Is your sex drive of concern to you? The use of testosterone is explained in a new clinical practice guideline to address the unmet need in women whose libido is of concern to them.

Testosterone Therapy for Women

What was the conclusion of the Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder In Women published online 01 April 2021?

In International Society for the Study of Women’s Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder In Women the International Society for the Study of Women’s Sexual Health (ISSWSH) conclusion was:

Conclusion

Despite substantial evidence regarding safety, efficacy, and clinical use, access to testosterone therapy for the treatment of HSDD in women remains a significant unmet need”.

What are the strengths and limitations of testosterone therapy?

In International Society for the Study of Women’s Sexual Health Clinical Practice Guideline for the Use of Systemic Testosterone for Hypoactive Sexual Desire Disorder In Women the ISSWSH explain:

Testosterone Therapy for Women Update April 2021

Strengths & Limitations

This evidence-based guideline builds on a recently published comprehensive meta-analysis and the Global Position Statement endorsed by numerous societies. The limitation is that testosterone therapy is not approved for women by most regulatory agencies, thereby making prescribing and proper dosing challenging”.

Hypoactive Sexual Desire Disorder In Women

What is Hypoactive Sexual Desire Disorder (HSDD) in women?

In Low Sex Drive In Women the (United States) Mayo Clinic’s definition is:

“By definition, you may be diagnosed with hypoactive sexual desire disorder if you frequently lack sexual thoughts or desire, and the absence of these feelings causes personal distress. Whether you fit this medical diagnosis or not, your doctor can look for reasons that your sex drive isn’t as high as you’d like and find ways to help”.

Testosterone Therapy Global Consensus Position Statement

What was the conclusion of the first Global Consensus Position Statement on the Use of Testosterone Therapy for Women – endorsed by 11 organizations – published online 02 September 2019?

In International Consensus on Testosterone Treatment for Women the (Australian) Jean Hailes for Women’s Health (JH) explain the conclusion of the Global Consensus Position Statement on the Use of Testosterone Therapy for Women was:

Testosterone Therapy for Women Update April 2021

“They concluded that testosterone can be effective at improving sexual wellbeing for postmenopausal women with Hypoactive Sexual Desire Dysfunction (HSDD). Recognised benefits included improved sexual desire, arousal, orgasm and pleasure, together with reduced concerns and distress about sex”.

To Use or Not

What did the Abstract for the Australasian Menopause Society’s (AMS) webinar about the use of testosterone in women include?

In Webinar: What’s New – The Use of Testosterone In Women | 24 March 2021 the AMS Abstract included:

“Based on the available data, testosterone supplementation should not be used to improve cardiometabolic, musculoskeletal or cognitive health, wellbeing and low mood, or vasomotor symptoms in postmenopausal women; there are presently insufficient data to support the use of testosterone in premenopausal women. Globally, the use of compounded testosterone formulations is discouraged, and when these are the only treatment option, adherence to the highest manufacturing standard is required. In Australia, a TGA approved testosterone is now available. Therefore this abrogates the need to prescribe compounded testosterone. Testosterone supplementation for women with HSDD should always be considered a trial of therapy”.

Health Care Provider

What if I am considering testosterone therapy?

If you are considering testosterone therapy, it may be in your best interest to choose to talk to your health care provider about this.

In Menopause Management: Menopausal Hormone Therapy (MHT) – What Are the Risks of Testosterone Therapy? the (Australian) Jean Hailes for Women’s Health elaborate on:

“If you are considering testosterone therapy, talk to your doctor to gain a clear understanding of what is currently known about this therapy. It is essential for women undergoing testosterone treatment to be supervised by doctors who are experts in this area”.

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Last Updated: 07 April 2021 – Last Revised: 05 April 2021
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