacement Therapy (HRT): Alternatives – Tibolone. Page Last Reviewed: 09 September 2019. NHS https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/alternatives/#tibolone Accessed: 01 October 2022
  7. HRT: Which HRT? Tibolone. Reviewed: November 2021. British Women’s Health Concern https://www.womens-health-concern.org/help-and-advice/factsheets/hrt/ Accessed: 01 October 2022
  8. Tibolone As Menopausal Hormone Therapy: How Effective is Tibolone? Content Updated December 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/793-tibolone-for-post-menopausal-women Accessed: 01 October 2022
  9. HRT: Which HRT? Tibolone. Reviewed: November 2021. British Women’s Health Concern https://www.womens-health-concern.org/help-and-advice/factsheets/hrt/ Accessed: 01 October 2022
  10. Hormone Replacement Therapy (HRT): Alternatives – Tibolone. Page Last Reviewed: 09 September 2019. NHS https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/alternatives/#tibolone Accessed: 01 October 2022
Topic Last Updated: 01 October 2022 – Topic Last Reviewed: 01 October 2022

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