Hormone Therapy and Stroke

“ Hormone therapy might slightly increase
your risk of stroke or blood clots in the legs or lungs
(especially if taken in pill form)”.1

Umbrella
What may the Hormone Therapy and Stroke Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Cardiovascular Disease
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Stroke

Cardiovascular Disease

What is cardiovascular disease (CVD)?

DotS the definition of CVD may vary. In Cardiovascular Heart Disease the British Heart Foundation’s (BHF) definition is:

“Cardiovascular disease (CVD), also called heart and circulatory disease, is an umbrella name for conditions that affect your heart or circulation. These include high blood pressure, stroke and vascular dementia”.2

Stroke

What is a stroke?

DotS the definition of a stroke may vary. The American Stroke Association’s definition is:

“A stroke occurs when a blood vessel that carries oxygen and nutrients to the brain is either blocked by a clot or bursts (or ruptures). When that happens, part of the brain cannot get the blood (and oxygen) it needs, so it and brain cells die”.3

Primary Ovarian Insufficiency and Premature or Early Menopause

Is HT recommended for women with primary ovarian insufficiency and premature or early menopause?

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement, published 07 July 2022, the North American Menopause Society (NAMS) explain:

  • “Women with primary ovarian insufficiency and premature or early menopause have higher risks of bone loss, heart disease, and cognitive or affective disorders associated with estrogen deficiency. It is recommended that hormone therapy can be used until at least the mean age of menopause unless there is a contraindication to its use”.4

Risk

Are risks of stroke associated with HT?

On page one in Deciding About Hormone Therapy Use: Potential Benefits, published July 2022, the NAM explain:


Hormone Therapy and Stroke“As with all medications, HT is associated with some potential risks. For healthy women with bothersome hot flashes aged younger than 60 years or within 10 years of menopause, the benefits of HT generally outweigh the risks. Hormone therapy might slightly increase your risk of stroke or blood clots in the legs or lungs (especially if taken in pill form)”.5

In Menopausal Hormone Therapy, Heart Disease and Stroke the European Menopause and Andropause Society note:

  • “MHT may confer a small risk of stroke, more so with oral than with transdermal estrogen”.6

Chronic Disease

Is HT recommended for the prevention of stroke?

On page four in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “HRT should not be recommended for the primary or secondary prevention of chronic disease in women experiencing the menopause in keeping with national and international guidelines”.7

Health Care Provider

If I choose to use HT what is my risk of stroke?

Different women who choose to use HT can have different risks of stroke. It may therefore be in your best interest to also choose to talk to your health care provider about this.

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause another of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use”.8

Health Topics A-Z

Where may I find Health Topics related to Hormone Therapy and Stroke?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

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Links

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New or Updated

  1. 5 Critical Steps To Help Prevent A Stroke
  2. 7 Things You Can Do To Prevent A Stroke
  3. About Stroke
  4. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  5. Bioidentical Hormone Therapy
  6. Bioidentical Hormones Explained – A British Menopause Society Video
  7. Bioidentical Hormones: Are They Safer?
  8. Blood Clots
  9. Cardiovascular Diseases
  10. Combined Menopausal Hormone Therapy (MHT)
  11. Consumer Health: Menopause, Hormone Replacement Therapy and Heart Health
  12. Consumer Health: Stroke Awareness
  13. Deciding About Hormone Therapy
  14. Deciding About Hormone Therapy Use
  15. Dr Gail Busby – I Forgot To Ask the Doctor – Episode 9 The Menopause
  16. EMAS Menopause Essentials
  17. EMAS Replay [Webinars]
  18. Early Menopause: Women’s Experiences
  19. Estrogen & Hormones
  20. Estrogen, Hormone Therapy and Menopause
  21. Family History
  22. February Is American Heart Month
  23. Find A Menopause Practitioner [United States and Other]
  24. Find An AMS Doctor [Australasian Menopause Society i.e. Australia and New Zealand]
  25. Find Your Nearest BMS Menopause Specialist [British Menopause Society]
  26. HRT & Menopause Extra
  27. HRT – Types, Doses and Regimens
  28. HRT: Benefits and Risks
  29. HRT: Summary
  30. Healthy Lifestyle
  31. Hormone Replacement Therapy
  32. Hormone Replacement Therapy (HRT)
  33. Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
  34. Hormone Replacement Therapy (HRT): Alternatives
  35. Hormone Replacement Therapy (HRT): Risks
  36. Hormone Therapy: Is It Right for You?
  37. Hot Flashes
  38. Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
  39. Hypertension
  40. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?]
  41. Learning To Cope With Hot Flashes
  42. Let’s Talk About Perimenopause
  43. Lifestyle and Behavioural Modifications for Menopausal Symptoms
  44. Life’s Essential 8
  45. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause
  46. Mayo Clinic Minute: How Lifestyle Changes May Help Manage Menopause Symptoms [+ Video]
  47. Mayo Clinic Q and A: 21st Century Stroke Prevention Strategies
  48. Menopausal Hormone Therapy
  49. Menopausal Hormone Therapy, Heart Disease and Stroke
  50. Menopause
  51. Menopause
  52. Menopause Management: Hormone Replacement Therapy (HRT) – Cardiovascular Disease & HRT
  53. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  54. Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
  55. Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
  56. Menopause Patient Information [Videos] 4. The Different Types of HRT
  57. Menopause Patient Information [Videos] 5. Lifestyle Advice In Menopause & Perimenopause
  58. Menopause Preparedness Toolkit Video Series: Common Conditions Associated With Menopause and Midlife
  59. Menopause Preparedness Toolkit Video Series: Lifestyle Tips for Menopause Wellness
  60. Menopause Preparedness Toolkit: A Woman’s Empowerment Guide
  61. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
  62. Menopause Treatments: What Works, What Doesn’t
  63. Menopause and Heart Disease
  64. Menopause and Your Health
  65. Menopause: Diagnosis and Management – Information for the Public: Benefits and Risks of HRT – Heart Disease and Stroke (Cardiovascular Disease) [NICE Guideline]
  66. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  67. Menopause: Treatment
  68. National Center for Complementary and Integrative Health: Know the Science: How Medications and Supplements Can Interact
  69. National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
  70. Natural Remedies To Help Manage Perimenopause Symptoms
  71. Natural Therapies & Supplements
  72. Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
  73. Non-Estrogen Treatments for Menopausal Symptoms
  74. Oestrogen Only Menopausal Hormone Therapy
  75. Perimenopause
  76. Postmenopause
  77. Preventing Cardiovascular Disease
  78. Revised Global Consensus Statement on Menopausal Hormone Therapy
  79. Staying Healthy During and After Menopause
  80. Stroke
  81. Stroke
  82. Stroke
  83. Stroke
  84. Stroke.org [American Stroke Association]
  85. The Menopause: After the Menopause
  86. Tipos de Hormonoterapia
  87. Tips To Help Manage Menopause Symptoms
  88. Types of Hormone Therapy
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  90. Venous Thrombosis/Thromboembolism Risk and Menopausal Treatments
  91. Video Series-2021: How Clinicians Determine Which Women May Benefit From Statin Therapy
  92. Video Series-2021: What You Need to Know About the #1 Cause of Death in Women
  93. Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
  94. Videos and Podcasts: Videos – Interviews: Prevention of Chronic Diseases In Women: Where Does MHT Fit In?
  95. Webinars: Previous – Primary Prevention of Cardiovascular Disease With MHT – Where Are We Now?
  96. Webinars: Previous – The Heart of the Matter
  97. What Can I Do To Help With Hot Flashes?
  98. What Is Cardiovascular Disease?
  99. Why Didn’t Anyone Tell Me This? Episode 3: Dr Annice Mukherjee: Your Essential Menopause Toolkit
  100. World Stroke Day [29 October]
    Hormone Therapy and Stroke

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 20 February 2023
  2. Cardiovascular Heart Disease. Page Last Reviewed: October 2019. British Heart Foundation https://www.bhf.org.uk/informationsupport/conditions/cardiovascular-heart-disease Accessed: 20 February 2023
  3. About Stroke. American Stroke Association https://www.stroke.org/en/about-stroke Accessed: 20 February 2023
  4. Deciding About Hormone Therapy: Potential Risks. July 2022. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 20 February 2023
  5. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022. North American Menopause Society https://www.menopause.org/docs/default-source/press-release/ht-position-statement-release.pdf Accessed: 20 February 2023
  6. Menopausal Hormone Therapy, Heart Disease and Stroke. 2022. European Menopause and Andropause Society
    https://emas-online.org/wp-content/uploads/2022/05/Menopausal-hormone-therapy-heart-disease-and-stroke.pdf Accessed: 20 February 2023
  7. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:3-4. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 20 February 2023
  8. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 20 February 2023
Topic Last Updated: 20 February 2023 – Topic Last Reviewed: 20 February 2023

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