Hormone Therapy and Aging

“The benefits of hormone therapy outweigh the risks
for most healthy symptomatic women who are
aged younger than 60 years and within 10 years of…”.1

Umbrella
What may the Hormone Therapy and Aging Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT) and Aging/Prevention/Protection
  • Hormone Therapy (HT) and Aging/Prevention/Protection
  • Menopausal Hormone Therapy (MHT) and Aging/Prevention/Protection

Benefits and Risks

What are the benefit and risks of hormone therapy (HT) associated with aging?

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement published 07 July June 2022, the North American Menopause Society (NAMS) explain:

  • “The benefits of hormone therapy outweigh the risks for most healthy symptomatic women who are aged younger than 60 years and within 10 years of menopause onset”.2

Disease Prevention

Is HT recommended for disease prevention?

On page four in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

“HRT should not be recommended for the primary or secondary prevention of chronic disease in women experiencing the menopause in keeping with national and international guidelines”.3

2022 USPSTF Recommendations

What were the United States Preventative Services Task Force (USPSTF) recommendations about HT for the primary prevention of chronic conditions, published 01 November 2022?

Hormone Therapy and AgingIn Hormone Therapy In Postmenopausal Persons: Primary Prevention of Chronic Conditions – Recommendation Summary, the USPSTF recommend:

“Postmenopausal persons
The USPSTF recommends against the use of combined estrogen and progestin for the primary prevention of chronic conditions in postmenopausal persons”.4

Hormone Therapy and AgingIn Hormone Therapy In Postmenopausal Persons: Primary Prevention of Chronic Conditions – Recommendation Summary, the USPSTF recommended:

“Postmenopausal persons who have had a hysterectomy
The USPSTF recommends against the use of estrogen alone for the primary prevention of chronic conditions in postmenopausal persons who have had a hysterectomy”.5

Heart Disease

How may heart disease be prevented?

In Menopause FAQs: Your Health After Menopause – Q. Do I have to start worrying about heart disease? the NAMS elaborate on:

“A. You do. Although many women think of heart disease as a man’s disease, the number one killer of women in North America is cardiovascular disease, that is, diseases of the heart and circulatory system. After age 55, more than half of all the deaths in women are caused by cardiovascular disease. Risk for this disease increases after menopause. Be sure to talk to your healthcare team about what your risks are and how you can reduce them”.6

Bone Loss and Fractures

Does HT prevent bone loss and fractures in postmenopausal women?

In The 2023 Practitioner’s Toolkit for Managing Menopause: Management – Considerations for All Women At Menopause: Menopausal Hormone Therapy, published online 30 October 2023, the authors include:

  • “MHT prevents bone loss and fractures in postmenopausal women”.7

Stop or Not

If I am an older than 60 years, do I need to discontinue HT?

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement the NAMS note:

Hormone Therapy and Aging

  • “Hormone therapy does not need to be routinely discontinued in women aged older than 60 or 65 years and can be considered for continuation beyond age 65 for persistent VMS, quality-of-life issues, or prevention of osteoporosis after appropriate evaluation and counseling of benefits and risks”.8

Health Care Provider

What if I would like to choose to use HT?

If you choose to use HT, it may be in your best interest to also choose to talk to your health care provider about this.

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use. Discussions with women should also cover aspects such as when to consider stopping HRT and how this can be done (by gradually reducing the dose of HRT). No arbitrary limits should be set on age or duration of HRT intake”.9

Health Topics A-Z

Where may I find Health Topics A-Z related to Hormone Therapy and Aging?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

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New or Updated

  1. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  2. BMS Statement on Testosterone
  3. BMS TV: Bioidentical Hormones
  4. BMS TV: Coronary Heart Disease (CHD)
  5. BMS TV: HRT and Breast Cancer: Overall Risks and Benefits
  6. BMS TV: HRT and the Risk of Breast Cancer
  7. BMS TV: Hormone Replacement Therapy (HRT)
  8. BMS TV: Osteoporosis
  9. BMS TV: Testosterone Explained
  10. BMS TV: Urogenital Atrophy Explained
  11. Bioidentical Hormone Therapy
  12. Bioidentical Hormones: Are They Safer?
  13. Deciding About Hormone Therapy
  14. Deciding About Hormone Therapy Use
  15. Dr Louise Newson: The Truth About the Menopause & HRT
  16. FAQs: Hormone Therapy for Menopause
  17. Find A Menopause Practitioner [United States and Other]
  18. Find An AMS Doctor [Australasian Menopause Society i.e. Australia and New Zealand]
  19. Find Your Nearest BMS Menopause Specialist [British Menopause Society]
  20. Guidance on Menopausal Hormone Therapy
  21. HRT
  22. HRT & Menopause Extra
  23. HRT – Types, Doses and Regimens
  24. HRT: Benefits and Risks
  25. Healthy Living By Age
  26. Hormone Replacement Therapy (HRT) With Dr Nicky Peel & Prof. David Armstrong
  27. Hormone Replacement Therapy (HRT): Benefits and Risks of Hormone Replacement Therapy (HRT)
  28. Hormone Replacement Therapy (HRT): Types of Hormone Replacement Therapy (HRT)
  29. Hormone Replacement Therapy (HRT): Vaginal Oestrogen
  30. Hormone Therapy In Postmenopausal Persons: Primary Prevention of Chronic Conditions
  31. Hormone Therapy: Is It Right for You?
  32. Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
  33. I Forgot To Ask the Doctor – E9: The Menopause. Can Every Woman That Wants It Have HRT?
  34. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health [Other Languages and Formats]
  35. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?] [Other Languages and Formats]
  36. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Signs and Symptoms of Menopause [+ Video: Talking Menopause With Your GP] [Other Languages and Formats]
  37. Life’s Essential 8
  38. Maintaining Health and Preventing Disease After the Menopause
  39. May Is Osteoporosis Awareness and Prevention Month
  40. Mayo Clinic Minute: Combating Weight Gain During Menopause [+ Video Courtesy: Mayo Clinic News Network]
  41. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video]
  42. Mayo Clinic Minute: How Lifestyle Changes May Help Manage Menopause Symptoms [+ Video]
  43. Mayo Clinic Minute: Menopause and the Heart Connection [+ Video Courtesy: Mayo Clinic News Network]
  44. Mayo Clinic Q&A Podcast: Don’t Miss A Beat With Preventive Heart Care
  45. Mayo Clinic Q&A Podcast: Tips for Living Younger, Longer By Preventing Disease [+ Video Courtesy: Mayo Clinic News Network]
  46. Menopausal Hormone Therapy
  47. Menopause
  48. Menopause
  49. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  50. Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
  51. Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
  52. Menopause Patient Information [Videos] 4. The Different Types of HRT
  53. Menopause Patient Information [Videos] 5. Lifestyle Advice In Menopause & Perimenopause
  54. Menopause Preparedness Toolkit Video Series: Common Conditions Associated With Menopause and Midlife
  55. Menopause Preparedness Toolkit Video Series: Treating Vasomotor Symptoms of Menopause
  56. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
  57. Menopause Treatments: What Works, What Doesn’t
  58. Menopause and HRT
  59. Menopause, Perimenopause, Hormone Therapy and Other Treatments With Madelyn Butler, MD [Podcast]
  60. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  61. Menopause: Understanding the Changes and Finding Relief | Dr Susan Davis | The Proof Podcast EP 256
  62. National Center for Complementary and Integrative Health: Herbs At A Glance
  63. National Center for Complementary and Integrative Health: How Safe Is This Product or Practice?
  64. National Center for Complementary and Integrative Health: Women’s Health and Complementary Approaches
  65. Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
  66. Navigating Menopause: Honest Answers To All Your Questions [+ Video: What To Expect in Menopause]
  67. Non-Estrogen Treatments for Menopausal Symptoms
  68. Nonhormone Treatments for Hot Flashes and Night Sweats
  69. Perimenopause and Menopause Symptom Checklist
  70. Postmenopause
  71. Risks and Benefits of MHT
  72. Seven Facts To Know About Women’s Health
  73. Successful Aging: Tips for Keeping Your Body and Mind Sharp
  74. The 2023 Practitioner’s Toolkit for Managing Menopause
  75. Tips To Help Manage Menopause Symptoms
  76. The Truth About Menopause Supplements | Dr Sarah Berry
  77. Using Natural Therapies In the Menopause Transition – Webinar
  78. Vaginal Dryness
  79. Vaginal Dryness After Menopause: How To Treat It?
  80. Vaginal Dryness: What To Do About It
  81. Vaginal Oestrogen
  82. Video & Podcast Library: Interviews – Video: Genitourinary Syndrome of Menopause
  83. Video & Podcast Library: Interviews – Videos: Testosterone and Women
  84. Video Series-2023: New FDA-Approved Nonhormone Option for the Treatment of Hot Flashes
  85. Video Series-2023: Premature and Early Menopause
  86. Video Series-2024: Preparing for Your Menopause Health Care Visit
  87. Videos and Podcasts: Videos – Interviews: Heart Disease, Risk Factors of Developing Heart Disease, and Can I Take Hormones?
  88. Videos & Podcasts: Videos – Interviews: Preventing Bone Loss At Menopause
  89. Videos and Podcasts: Videos – Interviews: Prevention of Chronic Diseases In Women: Where Does MHT Fit In?
  90. Webinars: Previous – Approach To Bone Health In the Perimenopause and Postmenopause?
  91. Webinars: Previous – Hormones and Stroke: An Update on Treatment and Risk
  92. Webinars: Previous – Non-Hormonal Pharmacological Interventions For VMS
  93. Webinars: Previous – Non-Pharmacological Interventions For VMS
  94. What Everyone Should Know About Menopause Symptoms
  95. What Is Menopause? [+ Video]
  96. Why Didn’t Anyone Tell Me This? Episode 3: Dr Annice Mukherjee: Your Essential Menopause Toolkit
  97. World Menopause Day

Sources

Where may I find the Sources quoted?

You may find the Sources at:

Sources

  1. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 29 April 2024
  2. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:4. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 29 April 2024
  3. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 29 April 2024
  4. Hormone Therapy In Postmenopausal Persons: Primary Prevention of Chronic Conditions – Clinician Summary: To Whom Does This Recommendation Apply. 01 November 2022. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/menopausal-hormone-therapy-preventive-medication Accessed: 29 April 2024
  5. Hormone Therapy In Postmenopausal Persons: Primary Prevention of Chronic Conditions – Clinician Summary: To Whom Does This Recommendation Apply. 01 November 2022. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf/recommendation/menopausal-hormone-therapy-preventive-medication Accessed: 29 April 2024
  6. Davis, S. R., Taylor, S., Hemachandra, C., Magraith, K., Ebeling, P. R., Jane, F., and Islam, R. M. The 2023 Practitioner’s Toolkit for Managing Menopause: Management – Considerations for All Women At Menopause: Menopausal Hormone Therapy. First Published Online: 30 October 2023 https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783 Accessed: 29 April 2024
  7. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 29 April 2024
  8. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Optimising the Menopause Transition: Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2 https://journals.sagepub.com/doi/10.1177/20533691221104882 Accessed: 29 April 2024
Topic Last Updated: 29 April 2024 – Topic Last Reviewed: 29 April 2024

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