Hormone Therapy and Osteoporosis

Hormone Therapy and Osteoporosis

“MHT is first-line therapy for the prevention of menopause-
related bone loss. Benefits are most likely to outweigh any
risks when initiated within 10 years after menopause or…”.1

Umbrella

What may the Hormone Therapy and Osteoporosis Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Osteoporosis
  • Postmenopause Osteoporosis
  • Thin Bones

First-Line Therapy

Is menopause hormone therapy (MHT) a first-line therapy for the prevention of bone loss?

In International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause: 6. Osteoporosis, published 23 December 2026, the authors include:

  • “MHT is first-line therapy for the prevention of menopause-related bone loss. Benefits are most likely to outweigh any risks when initiated within 10 years after menopause or before age 60 years. Cessation of therapy leads to rapid bone loss. MHT significantly reduces the risk of osteoporosis-related fractures. ⨁⨁⨁◯ A”.2

Bisphosphonates

What are bisphosphonates?

DotS the definition of bisphosphonates may vary. In International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause: 6. Osteoporosis, the authors’ definition is:

  • “Bisphosphonates (BPs) are potent inhibitors of bone resorption with proven efficacy in the prevention of all osteoporosis-related fractures. It is indicated in women at high and very high risk of fracture… ⨁⨁⨁⨁ A”.3

Health Care Provider

What if I choose to use HT to prevent osteoporosis?

In International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause: 6. Osteoporosis the authors also note:

  • “All postmenopausal women should be educated on a bone-friendly lifestyle, including physical activity (resistance/weight-bearing exercise and falls prevention) and diet containing the recommended calcium intake and vitamin D. This is also an essential adjuvant to any pharmacological intervention. ⨁⨁⨁⨁ A”.4


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In Health Topics A-Z you may find:

Health Topics A-Z

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New or Updated

  1. Ask Early Menopause.org
  2. BMS TV: Osteoporosis
  3. Bioidentical Hormones
  4. Bisphosphonates
  5. Bone Health
  6. Bone Health & Osteoporosis Foundation [United States]
  7. Bone Health In Menopause
  8. Bone Health, Hormones and the Real Risk of Osteoporosis
  9. Bonetalk.org [Bone Talk, Bone Health & Osteoporosis Foundation, United States]
    Hormone Therapy and Osteoporosis
  10. Bones and Beyond: The Benefits of Self-Care for Both Body and Mind
  11. Bones, Joints and Ageing Well – Podcast
  12. Boosting Bone Density: Best Ways To Prevent Fractures As You Age [24 April 2026]
  13. Build Better Bones.org [International Osteoporosis Foundation]
    Hormone Therapy and Osteoporosis
  14. CAMS Menopause Hour: The Clinical Management and Risk of Postmenopausal Osteoporosis [Council of Affiliated Menopause Societies]
  15. Can Calcium Supplements Prevent Osteoporosis?
  16. Compounded Bioidentical Hormone Therapy [Video]
  17. Consumer Video and Podcast Series: 2024 Consumer Videos and Podcasts – Preparing for Your Menopause Health Care Visit
  18. Consumer Video and Podcast Series: 2025 Consumer Videos and Podcasts – Nutrition At Menopause and Why It Is Important
  19. Deciding About Hormone Therapy
  20. Deciding About Hormone Therapy Use
  21. HRT Questions Answered
  22. HRT – Types, Doses and Regimens
  23. HRT: How Can It Treat Osteoporosis
  24. Hormone Replacement Therapy (HRT)
  25. Hormone Replacement Therapy (HRT)
  26. Hormone Replacement Therapy (HRT): A Summary
  27. Hormone Replacement Therapy (HRT): Benefits and Risks
  28. Hormone Therapy In Postmenopausal Persons: Primary Prevention of Chronic Conditions
  29. Hormone Therapy: Is It Right for You?
  30. Hormones & Osteoporosis: The Hidden Risk for Women In Menopause | Dr Louise Newson
  31. International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause
  32. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  33. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – After the Menopause [Other Languages and Formats]
  34. May Is Osteoporosis Awareness and Prevention Month!
    Hormone Therapy and Osteoporosis
  35. Menopausal Symptom Treatments
  36. Menopause
  37. Menopause
  38. Menopause
  39. Menopause and HRT [Breast Cancer Risk]
  40. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  41. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
  42. Menopause: Diagnosis & Treatment
  43. Menopause: Ensuring A Tranquil Transition
  44. Menopause: Identification and Management [NICE Guideline]
  45. Menopause: Identification and Management [NICE Guideline]
    Hormone Therapy and Osteoporosis
  46. Menopause: Things You Can Do
  47. Mymenoplan.org [My Menoplan, United States]
  48. Online Events [International Menopause Society]: Past Webinars – 2024: Approach To Bone Health In the Perimenopause and Postmenopause?
  49. Online Events [International Menopause Society]: Past Webinars – 2025: Changing the Paradigm for Earlier Osteoporosis Prevention
  50. Online Events [International Menopause Society]: Past Webinars – 2025: Lifestyle Medicine
  51. Online Events [International Menopause Society]: Past Webinars – 2026: New IMS Recommendations – Lifestyle, Diet, Exercise
  52. Online Events [International Menopause Society]: Past Webinars – 2026: New IMS Recommendations – Midlife Body Changes
  53. Osteoporosis
  54. Osteoporosis
  55. Osteoporosis & Oestrogen
  56. Osteoporosis Treatment: A-Z of Osteoporosis Treatments
  57. Osteoporosis Treatment: Medications Can Help
  58. Osteoporosis, the Silent Disease, Can Shorten Your Life − Here’s How To Prevent Fractures and Keep Bones Healthy
  59. Osteoporosis: Bone Health Following Menopause
  60. Pathtogoodbonehealth.org [Your Path To Good Bone Health, Bone Health & Osteoporosis Foundation, United States]
  61. Postmenopause
  62. Risks and Benefits of MHT
  63. Screening for Osteoporosis
  64. The Menopause Society Statement on Misinformation Surrounding Hormone Therapy
  65. The Risks of Not Taking HRT | Dr Louise Newson
  66. The Women’s Health Initiative Randomized Trials and Clinical Practice
  67. The Women’s Health Initiative Trials: Clinical Messages
  68. Top Menopause Questions Answered: Hormones, Bones, Sex & Sleep
  69. Treatment
  70. Treatment
  71. Videos & Podcasts: Videos – Menopause and Hormone Therapy: Current Perspectives and Controversies
  72. Videos & Podcasts: Videos – Preventing Bone Loss At Menopause
  73. What Are the Benefits and Risks of HRT? [Videos]
  74. What Is A Bone Density Test (DXA Scan)
  75. World Menopause Day 2024: Leaflet for Women – Menopause and Menopause Hormone Therapy [Multiply Languages]
  76. Worldosteoporosisday.org [World Osteoporosis Day]

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Panay, N., et.al. International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause: 6. Osteoporosis. 23 December 2025 https://www.tandfonline.com/doi/full/10.1080/13697137.2025.2585487#abstract Accessed: 01 July 2026
  2. Panay, N., et.al. International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause: 6. Osteoporosis. 23 December 2025 https://www.tandfonline.com/doi/full/10.1080/13697137.2025.2585487#abstract Accessed: 01 July 2026
  3. Panay, N., et.al. International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause: 6. Osteoporosis. 23 December 2025 https://www.tandfonline.com/doi/full/10.1080/13697137.2025.2585487#abstract Accessed: 01 July 2026
  4. Panay, N., et.al. International Menopause Society (IMS) Recommendations and Key Messages on Women’s Midlife Health and Menopause: 6. Osteoporosis. 23 December 2025 https://www.tandfonline.com/doi/full/10.1080/13697137.2025.2585487#abstract Accessed: 01 July 2026
Topic Last Updated: 21 July 2026 – Topic Last Reviewed: 01 July 2026

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