“Current evidence suggests that oestrogen alone HRT
is associated with a lower risk of breast cancer
than combined HRT”.1
Umbrella
What may the Hormone Therapy and Breast Cancer Umbrella include?
Depending on the Source (DotS) this Umbrella may include:
- Breast Cancer
- Cancer of the Breast
- Hormone Replacement Therapy (HRT)
- Hormone Therapy (HT)
- Menopausal Hormone Therapy (MHT)
Different Differences
What is it important to understand about hormone therapy (HT) and breast cancer risk?
On page three Menopausal Hormone Therapy (MHT) for the Management of Menopausal Symptoms: Position Statement – The Jean Hailes Position: JH Notes the Following Evidence – 6b) Breast Cancer dated 07 April 2020, the (Australian) Jean Hailes for Women’s Health elaborate on:
- “The level of increased breast cancer risk with MHT use varies, according to which data is analysed. It is not possible to estimate an overall absolute risk of breast cancer by combining and examining all the available MHT research. Research studies may look at different types of MHT, different doses, different ages of women, different age of treatment initiation, different duration of use of MHT. All these factors may influence risk”.2
Breast Cancer Risk
What is known about HT and breast cancer risk?
On page two and three in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:
In Menopausal Hormone Therapy and Breast Cancer Risk: Summary of Findings, published 2022, the European Menopause and Andropause Society (EMAS) explain:
- “Estrogen-alone systemic menopausal hormone therapy does not significantly increase and may even reduce breast cancer risk.
- Low-dose topical estrogen does not increase breast cancer risk.
- Combined menopausal hormone therapy confers a small increased risk but this decreases after treatment is stopped.
- Risk differs according to the progestogen used, being higher with medroxyprogesterone acetate, levonorgestrel and norethisterone and lower with dydrogesterone and progesterone.
- Breast cancer risk has to be put into clinical perspective, with account taken of other risk factors”.4
Uterus
If a woman has a uterus and chooses to use estrogen plus progestogen therapy, what is her breast cancer risk?
On page one in Deciding About Hormone Therapy Use: Potential Risks published June 2022, according to the North American Menopause Society (NAMS):
No Uterus
If a woman does not have a uterus and chooses to use estrogen therapy, what is her breast cancer risk?
On page one in Deciding About Hormone Therapy Use: Potential Risks published June 2022, the NAMS explain:
Risk Comparison
What puts a woman at a higher risk of developing breast cancer than taking HRT?
In Menopausal Hormone Therapy and Breast Cancer Risk: Summary of Findings the EMAS note:
- “Regular alcohol consumption, obesity and physical inactivity increase the risk of breast cancer by 32–46%, 26–152%, and 7–33% respectively. This is much higher than the risk conferred by menopausal hormone therapy”.7
In Does Hormone Replacement Therapy Increase Cancer Risk? Should I Take HRT? Cancer Research UK explain:
Breast Cancer Screening
If a woman chooses to use HT, what is important about breast cancer screening?
In Hormone Replacement Therapy (HRT): Risks – Breast Cancer the (United Kingdom) NHS note:
At High Risk of Breast Cancer
Is HT recommended for those at high risk of breast cancer?
In Making Decisions About Hormone Replacement Therapy last updated on 30 June 2022, the (United States) Breastcancer.org explain:
Breast Cancer Patients
Is HT recommended for women who have been diagnosed with breast cancer?
In Making Decisions About Hormone Replacement Therapy last updated on 30 June 2022, Breastcancer.org elaborate on:
On page three in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:
Hormone Receptor-Negative Breast Cancer Patients
Can hormone receptor-negative (HR-) breast cancer patients take HT?
In Making Decisions About Hormone Replacement Therapy last updated on 30 June 2022, Breastcancer.org explain:
Health Care Provider
If I choose to use HT how can I follow up?
The (United States) Mayo Clinic note:
- “Seek regular follow-up care. See your doctor regularly to ensure that the benefits of hormone therapy continue to outweigh the risks, and for screenings such as mammograms and pelvic exams”.14
Health Topics A-Z
Where may I find Health Topics related to Hormone Therapy and Breast Cancer?
In Health Topics A-Z you may find:
Links
Where may I find Links related to Hormone Therapy and Breast Cancer?
Your Country may have Links similar to:
Links
This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.New or Updated
- 20 Years of Data Lead To Changes In Perceptions, Usage of Menopausal HT
- 9 Myths and Misunderstandings About Menopausal Hormone Therapy (MHT)
- Askearlymenopause.org [Ask EM] [+ Video: What Is Early Menopause?]
- Association of Menopausal Hormone Therapy With Breast Cancer Incidence and Mortality During Long-Term Follow-Up of the Women’s Health Initiative Randomized Clinical Trials
- BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
- Bioidentical Hormones Explained – A British Menopause Society Video
- Bioidentical Hormones: Are They Safer?
- Breast Cancer
- Breast Cancer Risk Associated With HRT Increases With Longer Use, Finds Study
- Breast Cancer: Risk Factors
- Breastcancer.org
- Breastcancernow.org
- Cognitive Behaviour Therapy (CBT) for Menopausal Symptoms
- Combined Menopausal Hormone Therapy (MHT)
- Complementary and Alternative Therapies Explained – A British Menopause Society Video
- Compounded Bioidentical Hormone Therapy [Video]
- Deciding About Hormone Therapy
- Deciding About Hormone Therapy Use
- Dr Gail Busby – I Forgot To Ask the Doctor – Episode 9 The Menopause
- Dr. Lisa Larkin – Breast Health Made Personal
- Estrogen Dependent Cancers
- Estrogen Therapy and Breast Cancer In Randomized Clinical Trials: A Narrative Review
- Find A Menopause Practitioner [United States and Other]
- Find An AMS Doctor [Australasian Menopause Society i.e. Australia and New Zealand]
- Find Your Nearest BMS Menopause Specialist [British Menopause Society]
- HRT & Menopause Extra
- HRT and Breast Cancer Statement In Response To EMA Pharmacovigilance Risk Assessment Committee Recommendations In May 2020
- HRT and Breast Cancer: Overall Risks and Benefits Explained – A British Menopause Society Video
- HRT and the Risk of Breast Cancer Explained – A British Menopause Society Video
- HRT – Types, Doses and Regimens
- HRT: Benefits and Risks
- HRT: The History
- Hormone Replacement Therapy
- Hormone Replacement Therapy (HRT)
- Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
- Hormone Replacement Therapy (HRT) With Dr Nicky Peel & Prof. David Armstrong
- Hormone Replacement Therapy (HRT): Benefits and Risks
- Hormone Replacement Therapy (HRT): Types
- Hormone Therapy: Is It Right for You?
- Hot Flashes
- Hot Flashes
- Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
- How To Find Relief for Hot Flashes At Night
- Jean Hailes MHT Position Statement
- Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
- Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?]
- MHT Still Maligned & Misunderstood: Expert
- MHT and Breast Cancer Risk
- MHT and Breast Cancer – Risk Even Lower, Study Reports
- Making Decisions About Hormone Replacement Therapy
- Making Sense of Menopausal Hormone Therapy Means Understanding the Benefits As Well As the Risks
- Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video Courtesy: Mayo Clinic News Network]
- Mayo Clinic Minute: How Lifestyle Changes May Help Manage Menopause Symptoms [+ Video]
- Menopausal Hormone Therapy (MHT) for the Management of Menopausal Symptoms: Position Statement
- Menopausal Hormone Therapy Regimens Have Opposite Lasting Effects on Breast Cancer Incidence
- Menopausal Hormone Therapy and Breast Cancer Risk
- Menopausal Hormone Therapy and Breast Cancer Risk: Individualization Is the Key To Safety
- Menopausal Hormone Therapy and Cancer
- Menopausal Hormone Therapy and Long-Term Breast Cancer Risk: Further Data From the Women’s Health Initiative Trials
- Menopausal Hormone Therapy: Why We Should No Longer Be Afraid of the Breast Cancer Risk
- Menopause
- Menopause
- Menopause Experts Dismiss Some Breast Cancer Claims In New Report
- Menopause Management Options: Menopausal Hormone Therapy (MHT)
- Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
- Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
- Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
- Menopause Patient Information [Videos] 4. The Different Types of HRT
- Menopause Preparedness Toolkit Video Series: Treating Vasomotor Symptoms of Menopause
- Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
- Menopause Treatments: What Works, What Doesn’t
- Menopause: Diagnosis & Treatment
- Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
- National Center for Complementary and Integrative Health: Cancer In-Depth
- National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
- Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
- Oestrogen Only Menopausal Hormone Therapy
- Optimising the Menopause Transition: Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
- Risks and Benefits of MHT
- Systemic or Vaginal Hormone Therapy After Early Breast Cancer: A Danish Observational Cohort Study
- The IMS Has Released A Statement: Use of Hormone Replacement Therapy (HRT) and Risk of Breast Cancer
- The International Menopause Society Comment on: “Type and Timing of Menopausal Hormone Therapy and Breast Cancer Risk: Individual Participant Meta-Analysis of the Worldwide Epidemiological Experience”
- The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement
- The Women’s Health Initiative Randomized Trials of Menopausal Hormone Therapy and Breast Cancer: Findings In Context
- Tips To Help Manage Menopause Symptoms
- Types of Hormone Therapy
- Understanding Breast Cancer Risk
- Understanding Hormone Replacement Therapy
- Using HRT (Hormone Replacement Therapy)
- Using Natural Therapies In the Menopause Transition – Webinar
- Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
- Video Series-2022: Understanding Screening Guidelines for Breast Cancer and the Importance of Identifying Risk Factors
- Video Series-2023: Lifestyle Modification and Prevention of Breast Cancer
- Videos and Podcasts: Videos – Interviews: Scientific Advances In Early Cancer Detection. What the Future Holds
- Videos and Podcasts: Videos – Interviews: The Women’s Health Initiative – What Can We Believe?
- Webinars: Previous – Breast Cancer
- Webinars: Previous – The Early Menopausal Patient
- What Are the Benefits and Risks of HRT?
- Why Didn’t Anyone Tell Me This? Episode 3: Dr Annice Mukherjee: Your Essential Menopause Toolkit
- Why We Don’t Have Good Evidence To Show That HRT Is Safe After Breast Cancer [Video]
Sources
Where may I find the Sources quoted?
You may find the Sources quoted at:
Sources
- Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2-3. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 22 March 2023
- Menopausal Hormone Therapy (MHT) for the Management of Menopausal Symptoms: Position Statement – The Jean Hailes Position: JH Notes the Following Evidence – 6b) Breast Cancer. 07 April 2020:3. Jean Hailes for Women’s Health. https://assets.jeanhailes.org.au/JH_position-statement_MHT.pdf Accessed: 22 March 2023
- Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2-3. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 22 March 2023
- Menopausal Hormone Therapy and Breast Cancer Risk: Summary of Findings. 2022 European Menopause and Andropause Society https://emas-online.org/wp-content/uploads/2022/05/Menopausal-hormone-therapy-and-breast-cancer-risk.pdf Accessed: 22 March 2023
- Deciding About Hormone Therapy Use: Potential Risks. 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 22 March 2023
- Deciding About Hormone Therapy Use: Potential Risks. 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 22 March 2023
- Menopausal Hormone Therapy and Breast Cancer Risk: Summary of Findings. 2022 European Menopause and Andropause Society https://emas-online.org/wp-content/uploads/2022/05/Menopausal-hormone-therapy-and-breast-cancer-risk.pdf Accessed: 22 March 2023
- Does Hormone Replacement Therapy Increase Cancer Risk? Should I Take HRT? Last Reviewed: 09 March 2021. Research UK https://www.cancerresearchuk.org/about-cancer/causes-of-cancer/hormones-and-cancer/does-hormone-replacement-therapy-increase-cancer-risk#breast Accessed: 22 March 2023
- Hormone Replacement Therapy (HRT): Risks – Breast Cancer. Page Last Reviewed: 09 September 2019. NHS https://www.nhs.uk/conditions/hormone-replacement-therapy-hrt/risks/#breast-cancer Accessed: 22 March 2023
- Making Decisions About Hormone Replacement Therapy. Last Updated on: 30 June 2022. Breastcancer.org https://www.breastcancer.org/tips/menopausal/hrt/decisions Accessed: 22 March 2023
- Making Decisions About Hormone Replacement Therapy. Last Updated on: 30 June 2022. Breastcancer.org https://www.breastcancer.org/tips/menopausal/hrt/decisions Accessed: 22 March 2023
- Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:3-4. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 22 March 2023
- Making Decisions About Hormone Replacement Therapy. Last Updated on: 30 June 2022. Breastcancer.org https://www.breastcancer.org/tips/menopausal/hrt/decisions Accessed: 22 March 2023
- Hormone Therapy: Is It Right for You? Who Can Benefit From Hormone Therapy? If You Take Hormone Therapy, How Can You Reduce Risk? 06 December 2022. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/menopause/in-depth/hormone-therapy/art-20046372 Accessed: 22 March 2023