“The Women’s Health Initiative (WHI)
is a long-term national health study funded by the
National Heart, Lung, and Blood Institute, or NHLBI”.1

Date

What can it be important to be clear about with hormone therapy (HT) information?

It can be important to be clear about the date of all information including the date of HT information, because this information may have been updated.

Symptoms or Chronic Conditions

What can it also be important to be clear about with HT information?

It can also be important to be clear about whether HT information is about the use of HT for the management of menopausal symptoms such as hot flushes, night sweats and vaginal dryness; or for the prevention of chronic conditions such as cardiovascular disease, cancers, and osteoporotic fractures.

Women’s Health Initiative

What is the (United States) Women’s Health Initiative (WHI)?

In About WHI the WHI elaborate on:

“The Women’s Health Initiative (WHI) is a long-term national health study funded by the National Heart, Lung, and Blood Institute, or NHLBI”.2

Goal

What is the goal of the WHI?

In Women’s Health Initiative (WHI): What Is the Goal of the WHI? the (United States) National Heart, Lung, and Blood Institute (NHLBI) explain:

“The Women’s Health Initiative (WHI), sponsored by the National Heart, Lung, and Blood Institute (NHLBI), is a long-term national health study that focuses on strategies for preventing heart disease, breast and colorectal cancer, and osteoporosis in postmenopausal women. These chronic diseases are the major causes of death, disability, and frailty in older women of all races and socioeconomic backgrounds”.3

Original WHI Study Dates

When was the original WHI study?

In About WHI the WHI note:

“The original WHI study began in the early 1990s and concluded in 2005”.4

Original WHI Study

In the original WHI study, what were the three parts?

In Women’s Health Initiative (WHI): What Is the Goal of the WHI? the NHLBI explain:

“The original WHI study had three parts—a clinical trial, an observational study, and a community prevention study—and completed data collection in 2005”.5

Expectations

What did the WHI’s researchers expect to find in their two studies in the hormone trial?

On page one in the NAMS Journal Menopause Reflects on the WHI Ten Years Later the North American Menopause Society explain:

“Researchers expected to find that hormones prevented chronic conditions of aging in women, including heart disease. Instead, they found that hormones produced a mix of risks and benefits”.6

Heart Disease

What did the WHI find about hormone replacement therapy and heart disease?

In Women’s Health Initiative (WHI): At A Glance the NHLBI note:


Women’s Health Initiative

  • “The WHI found that hormone replacement therapy did not prevent heart disease in postmenopausal women as once thought”.7

Extension Studies

What are the WHI’s extension studies?

In About WHI the WHI explain:

“Since 2005, the WHI has continued as Extension Studies, which are annual collections of health updates and outcomes in active participants. The second Extension Study enrolled 93,500 women in 2010 and follow-up of these women continues annually”.8

Extension Studies Main Areas of Research

What are the extension studies main areas of research?

In About WHI the WHI elaborate on:

“As with the original WHI study, the main areas of research are cardiovascular disease, cancers, and osteoporotic fractures. While WHI continues to focus on strategies to prevent the major causes of death, disability, and frailty in older women, the breadth and richness of the WHI data allow for the exploration and investigation of many more research questions on women’s health and aging”.9

Health Care Provider

What if I choose to use HT?

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement, published 07 July 2022 and “endorsed by more than 20 well-respected international organizations”, the North American Menopause Society note:

“Highlights from the NAMS 2022 Hormone Therapy Position Statement include:

  • “Hormone therapy remains the most effective treatment for vasomotor symptoms (VMS) and the genitourinary syndrome of menopause (GSM) and has been shown to prevent bone loss and fracture”.10

Health Topics A-Z

Where may I find Health Topics related to the Women’s Health Initiative?

In Health Topics A-Z you may find:

Links

Where may I find Links related to Women’s Health Initiative?

Your Country may have Links similar to:

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. About WHI. Women’s Health Initiative https://www.whi.org/about-whi Accessed: 26 November 2022
  2. About WHI. Women’s Health Initiative https://www.whi.org/about-whi Accessed: 26 November 2022
  3. Women’s Health Initiative (WHI): What Is the Goal of the WHI? National Heart, Lung, and Blood Institute https://www.whi.org/page/about-whi Accessed: 26 November 2022
  4. About WHI. Women’s Health Initiative https://www.whi.org/about-whi Accessed: 26 November 2022
  5. Women’s Health Initiative (WHI): What Is the Goal of the WHI? National Heart, Lung, and Blood Institute https://www.whi.org/page/about-whi Accessed: 26 November 2022
  6. NAMS Journal Menopause Reflects on the WHI Ten Years Later. 29 May 2012:1. North American Menopause Society https://www.menopause.org/docs/default-document-library/pr12whi.pdf?sfvrsn=2 Accessed: 26 November 2022
  7. Women’s Health Initiative (WHI): At A Glance. National Heart, Lung, and Blood Institute https://www.whi.org/page/about-whi Accessed: 26 November 2022
  8. About WHI. Women’s Health Initiative https://www.whi.org/about-whi Accessed: 26 November 2022
  9. About WHI. Women’s Health Initiative https://www.whi.org/about-whi Accessed: 26 November 2022
  10. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 26 November 2022
Topic Last Updated: 26 November 2022 – Topic Last Reviewed: 26 November 2022

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