Hormone Therapy Postmenopause

Hormone therapy postmenopause “benefits are more likely to outweigh risks if initiated for symptomatic women before the age of 60 years or within 10 years after menopause”.1

Umbrella
What may the Hormone Therapy Postmenopause Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT) After Menopause
  • Hormone Therapy (HT) After Menopause
  • Menopausal Hormone Therapy (MHT) After Menopause
  • Postmenopausal/Postmenopause Hormone Replacement Therapy (HRT)/Hormone Therapy (HT)

Revised Global Consensus Statement

What is one of the points of consensus about menopausal hormone therapy (MHT) and postmenopause?

One of the points of consensus in the Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT – endorsed by seven menopause-related organizations – published online 20 June 2016, is:

Hormone Therapy Benefits and Risks

  • “MHT, including tibolone and the combination of conjugated equine estrogens and bazedoxifene (CE/BZA), is the most effective treatment for vasomotor symptoms (VMS) associated with menopause at any age, but benefits are more likely to outweigh risks if initiated for symptomatic women before the age of 60 years or within 10 years after menopause”.2

What are vasomotor symptoms?

DotS the definition of vasomotor symptoms may vary. The North American Menopause Society’s definition is:

“Vasomotor symptoms. Also known as hot flashes and night sweats, common symptoms during perimenopause and early postmenopause”.3

Type and Timing of Menopausal Hormone Therapy and… Meta-Analysis

Hormone Therapy and Breast CancerHormone Therapy and Breast CancerWhat has feedback included about Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Evidence, published in the Lancet on 29 August 2019?

On page one in The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience” the IMS elaborate on:

“Is there new information that menopausal hormone therapy (MHT) substantially increases breast cancer risk as suggested by a paper published in the Lancet this month and should women be worried?

  • Much of the information regarding breast cancer risk and MHT reported in this paper is not new…
  • It is important to note that, because of when the data included in this report was collected, most of the MHT regimes were different from those used today
  • This paper provides an important public health message about obesity and breast cancer risk…”.4

What do the IMS recommend?

On page two in The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience” the IMS explain:

“Recommendations From the IMS

Women enter menopause across a range of ages, with diverse symptoms and health risk profiles. The International Menopause Society advocates the comprehensive assessment of women, including attention to modifying risk factors for chronic disease such as being overweight or obese, the importance of which have been highlighted in this Lancet paper. The benefits and risks of MHT differ according to the timing of menopause such that individualisation of therapy is essential. As prescribing practices have changed significantly over the last decade, further research is needed to determine the impact of currently recommended regimens”.5

In Menopause Experts Dismiss Some Breast Cancer Claims In New Report the (Australian) Jean Hailes for Women’s Health elaborate on:

“Australian menopause experts are urging women to talk to their doctor about their use of menopausal hormone therapy (MHT) if they have concerns following today’s publication of a large study linking MHT to an increased risk of breast cancer”.6

Where may I find Links related to Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta Analysis of the Worldwide Epidemiological Evidence, published in the Lancet on 29 August 2019?

Your Country may have Links similar to:

Links

This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.

  1. BMJ Editorial: HRT and Breast Cancer Risk: We Must Prevent Another Setback In Women’s Health [14 October 2019] [British Medical Journal]
  2. BMS Response To Lancet Paper on the Link Between Different Forms of HRT and Breast Cancer Incidence [30 August 2019]
  3. BMS Response To MHRA Recommendations [09 September 2019]
  4. Experts Debate New Analysis Concerning Breast Cancer Risk With Menopausal HT [06 September 2019]
  5. Experts Rip Into HRT-Cancer Study: From the Medical Republic – 9 September 2019
  6. HRT and Breast Cancer Statement In Response To EMA Pharmacovigilance Risk Assessment Committee Recommendations In May 2020 [14 September 2020]
  7. Joint RCOG & BMS Statement In Response To the Lancet Study on HRT Use and Breast Cancer Risk [30 August 2019]
  8. MHT and Breast Cancer Risk
  9. Making Sense of Menopausal Hormone Therapy Means Understanding the Benefits As Well As the Risks [18 November 2019]
  10. Menopausal Hormone Therapy Regimens Have Opposite Lasting Effects on Breast Cancer Incidence [13 December 2019]
  11. Menopause Experts Dismiss Some Breast Cancer Claims In New Report [30 August 2019]
  12. Menopause Matters [September 2019]
  13. Menopause: Diagnosis and Management – Information for the Public: Benefits and Risks of HRT – Breast Cancer [05 December 2019] [NICE Guideline]
  14. Resources / Podcasts: Menopause and Hormone Replacement Therapy (HRT) [21 October 2019]
  15. Resources / Webinar: The Breast Cancer and MHT Controversy – An Expert Panel Separates Fact From Fiction [15 November 2019]
  16. Response From MHRA/FOI [25 October 2019]
  17. Risks and Benefits of MHT/HRT [May 2019]
  18. The Breast Cancer and MHT Controversy [Video]
  19. The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience” [29 August 2019]
  20. Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta Analysis of the Worldwide Epidemiological Evidence [29 August 2019]
  21. We Don’t Know Menopausal Hormone Therapy Causes Breast Cancer, But the Evidence Continues To Suggest A Link [03 September 2019]
  22. Women’s Wellness: Does Menopausal Hormone Therapy Increase Risk of Breast Cancer? [30 August 2019]

Postmenopausal Bone Health

What are some points of consensus about MHT and postmenopausal bone health?

Some points of consensus in the Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT are:

  • “MHT, including tibolone and CE/BZA, is effective in the prevention of bone loss in postmenopausal women
  • MHT has been shown to significantly lower the risk of hip, vertebral and other osteoporosis-related fractures in postmenopausal women
  • MHT, including tibolone, can be initiated in postmenopausal women at risk of fracture or osteoporosis before the age of 60 years or within 10 years after menopause”.7


What is CE/BZA?

CE/BZA can be an abbreviation for Conjugated Equine Estrogens/Bazedoxifene.

Over Age 60

If I am postmenopausal and over aged 60 years, do I need to stop hormone therapy (HT)?

On page one in the NAMS 2017 Position Statement Updates Guidelines for Hormone Therapy Use the North American Menopause Society note:

  • “For women who initiate HT more than 10 or 20 years from menopause onset or when aged 60 years or older, the benefit-risk ratio appears less favorable than for younger women because of greater absolute risks of coronary heart disease, stroke, venous thromboembolism, and dementia
  • Hormone therapy does not need to be routinely discontinued in women aged older than 60 or 65 years and can be considered for continuation beyond age 65 years for persistent hot flashes, quality-of-life issues, or prevention of osteoporosis after appropriate evaluation and counseling of benefits and risks”.8

Health Care Provider

What if I am postmenopausal and choose to use HT?

If you are postmenopausal and choose to use HT, it may be in your best interest to also choose to talk to your health care provider about this.

One of the points of consensus in the Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT is:

  • “The option of MHT is an individual decision in terms of quality of life and health priorities as well as personal risk factors such as age, time since menopause and the risk of VTE, stroke, ischemic heart disease and breast cancer. MHT should not be recommended without a clear indication for its use”.9

Health Topics A-Z

Where may I find Health Topics related to Hormone Therapy Postmenopause?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy Postmenopause?

Your Country may have Links similar to:

Links

This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.

  1. 9 Myths and Misunderstandings About Menopausal Hormone Therapy (MHT): 6. Myth – Complementary Medicines and Therapies Are As Effective As MHT and Safer
  2. 9 Myths and Misunderstandings About Menopausal Hormone Therapy (MHT): 7. Myth – Compounded Bioidentical Hormone Therapy Is Safer Than Conventional MHT
  3. Archives: Videos – Managing Menopause In Women With Chronic Medical Conditions
  4. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  5. Bioidentical Hormone Therapy
  6. Bioidentical Hormones Explained – A British Menopause Society Video
  7. Bioidentical Hormones: Are They Safer?
  8. ClinicalTrials.gov: Postmenopause Hormone Replacement Therapy
  9. ClinicalTrials.gov: Postmenopause Hormone Therapy
  10. ClinicalTrials.gov: Postmenopause Menopausal Hormone Therapy
  11. Cognitive Behaviour Therapy (CBT) for Menopausal Symptoms
  12. Combined Menopausal Hormone Therapy (MHT)
  13. Complementary Medicine Options for Menopausal Symptoms
  14. Complementary and Alternative Therapies Explained – A British Menopause Society Video
  15. Compounded Bioidentical Hormone Therapy [Video]
  16. Consumer Health: Menopause, Hormone Replacement Therapy and Heart Health
  17. Coronary Heart Disease (CHD) Explained – A British Menopause Society Video
  18. Deciding About Hormone Therapy
  19. Deciding About Hormone Therapy Use
  20. Does Hormone Replacement Therapy Increase Cancer Risk?
  21. Early Menopause: Experiences and Perspectives of Women and Health Practitioners
  22. Early Menopause: Experiences and Perspectives of Women and Health Practitioners – Women’s Profiles
  23. HRT
  24. HRT and Alternatives
  25. HRT and Breast Cancer: Overall Risks and Benefits Explained – A British Menopause Society Video
  26. HRT and the Risk of Breast Cancer Explained – A British Menopause Society Video
  27. HRT: Benefits and Risks
  28. Health After Menopause
  29. Hormone Replacement Therapy
  30. Hormone Replacement Therapy (HRT)
  31. Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
  32. Hormone Therapy In Postmenopausal Women: Primary Prevention of Chronic Conditions
  33. Hormone Therapy: Is It Right for You?
  34. Hot Flashes: Manage Without Medication?
  35. Information About Menopause [Multiply Languages] [Videos]
  36. International Menopause Society Statement – Use of Postmenopausal Hormone Therapy and Risk of Alzheimer’s Disease In Finland: Nationwide Case-Control Study
  37. Is It Too Late To Start HRT At 60? – Ask Dr Jean
  38. Learning To Cope With Hot Flashes
  39. Lifestyle and Behaviour Changes for Menopausal Symptoms
  40. Lifestyle and Behavioural Modifications for Menopausal Symptoms
  41. Maintaining Your Weight and Health During and After Menopause
  42. Making Choices At Menopause
  43. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video Courtesy: Mayo Clinic News Network]
  44. Mayo Clinic Minute: Lifestyle Changes To Manage Menopause Symptoms [+ Video Courtesy: Mayo Clinic News Network]
  45. Mayo Clinic Minute: What Is Heart Disease?
  46. Menopause
  47. Menopause
  48. Menopause
  49. Menopause Explained – A British Menopause Society Video
  50. Menopause FAQs: Hormone Therapy for Menopause Symptoms
  51. Menopause FAQs: Hot Flashes
  52. Menopause FAQs: Your Health After Menopause
  53. Menopause Hormone Therapy and Your Heart
  54. Menopause Hormone Therapy: Follow-Up Appointments?
  55. Menopause Hormone Therapy: Who Shouldn’t Take It?
  56. Menopause Management: Menopausal Hormone Therapy (MHT)
  57. Menopause Symptoms and Relief
  58. Menopause Treatment
  59. Menopause – Complementary Therapies [Multiply Languages] [Video]
  60. Menopause – How Will It Affect My Health [Multiply Languages] [Video]
  61. Menopause – Is Menopausal Hormone Therapy (HRT) Safe? [Multiply Languages] [Video]
  62. Menopause – Non-Hormonal Treatment Options [Multiply Languages] [Video]
  63. Menopause – What Is Menopausal Hormone Therapy (HRT)? [Multiply Languages] [Video]
  64. Menopause: Diagnosis & Treatment
  65. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  66. Menopause: Hormone Replacement Therapy (HRT) [Video Interview Stories]
  67. Menopause: Medicines To Help You
  68. Menopause: Menopause – Hormone Treatments
  69. Menopause: Non-HRT and Lifestyle Options [Video Interview Stories]
  70. Menopause: Non-Hormonal Treatment & Relief for Hot Flashes
  71. Menopause: Profiles – Postmenopausal [Video Interview Stories]
  72. NAMS 2017 Position Statement Updates Guidelines for Hormone Therapy Use
  73. NAMS Supports Judicious Use of Systemic Hormone Therapy for Women Aged 65 Years and Older
  74. National Center for Complementary and Integrative Health: Herbs At A Glance
  75. National Center for Complementary and Integrative Health: How Safe Is This Product or Practice?
  76. National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
  77. Non-Hormonal Treatment Options for Menopausal Symptoms
  78. NonHormonal Treatments for Menopausal Symptoms
  79. Oestrogen Only Menopausal Hormone Therapy
  80. Risks and Benefits of MHT
  81. SERMs – Their Role In Menopause Management
  82. The North American Menopause Society Statement on Continuing Use of Systemic Hormone Therapy After Age 65
  83. Tibolone As Menopausal Hormone Therapy
  84. Types of Hormone Therapy
  85. Urogenital Atrophy Explained – A British Menopause Society Video
  86. Vaginal Dryness
  87. Vaginal Dryness
  88. Video Series-2020 – Bone Health What You Need To Know
  89. Video Series-2020 – TSECs—A New Treatment for Hot Flashes and Night Sweats
  90. Video Series-2021 – Treatment Options for Vaginal Dryness and Urinary Issues
  91. Video Series-2021 – What Women Need To Know About Hormone Therapies
  92. Video Series-2021 – What You Need to Know About the #1 Cause of Death in Women
  93. Webinars: Other Webinars – Progestogen, Progestin, Progesterone: Why All the Confusion?
  94. Webinars: Symposia – 2021 Vision: Practical Steps to Optimize Your Benefit-Risk. Discussions for A New Decade
  95. What Can I Do To Help With Hot Flashes?
  96. What Is Menopausal Hormone Therapy (MHT) and Is It Safe?
  97. Women’s Wellness: Hot Flashes and Night Sweats Happen After Menopause [+ Video Courtesy: Mayo Clinic News Network
  98. What Is MHT and Is It Safe? Women’s Wellness: Mindfulness May Ease Menopausal Symptoms
  99. Women’s Wellness: Painful Sex After Menopause
  100. Women’s Wellness: Treating Hot Flashes and Night Sweats Without Hormones [+ Video]

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/hrt-2013-06-english.pdf Accessed: 30 July 2021
  2. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/hrt-2013-06-english.pdf Accessed: 30 July 2021
  3. Glossary: V – Vasomotor Symptoms. North American Menopause Society http://www.menopause.org/for-women/menopause-glossary#V Accessed: 30 July 2021
  4. The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience”. 29 August 2019:1. International Menopause Society https://www.imsociety.org/wp-content/uploads/2020/07/ims-press-statement-2019-08-29-english.pdf Accessed: 30 July 2021
  5. The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience”. 29 August 2019:2. International Menopause Society https://www.imsociety.org/wp-content/uploads/2020/07/ims-press-statement-2019-08-29-english.pdf Accessed: 30 July 2021
  6. Menopause Experts Dismiss Some Breast Cancer Claims In New Report. 30 August 2019. Jean Hailes for Women’s Health https://jeanhailes.org.au/news/menopause-experts-dismiss-breast-cancer-claims-of-new-report Accessed: 30 July 2021
  7. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 30 July 2021
  8. NAMS 2017 Position Statement Updates Guidelines for Hormone Therapy Use. 20 June 2017:1. North American Menopause Society https://www.menopause.org/docs/default-source/default-document-library/ht-press-release-061917.pdf Accessed: 30 July 2021
  9. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT. Climacteric, 2016;19:4:314 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 30 July 2021

Topic Last Updated: 30 July 2021 – Topic Last Reviewed: 30 July 2021
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