Hormone Therapy Postmenopause

“Hormone therapy postmenopause “benefits are more likely to outweigh risks if initiated for symptomatic women before the age of 60 years or within 10 years after menopause”.1

Umbrella
What may the Hormone Therapy Postmenopause Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT) After Menopause
  • Hormone Therapy (HT) After Menopause
  • Menopausal Hormone Therapy (MHT) After Menopause
  • Postmenopausal/Postmenopause Hormone Replacement Therapy (HRT)/Hormone Therapy (HT)

Revised Global Consensus Statement

What is one of the points of consensus about menopausal hormone therapy (MHT) and postmenopause?

One of the points of consensus in the Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT – endorsed by seven menopause-related organizations – published online 20 June 2016, is:

Hormone Therapy Benefits and Risks

  • “MHT, including tibolone and the combination of conjugated equine estrogens and bazedoxifene (CE/BZA), is the most effective treatment for vasomotor symptoms (VMS) associated with menopause at any age, but benefits are more likely to outweigh risks if initiated for symptomatic women before the age of 60 years or within 10 years after menopause”.2

What are vasomotor symptoms?

DotS the definition of vasomotor symptoms may vary. The North American Menopause Society’s definition is:

“Vasomotor symptoms. Also known as hot flashes and night sweats, common symptoms during perimenopause and early postmenopause”.3

Type and Timing of Menopausal Hormone Therapy and… Meta-Analysis

Hormone Therapy and Breast CancerHormone Therapy and Breast CancerWhat has feedback included about Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Evidence, published in the Lancet on 29 August 2019?

On page one in The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience” the IMS elaborate on:

“Is there new information that menopausal hormone therapy (MHT) substantially increases breast cancer risk as suggested by a paper published in the Lancet this month and should women be worried?

  • Much of the information regarding breast cancer risk and MHT reported in this paper is not new…
  • It is important to note that, because of when the data included in this report was collected, most of the MHT regimes were different from those used today
  • This paper provides an important public health message about obesity and breast cancer risk…”.4

What do the IMS recommend?

On page two in The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience” the IMS explain:

“Recommendations From the IMS

Women enter menopause across a range of ages, with diverse symptoms and health risk profiles. The International Menopause Society advocates the comprehensive assessment of women, including attention to modifying risk factors for chronic disease such as being overweight or obese, the importance of which have been highlighted in this Lancet paper. The benefits and risks of MHT differ according to the timing of menopause such that individualisation of therapy is essential. As prescribing practices have changed significantly over the last decade, further research is needed to determine the impact of currently recommended regimens”.5

In Menopause Experts Dismiss Some Breast Cancer Claims In New Report the (Australian) Jean Hailes for Women’s Health elaborate on:

“Australian menopause experts are urging women to talk to their doctor about their use of menopausal hormone therapy (MHT) if they have concerns following today’s publication of a large study linking MHT to an increased risk of breast cancer”.6

Postmenopausal Bone Health

What are some points of consensus about MHT and postmenopausal bone health?

Some points of consensus in the Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT are:

  • “MHT, including tibolone and CE/BZA, is effective in the prevention of bone loss in postmenopausal women
  • MHT has been shown to significantly lower the risk of hip, vertebral and other osteoporosis-related fractures in postmenopausal women
  • MHT, including tibolone, can be initiated in postmenopausal women at risk of fracture or osteoporosis before the age of 60 years or within 10 years after menopause”.7


What is CE/BZA?

CE/BZA can be an abbreviation for Conjugated Equine Estrogens/Bazedoxifene.

Over Age 60

If I am postmenopausal and over aged 60 years, do I need to stop hormone therapy (HT)?

On page one in the NAMS 2017 Position Statement Updates Guidelines for Hormone Therapy Use the North American Menopause Society note:

  • “For women who initiate HT more than 10 or 20 years from menopause onset or when aged 60 years or older, the benefit-risk ratio appears less favorable than for younger women because of greater absolute risks of coronary heart disease, stroke, venous thromboembolism, and dementia
  • Hormone therapy does not need to be routinely discontinued in women aged older than 60 or 65 years and can be considered for continuation beyond age 65 years for persistent hot flashes, quality-of-life issues, or prevention of osteoporosis after appropriate evaluation and counseling of benefits and risks”.8

Health Care Provider

What if I am postmenopausal and choose to use HT?

If you are postmenopausal and choose to use HT, it may be in your best interest to also choose to talk to your health care provider about this.

One of the points of consensus in the Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT is:

  • “The option of MHT is an individual decision in terms of quality of life and health priorities as well as personal risk factors such as age, time since menopause and the risk of VTE, stroke, ischemic heart disease and breast cancer. MHT should not be recommended without a clear indication for its use”.9

Health Topics A-Z

Where may I find Health Topics related to Hormone Therapy Postmenopause?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy Postmenopause?

Your Country may have Links similar to:

Links

This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.

  1. 9 Myths and Misunderstandings About Menopausal Hormone Therapy (MHT)
  2. Askearlymenopause.org [Ask EM] [+ Video: What Is Early Menopause?]
  3. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  4. Bioidentical Hormone Therapy
  5. Bioidentical Hormones Explained – A British Menopause Society Video
  6. Bioidentical Hormones: Are They Safer?
  7. Cognitive Behaviour Therapy (CBT) for Menopausal Symptoms
  8. Combined Menopausal Hormone Therapy (MHT)
  9. Complementary Medicine Options for Menopausal Symptoms
  10. Complementary and Alternative Therapies Explained – A British Menopause Society Video
  11. Compounded Bioidentical Hormone Therapy [Video]
  12. Consumer Health: Menopause, Hormone Replacement Therapy and Heart Health
  13. Coronary Heart Disease (CHD) Explained – A British Menopause Society Video
  14. EMAS Menopause Essentials
  15. EMAS Replay: Risk Assessment for MHT – When, To Whom, Which, and How Long? [Multiply Languages]
  16. EMAS Replay: The Relevance of Estrogen and Progestogen Choice for Breast Safety During MHT [Multiply Languages]
  17. Early Menopause: Experiences and Perspectives of Women and Health Practitioners
  18. Fast Facts: HRT and Breast Cancer Risk
  19. Find A Menopause Practitioner [United States and Other]
  20. Find An AMS Doctor [Australasian Menopause Society i.e. Australia and New Zealand]
  21. Find Your Nearest BMS Menopause Specialist [British Menopause Society]
  22. HRT
  23. HRT and Alternatives
  24. HRT and Breast Cancer: Overall Risks and Benefits Explained – A British Menopause Society Video
  25. HRT and the Risk of Breast Cancer Explained – A British Menopause Society Video
  26. HRT: Benefits and Risks
  27. HRT: Types, Doses and Regimens
  28. Health After Menopause
  29. Hormone Replacement Therapy
  30. Hormone Replacement Therapy (HRT)
  31. Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
  32. Hormone Therapy In Postmenopausal Women: Primary Prevention of Chronic Conditions
  33. Hormone Therapy: Is It Right for You?
  34. Hot Flashes: Manage Without Medication?
  35. How To Prevent Osteoporosis After Menopause
  36. International Menopause Society Statement – Use of Postmenopausal Hormone Therapy and Risk of Alzheimer’s Disease In Finland: Nationwide Case-Control Study
  37. Is It Too Late To Start HRT At 60? – Ask Dr Jean
  38. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health
  39. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – The Menopause: Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?]
  40. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Signs and Symptoms [+ Video: Talking Menopause With Your GP]
  41. Learning To Cope With Hot Flashes
  42. Lifestyle and Behavioural Modifications for Menopausal Symptoms
  43. Maintaining Your Weight and Health During and After Menopause
  44. Making Choices At Menopause
  45. Managing Menopausal Symptoms—Hormone Replacement Therapy Is Not the Only Option!
  46. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video]
  47. Mayo Clinic Minute: How Lifestyle Changes May Help Manage Menopause Symptoms [+ Video]
  48. Menopausal Hormone Therapy
  49. Menopausal Hormone Therapy and Breast Cancer Risk
  50. Menopausal Hormone Therapy and Venous Thromboembolism
  51. Menopausal Hormone Therapy, Heart Disease and Stroke
  52. Menopause
  53. Menopause
  54. Menopause
  55. Menopause Explained – A British Menopause Society Video
  56. Menopause Hormone Therapy and Your Heart
  57. Menopause Hormone Therapy: Follow-Up Appointments?
  58. Menopause Hormone Therapy: Who Shouldn’t Take It?
  59. Menopause Management: Menopausal Hormone Therapy (MHT)
  60. Menopause Map: Downloadable Resources – Stages of Menopause: Postmenopause
  61. Menopause Symptoms and Relief
  62. Menopause: Diagnosis & Treatment
  63. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  64. Menopause: Is Menopausal Hormone Therapy (HRT) Safe? [Multiply Languages] [Video]
  65. Menopause: Medicines To Help You
  66. Menopause: Menopause – Hormone Treatments
  67. Menopause: Non-Hormonal Treatment & Relief for Hot Flashes
  68. Menopause: What Is Menopausal Hormone Therapy (HRT)? [Multiply Languages] [Video]
  69. NAMS 2017 Position Statement Updates Guidelines for Hormone Therapy Use
  70. National Center for Complementary and Integrative Health: Herbs At A Glance
  71. National Center for Complementary and Integrative Health: How Safe Is This Product or Practice?
  72. National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
  73. Non-Estrogen Treatments for Menopausal Symptoms
  74. NonHormonal Treatments for Menopausal Symptoms
  75. Oestrogen Only Menopausal Hormone Therapy
  76. Postmenopause
  77. Risks and Benefits of MHT
  78. SERMs – Their Role In Menopause Management
  79. Starting and Stopping, Duration of Menopause Hormone Therapy Use
  80. The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience”
  81. The Menopause: After the Menopause
  82. The North American Menopause Society Statement on Continuing Use of Systemic Hormone Therapy After Age 65
  83. Tibolone As Menopausal Hormone Therapy
  84. Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta Analysis of the Worldwide Epidemiological Evidence [29 August 2019]
  85. Types of Hormone Therapy
  86. Update on Hormone Therapy for the Management of Postmenopausal Women
  87. Video Series-2021: Treatment Options for Vaginal Dryness and Urinary Issues
  88. Video Series-2021: What Women Need To Know About Hormone Therapies
  89. Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
  90. Video Series-2022: Understanding Screening Guidelines for Breast Cancer and the Importance of Identifying Risk Factors
  91. Videos and Podcasts: Interviews and Podcasts – Interviews: Menopause More Than Hot Flashes
  92. Videos and Podcasts: Interviews and Podcasts – Interviews: Prevention of Chronic Diseases In Women: Where Does MHT Fit In?
  93. Videos and Podcasts: World Menopause Day 2021 – Interviews: Bone Health What Why and How
  94. Webinars: Previous – Primary Prevention of Cardiovascular Disease With MHT: Where Are We Now?
  95. Webinars: Previous – The Early Menopausal Patient
  96. What Are the Benefits and Risks of HRT?
  97. What Can I Do To Help With Hot Flashes?
  98. What Is Menopausal Hormone Therapy (MHT) and Is It Safe?
  99. Women’s Wellness: Hot Flashes and Night Sweats Happen After Menopause [+ Video Courtesy: Mayo Clinic News Network
  100. Women’s Wellness: Mindfulness May Ease Menopausal Symptoms

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/hrt-2013-06-english.pdf Accessed: 10 May 2022
  2. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/hrt-2013-06-english.pdf Accessed: 10 May 2022
  3. Glossary: V – Vasomotor Symptoms. North American Menopause Society http://www.menopause.org/for-women/menopause-glossary#V Accessed: 10 May 2022
  4. The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience”. 29 August 2019:1. International Menopause Society https://www.imsociety.org/wp-content/uploads/2020/07/ims-press-statement-2019-08-29-english.pdf Accessed: 10 May 2022
  5. The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience”. 29 August 2019:2. International Menopause Society https://www.imsociety.org/wp-content/uploads/2020/07/ims-press-statement-2019-08-29-english.pdf Accessed: 10 May 2022
  6. Menopause Experts Dismiss Some Breast Cancer Claims In New Report. 30 August 2019. Jean Hailes for Women’s Health https://jeanhailes.org.au/news/menopause-experts-dismiss-breast-cancer-claims-of-new-report Accessed: 10 May 2022
  7. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 10 May 2022
  8. NAMS 2017 Position Statement Updates Guidelines for Hormone Therapy Use. 20 June 2017:1. North American Menopause Society https://www.menopause.org/docs/default-source/default-document-library/ht-press-release-061917.pdf Accessed: 10 May 2022
  9. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT. Climacteric, 2016;19:4:314 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 10 May 2022

Topic Last Updated: 17 June 2022– Topic Last Reviewed: 10 May 2022
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