“Before menopause, women have a lower risk of heart
disease than men. But, as women age and their
oestrogen levels fall, their risk of heart disease increases”.1

Umbrella

What may the Heart Disease and Menopause Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • After Menopause
  • Before Menopause
  • Cardiovascular Disease (CVD
  • Coronary Artery Disease (CAD)
  • Coronary Heart Disease (CHD)
  • Heart Conditions
  • Heart Disease/s
  • Perimenopause
  • Postmenopause

Heart Disease

What is heart disease?

DotS the definition of heart disease may vary. The (United States) Centers for Disease Control and Prevention’s definition is:

“The term “heart disease” refers to several types of heart conditions. The most common type of heart disease in the United States is coronary artery disease (CAD). CAD affects the blood flow to the heart. Decreased blood flow can cause a heart attack”.2

Early Menopause

Is there an association between early menopause and heart disease?

Yes. According to the (United States) National Institute of Heart, Lung, and Blood Institute (NHLBI):

Heart Disease and Menopause“Women who experience early menopause, especially after surgical removal of the uterus, are more likely to develop heart disease than women of the same age who have not yet experienced menopause”.3

Menopause

Heart Disease and MenopauseHeart Disease and MenopauseIs there an association between menopause and heart disease?

In What Is Menopause: Perimenopause, Menopause and Postmenopause – Postmenopause: Heart Health the (Australian) Jean Hailes for Women’s Health (JH) explain:

“Before menopause, women have a lower risk of heart disease than men. However, as women age and their oestrogen levels fall, their risk of cardiovascular disease increases. Heart disease is one of the leading cause of death for Australian women. Heart disease also claims three times as many lives as breast cancer”.4

In Menopause and Your Heart: Does Menopause Increase the Risk of Heart Disease? last updated 25 August 2025, the (Australian) Victor Chang Cardiac Research Institute note:

“Women tend to develop heart disease later in life than men – largely because they have been protected by the hormone oestrogen, which also plays a crucial role in reproduction.

But, during menopause, which most commonly happens to women aged between 45 and 55, the body starts to produce less of this hormone. Oestrogen helps to relax and dilate blood vessels, reduce inflammation, and improve cholesterol profiles.

The decrease in oestrogen levels, which occurs during menopause, can contribute to a higher risk of heart disease”.5

In Coronary Heart Disease: Women and Heart Disease – Why Does Coronary Heart Disease Affect Women Differently? the NHLBI elaborate on:

  • “Hormone changes may affect a woman’s risk for coronary heart disease. Before menopause, the hormone estrogen provides women with some protection against heart disease. However, as women age, their risk for coronary heart disease increases”.6

Postmenopause

Is there an association between postmenopause and heart disease?

The JH explain:

“After menopause, you may be more likely to develop risk factors for heart disease, including:

  • High blood pressure
  • An increase in total cholesterol
  • An increase in LDL (‘bad’ cholesterol)
  • A decrease in HDL (‘good’ cholesterol)
  • An increase in blood fats, such as triglycerides”.7

Hormone Replacement Therapy

Can hormone replacement therapy (HRT) reduce the risk of developing coronary heart disease?

In Menopause and Your Heart: Can Hormone Replacement Therapy (HRT) Reduce the Risk of Developing Heart Disease? the Victor Chang Cardiac Research Institute note:

“Some studies have suggested that HRT may have a protective effect by reducing the risk of coronary artery disease and atherosclerosis. However, other studies have shown that HRT can increase the rates of breast cancer, stroke, and blood clots. Therefore, HRT is not typically prescribed for protective effects against heart disease, but rather, is reserved for women with severe or refractory peri-menopausal symptoms. Therefore, the decision to use HRT should be made after a thorough discussion with a healthcare provider, as it comes with its own risks and benefits”.8

HRT + Heart Disease

Is there an association between HRT, blood clots and a stroke?

In Menopause and Your Heart: Is HRT Safe To Take If I Have Heart Disease? the Victor Chang Cardiac Research Institute explain:

“The safety of HRT varies from person to person, depending on factors such as age, the type and duration of HRT, and the presence of other risk factors for heart disease, like smoking, obesity, or a family history of heart problems.

It’s essential to consult with your doctor, preferably a cardiologist, to discuss the potential risks and benefits of HRT in your situation”.9 

Heart Disease Prevention

What are the most effective ways to prevent heart disease?

In The Connection Between Menopause and Cardiovascular Disease Risks, published 20 February 2023, the author includes:

“Research suggests the most effective ways to prevent heart disease include not smoking, being physically active, eating a healthy diet, maintaining a healthy weight, getting enough sleep, and keeping cholesterol, blood pressure and blood glucose levels under control”.10

In Menopause and Your Heart: What Can You Do To Lessen Your Risk of Developing Heart Disease During Menopause? the Victor Chang Cardiac Research Institute elaborate on:

“It’s important for women going through menopause to take proactive steps to maintain and improve their heart health, including:

  • Regular exercise…
  • Following a heart-healthy diet
  • Monitoring cholesterol levels
  • Managing blood pressure
  • A healthy weight
  • Cease smoking
  • Cut back on alcohol
  • Try to get a good night’s sleep”.11

Health Care Provider

What if I think I have heart disease or I have a family history of heart disease?

If you think you have heart disease or you have a family history of heart disease, it may be in your best interest to choose to talk to your health care provider about this.

In Heart Disease: It’s Not Just for Men – How Do I Find Out If I Am Risk for Heart Disease? You and Your Doctor: A Heart Healthy Partnership the NHLBI also remind us:

“A crucial step in determining your risk is to see your doctor for a thorough checkup. Your doctor can be an important partner in helping you set and reach goals for heart health. But don’t wait for your doctor to mention heart disease or its risk factors. Many doctors don’t routinely bring up the subject with women patients. Here are some tips for establishing good, clear communication between you and your doctor:

  • Speak Up…
  • Keep Tabs on Treatment…
  • Be Open…
  • Keep It Simple…”.12

Health Topics A-Z

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In Health Topics A-Z you may find:

Links

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Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. What Is Perimenopause and Menopause? Perimenopause, Menopause and Postmenopause – Postmenopause: Heart Health After Menopause. Last Updated: 28 August 2025 | Last Reviewed: 22 April 2025. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/about-menopause Accessed: 29 September 2025
  2. Heart Disease: About Heart Disease. 15 May 2024. Centers for Disease Control and Prevention https://www.cdc.gov/heart-disease/about/ Accessed: 29 September 2025
  3. Coronary Heart Disease: Women and Heart Disease – Why Does Coronary Heart Disease Affect Women Differently? Last Updated: 27 December 2024. National Heart, Lung, and Blood Institute https://www.nhlbi.nih.gov/health/coronary-heart-disease/women#Why-does-coronary-heart-disease-affect-women-differently? Accessed: 29 September 2025
  4. What Is Perimenopause and Menopause? Perimenopause, Menopause and Postmenopause – Postmenopause: Heart Health After Menopause. Last Updated: 28 August 2025 | Last Reviewed: 22 April 2025. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/about-menopause Accessed: 29 September 2025
  5. Menopause and Your Heart: Does Menopause Increase the Risk of Heart Disease? Last Updated: 25 August 2025. Victor Chang Cardiac Research Institute https://www.victorchang.edu.au/heart-disease/menopause Accessed: 29 September 2025
  6. Coronary Heart Disease: Women and Heart Disease – Why Does Coronary Heart Disease Affect Women Differently? Last Updated: 27 December 2024. National Heart, Lung, and Blood Institute https://www.nhlbi.nih.gov/health/coronary-heart-disease/women#Why-does-coronary-heart-disease-affect-women-differently? Accessed: 29 September 2025
  7. What Is Perimenopause and Menopause? Perimenopause, Menopause and Postmenopause – Postmenopause: Heart Health After Menopause. Last Updated: 28 August 2025 | Last Reviewed: 22 April 2025. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/about-menopause Accessed: 29 September 2025
  8. Menopause and Your Heart: Can Hormone Replacement Therapy (HRT) Reduce the Risk of Developing Heart Disease? Last Updated: 25 August 2025. Victor Chang Cardiac Research Institute https://www.victorchang.edu.au/heart-disease/menopause Accessed: 29 September 2025
  9. Menopause and Your Heart: Is HRT Safe To Take If I Have Heart Disease? Last Updated: 25 August 2025. Victor Chang Cardiac Research Institute https://www.victorchang.edu.au/heart-disease/menopause Accessed: 29 September 2025
  10. Williamson, L. The Connection Between Menopause and Cardiovascular Disease Risks. 21 February 2023 https://www.heart.org/en/news/2023/02/20/the-connection-between-menopause-and-cardiovascular-disease-risks Accessed: 29 September 2025
  11. Menopause and Your Heart: What Can You Do To Lessen Your Risk of Developing Heart Disease During Menopause Last Updated: 25 August 2025. Victor Chang Cardiac Research Institute https://www.victorchang.edu.au/heart-disease/menopause Accessed: 29 September 2025
  12. Heart Disease: It’s Not Just for Men – How Do I Find Out If I Am Risk for Heart Disease? You and Your Doctor: A Heart Healthy Partnership. National Heart, Lung, and Blood Institute https://www.nhlbi.nih.gov/health-topics/education-and-awareness/heart-truth/heart-disease-not-just-men Accessed: 29 September 2025
Topic Last Updated: 29 September 2025 – Topic Last Reviewed: 29 September 2025