Hormone Therapy and Osteoporosis

“…HRT has been shown to have an effective role
in the prevention and treatment of osteoporosis.
Bisphosphonates are considered as first-line options…”.1

Umbrella
What may the Hormone Therapy and Osteoporosis Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Osteoporosis
  • Postmenopause Osteoporosis
  • Thin Bones

Bone Loss Prevention

Is hormone therapy (HT) approved for prevention of bone loss?

On page 775 in The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points, published July 2022 and “endorsed by more than 20 well-respected international organizations”, the North American Menopause Society (NAMS) note:

  • “Hormone therapy is FDA approved for prevention of bone loss, but not for treatment of osteoporosis. (Level I)”.2

What is FDA?

FDA can be an abbreviation for the (United States) Food and Drug Administration.

What is Level I?

In this context “Level I: Based on good and consistent scientific evidence”.

Early Menopause

What is one of the highlights about early menopause included in the 2022 Hormone Therapy Position Statement of the North American Menopause Society?

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement, published 07 July 2022, one of the highlights is:

  • “Women with primary ovarian insufficiency and premature or early menopause have higher risks of bone loss, heart disease, and cognitive or affective disorders associated with estrogen deficiency. It is recommended that hormone therapy can be used until at least the mean age of menopause unless there is a contraindication to its use”.3

Early Menopause and Breast Cancer Risk

What is one of the recommendations included in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause?

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published 10 June 2022, one of the recommendations is:

  • “Women with POI and early menopause (40–45 years old) should be advised that HRT is unlikely to increase risk of breast cancer in younger menopausal women under the age of 50”.4

Postmenopausal Bone Loss

Does HT prevent bone loss in healthy postmenopausal women?

On page 775 in The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points the NAMS include:

  • “Hormone therapy prevents bone loss in healthy postmenopausal women, with dose-related effects on bone density. (Level I)”.5

Postmenopausal Fracture Risk

Does HT reduce fracture risk in healthy postmenopausal women?

On page 775 in The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points the NAMS include:

  • “Hormone therapy reduces fracture risk in healthy postmenopausal women. (Level I)”.6

Postmenopausal Osteoporosis

Can HT be used in the prevention of osteoporosis?

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published 10 June 2022, one of the recommendations is:

Hormone Therapy and Osteoporosis

  • “Bisphosphonates are considered as first-line options for most patients with postmenopausal osteoporosis due to their broad spectrum of anti-fracture efficacy”.7

Bisphosphonates

What are bisphosphonates?

DotS the definition of bisphosphonates may vary. In Bisphosphonates: What Are Biphosphenates? Drugs.com elaborate on:

“Bisphosphonates are a group of medicines that slow down or prevent bone loss, strengthening bones. Bisphosphonates inhibit osteoclasts which are responsible for breaking down and reabsorbing minerals such as calcium from bone (the process is known as bone resorption). Bisphosphonates allow osteoblasts (bone building cells) to work more effectively, improving bone mass”.8

Health Care Provider

What if I choose to use HT?

If you choose to use HT it may be in your best interest to also choose to talk to your health care provider about this.

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published 10 June 2022, one of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use”.9

Health Topics A-Z

Where may I find Health Topics related to Hormone Therapy and Osteoporosis?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

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Links

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  1. 9 Myths and Misunderstandings About Menopausal Hormone Therapy (MHT)
  2. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  3. Bioidentical Hormones
  4. Bioidentical Hormones Explained – A British Menopause Society Video
  5. Bisphosphonates
  6. Combined Menopausal Hormone Therapy (MHT)
  7. Complementary Medicine Options for Menopausal Symptoms
  8. Complementary and Alternative Therapies Explained – A British Menopause Society Video
  9. Compounded Bioidentical Hormone Therapy [Video]
  10. Deciding About Hormone Therapy
  11. Deciding About Hormone Therapy Use
  12. EMAS Menopause Essentials
  13. EMAS Replay: Risk Assessment for MHT – When, To Whom, Which, and How Long? [Multiply Languages]
  14. HRT and Alternatives
  15. HRT: Types, Doses and Regimens
  16. Health After Menopause
  17. Hormone Replacement Therapy (HRT)
  18. Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
  19. Hormone Replacement Therapy (HRT): Alternatives
  20. Hormone Replacement Therapy (HRT): Types
  21. Hormone Therapy In Postmenopausal Women: Primary Prevention of Chronic Conditions
  22. Hormone Therapy: Is It Right for You?
  23. Index To Drug-Specific Information [United States]
  24. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  25. Lifestyle and Behaviour Changes for Menopausal Symptoms
  26. Lifestyle and Behavioural Modifications for Menopausal Symptoms
  27. Maintaining Health and Preventing Disease After the Menopause
  28. Making Choices At Menopause
  29. Making Sense of Menopausal Hormone Therapy Means Understanding the Benefits As Well As the Risks
  30. Managing Menopause: Don’t Let Symptoms of Menopause Reduce Your Quality of Life
  31. Menopausal Hormone Therapy
  32. Menopause
  33. Menopause
  34. Menopause
  35. Menopause & Herbs
  36. Menopause FAQs: Hormone Therapy for Menopause Symptoms
  37. Menopause FAQs: Your Health After Menopause
  38. Menopause Management: Hormone Replacement Therapy (HRT)
  39. Menopause Matters
  40. Menopause: Diagnosis & Treatment
  41. Menopause: Diagnosis and Management – Information for the Public: Benefits and Risks of HRT [NICE Guideline]
  42. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  43. Menopause: Is Menopausal Hormone Therapy (HRT) Safe? [Multiply Languages] [Video]
  44. Menopause: Medicines To Help You
  45. Menopause: Menopause – Hormone Treatments
  46. Menopause: Symptoms & Causes
  47. National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
  48. National Center for Complementary and Integrative Health: Natural Doesn’t Necessarily Mean Safer, or Better
  49. National Osteoporosis Month [May, United States]
  50. Non-Estrogen Treatments for Menopausal Symptoms
  51. Non-Hormonal Treatment Options for Menopausal Symptoms
  52. NonHormonal Treatments for Menopausal Symptoms
  53. Oestrogen Only Menopausal Hormone Therapy
  54. Osteoporosis
  55. Osteoporosis
  56. Osteoporosis
  57. Osteoporosis Explained – A British Menopause Society Video
  58. Osteoporosis Treatment: A-Z of Osteoporosis Treatments
  59. Osteoporosis Treatment: Medications Can Help
  60. Osteoporosis: Bone Health Following Menopause
  61. Recipes: Bone Healthy Recipes [United States National Osteoporosis Foundation]
  62. Risks and Benefits of MHT
  63. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement
  64. Treatment
  65. Treatment
  66. Treatment: Questions Patients Have About Medications [Video]
  67. Video Series-2021 – What Women Need To Know About Hormone Therapies
  68. Videos and Podcasts: Interviews and Podcasts – Interviews: Prevention of Chronic Diseases In Women: Where Does MHT Fit In?
  69. Videos and Podcasts: Interviews and Podcasts – Interviews: The Women’s Health Initiative – What Can We Believe?
  70. Videos and Podcasts: World Menopause Day 2021 – Interviews: Bone Health
  71. Videos and Podcasts: World Menopause Day 2021 – Interviews: Bone Health What Why and How
  72. Webinars: Previous – Osteoporosis for Midlife Women and Beyond
  73. Webinars: Previous – Update on Bone Health
  74. What Is Menopausal Hormone Therapy (MHT) and Is It Safe?
  75. World Menopause Day
    Hormone Therapy and Osteoporosis
  76. World Menopause Day: Patient Information Leaflet – Update on Bone Health [Multiply Languages]
    Hormone Therapy and Osteoporosis
  77. Worldosteoporosisday.org [World Osteoporosis Day]

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Hamoda et al. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 24 August 2022
  2. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points. July 2022: 775. North American Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 24 August 2022
  3. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 24 August 2022
  4. Hamoda et al. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 24 August 2022
  5. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points. July 2022: 775. North American Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 24 August 2022
  6. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Osteoporosis – Key Points. July 2022: 775. North American Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 24 August 2022
  7. Hamoda et al. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 24 August 2022
  8. Bisphosphonates: What Are Bisphosphonates? Drugs.com https://www.drugs.com/drug-class/bisphosphonates.html Accessed: 24 August 2022
  9. Hamoda et al. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 24 August 2022
Topic Last Updated: 24 August 2022 – Topic Last Reviewed: 24 August 2022

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