Hormone Therapy and Osteoporosis

“…HRT has been shown to have an effective role
in the prevention and treatment of osteoporosis.
Bisphosphonates are considered as first-line options…”.1

Umbrella
What may the Hormone Therapy and Osteoporosis Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Osteoporosis
  • Postmenopause Osteoporosis
  • Thin Bones

Bone Loss Prevention

Is hormone therapy (HT) approved for prevention of bone loss?

On page 775 in The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points, published July 2022 and “endorsed by more than 20 well-respected international organizations”, the North American Menopause Society (NAMS) note:

  • “Hormone therapy is FDA approved for prevention of bone loss, but not for treatment of osteoporosis. (Level I)”.2

What is FDA?

FDA can be an abbreviation for the (United States) Food and Drug Administration.

What is Level I?

In this context “Level I: Based on good and consistent scientific evidence”.

Early Menopause

What is one of the highlights about early menopause included in the 2022 Hormone Therapy Position Statement of the North American Menopause Society?

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement, published 07 July 2022, one of the highlights is:

  • “Women with primary ovarian insufficiency and premature or early menopause have higher risks of bone loss, heart disease, and cognitive or affective disorders associated with estrogen deficiency. It is recommended that hormone therapy can be used until at least the mean age of menopause unless there is a contraindication to its use”.3

Early Menopause and Breast Cancer Risk

What is one of the recommendations included in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause?

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “Women with POI and early menopause (40–45 years old) should be advised that HRT is unlikely to increase risk of breast cancer in younger menopausal women under the age of 50”.4

Postmenopausal Bone Loss

Does HT prevent bone loss in healthy postmenopausal women?

On page 775 in The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points the NAMS include:

  • “Hormone therapy prevents bone loss in healthy postmenopausal women, with dose-related effects on bone density. (Level I)”.5

Postmenopausal Fracture Risk

Does HT reduce fracture risk in healthy postmenopausal women?

On page 775 in The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points the NAMS include:

  • “Hormone therapy reduces fracture risk in healthy postmenopausal women. (Level I)”.6

Postmenopausal Osteoporosis

Can HT be used in the prevention of osteoporosis?

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

Hormone Therapy and Osteoporosis

  • “Bisphosphonates are considered as first-line options for most patients with postmenopausal osteoporosis due to their broad spectrum of anti-fracture efficacy”.7

Bisphosphonates

What are bisphosphonates?

DotS the definition of bisphosphonates may vary. In Bisphosphonates: What Are Biphosphenates? Drugs.com elaborate on:

“Bisphosphonates are a group of medicines that slow down or prevent bone loss, strengthening bones. Bisphosphonates inhibit osteoclasts which are responsible for breaking down and reabsorbing minerals such as calcium from bone (the process is known as bone resorption). Bisphosphonates allow osteoblasts (bone building cells) to work more effectively, improving bone mass”.8

Health Care Provider

What if I choose to use HT?

If you choose to use HT it may be in your best interest to also choose to talk to your health care provider about this.

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use”.9

Health Topics A-Z

Where may I find Health Topics A-Z related to Hormone Therapy and Osteoporosis?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy and Osteoporosis?

Your Country may have Links similar to:

Links

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New or Updated

  1. Ask Early Menopause.org
  2. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  3. BMS TV: Bioidentical Hormones
  4. BMS TV: Hormone Replacement Therapy (HRT)
  5. BonesBMS TV: Osteoporosis
  6. Bioidentical Hormones
  7. Bisphosphonates
  8. Bones and Beyond: The Benefits of Self-Care for Both Body and Mind
  9. Build Better Bones.org [International Osteoporosis Foundation]
  10. Compounded Bioidentical Hormone Therapy [Video]
  11. Deciding About Hormone Therapy
  12. Deciding About Hormone Therapy Use
  13. Dr Louise Newson: The Truth About the Menopause & HRT
  14. HRT
  15. HRT & Menopause Extra
  16. HRT and Alternatives
  17. HRT – Types, Doses and Regimens
  18. HRT: Benefits and Risks
  19. Health After Menopause
  20. Hormone Replacement Therapy (HRT)
  21. Hormone Replacement Therapy (HRT) With Dr Nicky Peel & Prof. David Armstrong
  22. Hormone Replacement Therapy (HRT): Types of Hormone Replacement Therapy (HRT)
  23. Hormone Therapy In Postmenopausal Persons: Primary Prevention of Chronic Conditions
  24. Hormone Therapy: Is It Right for You?
  25. I Forgot To Ask the Doctor – E9: The Menopause. Can Every Woman That Wants It Have HRT?
  26. Index To Drug-Specific Information [United States]
  27. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  28. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health
  29. Maintaining Health and Preventing Disease After the Menopause
  30. Making Choices At Menopause
  31. Managing Menopause: Don’t Let Symptoms of Menopause Reduce Your Quality of Life
  32. May Is Osteoporosis Awareness and Prevention Month [United States]
  33. Menopausal Hormone Therapy
  34. Menopausal Hormone Therapy and Breast Cancer Risk
  35. Menopause
  36. Menopause
  37. Menopause
  38. Menopause
  39. Menopause & Herbs
  40. Menopause Management Options: Menopausal Hormone Therapy (MHT)
  41. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  42. Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
  43. Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
  44. Menopause Patient Information [Videos] 4. The Different Types of HRT
  45. Menopause Patient Information [Videos] 5. Lifestyle Advice In Menopause & Perimenopause
  46. Menopause Preparedness Toolkit Video Series: Common Conditions Associated With Menopause and Midlife
  47. Menopause Preparedness Toolkit Video Series: Lifestyle Tips for Menopause
  48. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
  49. Menopause Treatments: What Works, What Doesn’t
  50. Menopause: Diagnosis & Treatment
  51. Menopause: Diagnosis and Management – Information for the Public: Benefits and Risks of HRT [NICE Guideline]
  52. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  53. Menopause: Ensuring A Tranquil Transition
  54. Menopause: Symptoms & Causes
  55. Menopause: Things You Can Do
  56. Menopause: Understanding the Changes and Finding Relief | Dr Susan Davis | The Proof Podcast EP 256
  57. Mymenoplan.org [My Menoplan, United States]
  58. National Center for Complementary and Integrative Health: Herbs At A Glance
  59. National Center for Complementary and Integrative Health: Natural Doesn’t Necessarily Mean Safer, or Better
  60. National Osteoporosis Month [May, United States]
  61. Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
  62. Osteoporosis
  63. Osteoporosis
  64. Osteoporosis
  65. Osteoporosis Treatment: A-Z of Osteoporosis Treatments
  66. Osteoporosis Treatment: Medications Can Help
  67. Osteoporosis: Bone Health Following Menopause
  68. Pathtogoodbonehealth.org [Your Path To Good Bone Health, Bone Health & Osteoporosis Foundation, United States]
    Osteoporosis
  69. Postmenopause
  70. Recipes: Bone Healthy Recipes [United States National Osteoporosis Foundation]
  71. Risks and Benefits of MHT
  72. Screening for Osteoporosis
  73. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement
  74. Therapy for the Effects of Menopause
  75. Tips To Help Manage Menopause Symptoms
  76. Treatment
  77. Treatment
  78. Updates on Exercise and Lifestyle Tips for Bone Strength With Joanne Fagerstrom, PT CFP
  79. Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
  80. Video Series-2023
  81. Videos and Podcasts: Videos – Interviews: Bone Health
  82. Videos and Podcasts: Videos – Interviews: Bone Health What Why and How
  83. Videos and Podcasts: Videos – Interviews: Prevention of Chronic Diseases In Women: Where Does MHT Fit In?
  84. Videos and Podcasts: Videos – Interviews: The Women’s Health Initiative – What Can We Believe?
  85. Webinars: Previous – Osteoporosis for Midlife Women and Beyond
  86. Webinars: Previous – Update on Bone Health
  87. What Are the Benefits and Risks of HRT?
  88. Why Didn’t Anyone Tell Me This? Episode 3: Dr Annice Mukherjee: Your Essential Menopause Toolkit
  89. What Is A Bone Density Test (DXA Scan)
  90. World Menopause Day 2021: Bone Health
  91. Worldosteoporosisday.org [World Osteoporosis Day]

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 22 August 2023
  2. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points. July 2022: 775. North American Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 22 August 2023
  3. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 22 August 2023
  4. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 22 August 2023
  5. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points. July 2022: 775. North American Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 22 August 2023
  6. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points. July 2022: 775. North American Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 22 August 2023
  7. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 22 August 2023
  8. Bisphosphonates: What Are Bisphosphonates? Drugs.com https://www.drugs.com/drug-class/bisphosphonates.html Accessed: 22 August 2023
  9. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 22 August 2023
Topic Last Updated: 22 August 2023 – Topic Last Reviewed: 22 August 2023

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