Hormone Therapy and Blood Clots

“Transdermal routes of administration and lower doses
of hormone therapy may decrease risk
of venous thromboembolism and stroke”.1

Umbrella

What may the Hormone Therapy and Blood Clots Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Blood Clots
  • Deep Vein Thrombosis (DVT)
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Venous Thromboembolism (VTE)
  • Venous Thrombosis

Blood Clot Risk

What is the association between hormone therapy (HT) and blood clot risk?

On page four of Menopause and Menopause Hormone Therapy: 4. Why Is MHT Important? What Are the Risks? the International Menopause Society’s (IMS) Leaflet for Women for World Menopause Day 2024, the IMS elaborate on:Hormone Therapy and Blood Clots

“While MHT offers many benefits, there are some small risks:…

  • …Blood clots: This risk is higher with certain forms of MHT, like tablets”.2

Transdermal

What is the association between transdermal administration of estradial and blood clots?

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement, published 07 July 2022, the North American Menopause Society (NAMS) (now the Menopause Society) note:

“Transdermal routes of administration and lower doses of hormone therapy may decrease risk of venous thromboembolism and stroke”.3

On page three in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “Transdermal administration of estradiol is unlikely to increase the risk of venous thrombosis or stroke above that in non-users and is associated with a lower risk compared with oral administration of estradiol. The transdermal route should therefore be considered as the first choice route of estradiol administration in women with related risk factors”.4

Health Care Provider

If I choose to use HT, what is my risk of blood clots?

On page three of Menopause and Menopause Hormone Therapy: 1. Who Is MHT For? Women With Existing Medical Conditions the IMS explain:

“Women with certain medical histories such as breast cancer and blood clots should talk to their healthcare professional about whether MHT is safe for them. Deciding to use MHT is a personal choice and should involve discussions about the benefits and risks with a healthcare professional who knows your health history”.5

Health Topics A-Z

Where may I find Health Topics A-Z related to Hormone Therapy and Blood Clots?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy and Blood Clots?

Your Country may have Links similar to:

Links

This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.

New or Updated

  1. 6 Blood Clot Signs You Shouldn’t Ignore
  2. Askearlymenopause.org [Ask EM] [+ Video: What Is Early Menopause?]
  3. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  4. BMS TV: Bioidentical Hormones
  5. BMS TV: Coronary Heart Disease (CHD)
  6. BMS TV: Hormone Replacement Therapy (HRT)
  7. Bioidentical Custom Compounded Hormone Therapy
  8. Bioidentical Hormones: Are They Safer?
  9. Blood Clots
  10. Blood Clots
  11. Cognitive Behaviour Therapy (CBT) for Menopausal Symptoms
  12. Consumer Video and Podcast Series: 2023 Consumer Videos and Podcasts – NAMS 2023 Nonhormone Therapies Position Statement for Bothersome Menopause Symptoms
  13. Consumer Video and Podcast Series: 2023 Consumer Videos and Podcasts – New FDA-Approved Nonhormone Option for the Treatment of Hot Flashes
  14. Consumer Video and Podcast Series: 2024 Consumer Videos and Podcasts – Preparing for Your Menopause Healthcare Visit
  15. Deciding About Hormone Therapy
  16. Deciding About Hormone Therapy Use
  17. Deep Vein Thrombosis
  18. Deep Vein Thrombosis (DVT)
  19. FAQs: Hormone Therapy for Menopause
  20. FAQs: Preventing Deep Vein Thrombosis
  21. February Is American Heart Month
    Hormone Therapy and Blood Clots
  22. Guidance on Menopausal Hormone Therapy [Video]
  23. HRT
  24. HRT Questions Answered
  25. HRT – Types, Doses and Regimens
  26. HRT: Benefits and Risks
  27. Hormone Replacement Therapy (HRT): Benefits and Risks of Hormone Replacement Therapy (HRT) – Blood Clots
  28. Hormone Therapy
  29. Hormone Therapy: Is It Right for You?
  30. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  31. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video]
  32. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video] [+ Video Courtesy: Mayo Clinic News Network]
  33. Mayo Clinic Minute: How Lifestyle Changes May Help Manage Menopause Symptoms [+ Video]
  34. Mayo Clinic Minute: Menopause and the Heart Connection [+ Video Courtesy: Mayo Clinic News Network]
  35. Mayo Clinic Minute: Signs of Coronary Artery Disease, How To Reduce Your Risk [+ Video]
  36. Menopausal Hormone Therapy
  37. Menopausal Hormone Therapy and Breast Cancer Risk
  38. Menopausal Hormone Therapy and Venous Thromboembolism
  39. Menopausal Hormone Therapy, Heart Disease and Stroke
  40. Menopause
  41. Menopause
  42. Menopause
  43. Menopause: Identification and Management NICE Guideline Published: 12 November 2015 Last Updated: 07 November 2024]
    Hormone Therapy and Blood Clots
  44. Menopause and Natural Therapies
  45. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
    Hormone Therapy and Blood Clots
  46. Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
  47. Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
  48. Menopause Patient Information [Videos] 4. The Different Types of HRT
  49. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
  50. Menopause Treatments: What Works, What Doesn’t
  51. Menopause: Diagnosis & Treatment
  52. Menopause: Understanding the Changes and Finding Relief | Dr Susan Davis | The Proof Podcast EP 256
  53. National Center for Complementary and Integrative Health: Herbs At A Glance
  54. National Center for Complementary and Integrative Health: How Safe Is This Product or Practice?
  55. Natural Remedies To Help Manage Perimenopause Symptoms
  56. Natural Therapies
  57. Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
  58. Non-Estrogen Treatments for Menopausal Symptoms
  59. Nonhormone Treatments for Hot Flashes and Night Sweats
  60. Office of Dietary Supplements: Dietary Supplement Fact Sheets
  61. Revised Global Consensus Statement on Menopausal Hormone Therapy
  62. Risks and Benefits of MHT
  63. Statin Use and the Risk of Venous Thromboembolism In Women Taking Hormone Therapy
  64. The Basics of Blood Clots: What You Need To Know
  65. The Menopause Society Statement on Misinformation Surrounding Hormone Therapy [September 2024]
    Hormone Therapy and Blood Clots
  66. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement
  67. The Truth About Menopause Supplements | Dr Sarah Berry
  68. The Women’s Health Initiative Trials: Clinical Messages
  69. Types of Hormone Therapy
  70. Venous Thromboembolism (Blood Clots)
  71. Videos & Podcasts: Videos – Cardiovascular Disease In Women
  72. Videos & Podcasts: Videos – Menopause and Hormone Therapy: Current Perspectives and Controversies
  73. Videos and Podcasts: Videos – Interviews: Heart Disease, Risk Factors of Developing Heart Disease, and Can I Take Hormones?
  74. Webinars: Previous – Cardiovascular Disease
  75. Webinars: Previous – Recommendations on Cardiovascular Risk Assessment
  76. What To Avoid When Taking A Blood Thinner
  77. ‘What’s Normal Has Changed’: Navigating Menopausal Hormone Therapy As CVD Risk Grows
  78. World Menopause Day 2023
    Hormone Therapy and Blood Clots
  79. World Menopause Day 2023: Patient Information Leaflet
  80. Hormone Therapy and Blood Clots World Menopause Day 2024: Poster for Women

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://menopause.org/wp-content/uploads/press-release/ht-position-statement-release.pdf Accessed: 25 February 2025
  2. Menopause and Menopause Hormone Therapy: 4. Why Is MHT Important? What Are the Risks? 2024:7. International Menopause Society https://www.imsociety.org/wp-content/uploads/2024/10/2024-WMD-Leaflet_English.pdf Accessed: 25 February 2025
  3. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://menopause.org/wp-content/uploads/press-release/ht-position-statement-release.pdf Accessed: 25 February 2025
  4. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:3-4. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 25 February 2025
  5. Menopause and Menopause Hormone Therapy: 1. Who Is MHT For? Women With Existing Medical Conditions. 2024:3. International Menopause Society https://www.imsociety.org/wp-content/uploads/2024/10/2024-WMD-Leaflet_English.pdf Accessed: 25 February 2025
Topic Last Updated: 25 February 2025 – Topic Last Reviewed: 25 February 2025

Print Friendly, PDF & Email
/by