Hormone Therapy 2016 Revised Global Consensus Statement

“Hopefully, this statement will enable health-care providers to offer those women in midlife, who may benefit from MHT, the opportunity to make an informed decision”.1

Umbrella
What may the Hormone Therapy 2016 Revised Global Consensus Statement Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Revised Global Consensus Statement on Menopausal Hormone Therapy

Revised Global Consensus Statement

What is the Revised Global Consensus Statement on Menopausal Hormone Therapy?

Hormone Therapy 2016 Revised Global Consensus StatementIn the Revised Global Consensus Statement on Menopausal Hormone Therapy (Revised Global Consensus Statement) – endorsed by seven menopause-related organizations – published online 20 June 2016, the authors explain:

“The publication of the Global Consensus on Menopausal Hormone Therapy in 2013 by leading global menopause societies succeeded in presenting guidelines in a troubled therapeutic area that are helpful to both health-care providers and potential users of menopausal hormone therapy (MHT). The revised statement is aimed at updating and expanding the areas of consensus”.2

Organizations

Which organizations endorse the Revised Global Consensus Statement?

Organizations which endorse the Revised Global Consensus Statement (in alphabetical order) are the:

Organizations

  1. Asia Pacific Menopause Federation
  2. Endocrine Society
  3. European Menopause and Andropause Society
  4. Federation of Latin American Menopause Societies
  5. International Menopause Society
  6. International Osteoporosis Foundation
  7. North American Menopause Society

Hopeful

What are the Revised Global Consensus Statement authors hopeful of?

The Revised Global Consensus Statement authors note:

“Hopefully, this statement will enable health-care providers to offer those women in midlife, who may benefit from MHT, the opportunity to make an informed decision”.3

Acknowledgement

What do the Revised Global Consensus Statement authors acknowledge?

The Revised Global Consensus Statement authors acknowledge:

“The revised statement contains only areas of consensus and does not replace the more detailed and fully referenced recommendations of the individual societies (referenced at the end of the document)”.4

Consensus

What are some points of consensus in the Revised Global Consensus Statement?

Some points of consensus are:

  • “MHT, including tibolone and the combination of conjugated equine estrogens and bazedoxifene (CE/BZA), is the most effective treatment for vasomotor symptoms (VMS) associated with menopause at any age, but benefits are more likely to outweigh risks if initiated for symptomatic women before the age of 60 years or within 10 years after menopause
  • If MHT is contraindicated or not desired for treatment of VMS, selective serotonin reuptake inhibitors and serotoninnorepinephrine reuptake inhibitors such as paroxetine, escitalopram, venlafaxine and desvenlafaxine, which have been shown to be effective in randomized controlled trials (RCTs), may be considered. Gabapentin may also be considered
  • Local low-dose estrogen therapy is preferred for women whose symptoms are limited to vaginal dryness or associated discomfort with intercourse or for the prevention of recurrent urinary tract infections”.5

Vasomotor Symptoms

What are vasomotor symptoms?

DotS the definition of vasomotor symptoms may vary. The North American Menopause Society’s definition is:

“Vasomotor symptoms. Also known as hot flashes and night sweats, common symptoms during perimenopause and early postmenopause”.6

Health Care Provider

What if I choose to use MHT?

If you choose to use MHT, it may be in your best interest to also choose to talk to your health care provider about this.

One of the points of consensus in the Revised Global Consensus Statement is:

  • “The option of MHT is an individual decision in terms of quality of life and health priorities as well as personal risk factors such as age, time since menopause and the risk of VTE, stroke, ischemic heart disease and breast cancer. MHT should not be recommended without a clear indication for its use”.7

What is VTE?

MHT can be an abbreviation for Venous Thromboembolism.

Health Topics A-Z

Where may I find Health Topics related to Hormone Therapy 2016 Global Consensus Statement?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy 2016 Global Consensus Statement?

Your Country may have Links similar to:

Links

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  1. 2016 IMS Recommendations on Women’s Midlife Health and Menopause Hormone Therapy
  2. 9 Myths and Misunderstandings About Menopausal Hormone Therapy (MHT)
  3. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  4. Bioidentical Custom Compounded Hormone Therapy
  5. Bioidentical Hormone Therapy
  6. Bioidentical Hormones Explained – A British Menopause Society Video
  7. Bioidentical Hormones: Are They Safer?
  8. Combined Menopausal Hormone Therapy (MHT)
  9. Complementary Medicine Options for Menopausal Symptoms
  10. Complementary and Alternative Therapies Explained – A British Menopause Society Video
  11. Compounded Bioidentical Hormone Therapy [Video]
  12. Compounded Bioidentical Hormones In Endocrinology Practice: An Endocrine Society Scientific Statement
  13. Deciding About Hormone Therapy
  14. Deciding About Hormone Therapy Use
  15. Early Menopause: Experiences and Perspectives of Women and Health Practitioners – Women’s Profiles
  16. Estrogen & Hormones: Estrogen & Heart Disease
  17. Find A Menopause Practitioner [United States and Other]
  18. Find An AMS Doctor [Australasian Menopause Society i.e. Australia and New Zealand]
  19. Find Your Nearest BMS-Recognised Menopause Specialist [British Menopause Society]
  20. Global Consensus Statement on Menopausal Hormone Therapy
  21. HRT and Bleeding Explained – A British Menopause Society Video
  22. HRT and Breast Cancer: Overall Risks and Benefits Explained – A British Menopause Society Video
  23. HRT and the Risk of Breast Cancer Explained – A British Menopause Society Video
  24. HRT: Benefits and Risks
  25. HRT: The History
  26. Hormone Help Desk: ET, EPT, and More
  27. Hormone Replacement Therapy
  28. Hormone Replacement Therapy (HRT)
  29. Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
  30. Hormone Replacement Therapy (HRT): Risks of HRT
  31. Hormone Replacement Therapy (HRT): Types
  32. Hormone Therapy: Is It Right for You?
  33. Hormones After Age 65 Are OK for Some Women
  34. Hot Flashes: Manage Without Medication?
  35. Hot Flashes: What Can I Do?
  36. Information About Menopause [Multiply Languages] [Videos]
  37. Jean Hailes MHT Position Statement
  38. La Menopausia Y Las Hormonas: Preguntas Para Su Médico
  39. Lifestyle and Behaviour Changes for Menopausal Symptoms
  40. Lifestyle and Behavioural Modifications for Menopausal Symptoms
  41. MHT and Breast Cancer Risk
  42. Making Choices At Menopause
  43. Making Sense of Menopausal Hormone Therapy Means Understanding the Benefits As Well As the Risks
  44. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video Courtesy: Mayo Clinic News Network]
  45. Mayo Clinic Minute: Lifestyle Changes To Manage Menopause Symptoms [+ Video Courtesy: Mayo Clinic News Network]
  46. Mayo Clinic Q and A: Estrogen Replacement Therapy After Ovary Removal
  47. Menopausal Hormone Therapy Trends Before Versus After 2002: Impact of the Women’s Health Initiative Study Results
  48. Menopause
  49. Menopause
  50. Menopause
  51. Menopause & Hormones: Questions To Ask Your Doctor
  52. Menopause FAQs: Hormone Therapy for Menopause Symptoms
  53. Menopause Hormone Therapy and Your Heart
  54. Menopause Hormone Therapy: Follow-Up Appointments
  55. Menopause Hormone Therapy: Who Shouldn’t Take It?
  56. Menopause Matters
  57. Menopause Symptoms and Relief
  58. Menopause Treatment
  59. Menopause What Are the Symptoms?
  60. Menopause – Is Menopausal Hormone Therapy (HRT) Safe? [Multiply Languages] [Video]
  61. Menopause – What Is Menopausal Hormone Therapy (HRT)? [Multiply Languages] [Video]
  62. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  63. Menopause: Hormone Replacement Therapy (HRT) [Video Interview Stories]
  64. Menopause: Medicines To Help You
  65. Menopause: Menopause – Hormone Treatments
  66. Menopause: Non-HRT and Lifestyle Options [Video Interview Stories]
  67. Menopause: Non-Hormonal Treatment & Relief for Hot Flashes
  68. NAMS 2017 Position Statement Updates Guidelines for Hormone Therapy Use
  69. NAMS Supports Judicious Use of Systemic Hormone Therapy for Women Aged 65 Years and Older
  70. National Center for Complementary and Integrative Health: 4 Things To Know About Menopausal Symptoms and Complementary Health Practices
  71. National Center for Complementary and Integrative Health: Know the Science: How Medications and Supplements Can Interact
  72. National Center for Complementary and Integrative Health: Menopausal Symptoms In Depth
  73. Non-Hormonal Treatment Options for Menopausal Symptoms
  74. NonHormonal Treatments for Menopausal Symptoms
  75. Oestrogen Only Menopausal Hormone Therapy
  76. Office of Dietary Supplements: Black Cohosh
  77. Office of Dietary Supplements: Dietary Supplement Fact Sheets
  78. Position Papers and Consensus Statements
  79. Revised Global Consensus Statement on Menopausal Hormone Therapy
  80. Risks and Benefits of MHT
  81. Testosterone Explained – A British Menopause Society Video
  82. The North American Menopause Society Statement on Continuing Use of Systemic Hormone Therapy After Age 65
  83. Tipos de Hormonoterapia
  84. Types of Hormone Therapy
  85. Understanding Menopause – Booklet
  86. Understanding Premature & Early Menopause – Booklet
  87. Urogenital Atrophy Explained – A British Menopause Society Video
  88. Urogenital Problems
  89. Using HRT (Hormone Replacement Therapy)
  90. Vaginal Dryness
  91. Vaginal Dryness
  92. Video Gallery [Menopause, The Journal of the North American Menopause Society]
  93. Video Series-2020 – TSECs—A New Treatment for Hot Flashes and Night Sweats
  94. Video Series-2020 – What You Need To Know About Bioidentical Hormone Therapy
  95. Video Series-2021 – Treatment Options for Vaginal Dryness and Urinary Issues
  96. Video Series-2021 – What Women Need To Know About Hormone Therapies
  97. Webinars: Other Webinars – Clinician Readiness for New Therapies for Vasomotor Symptoms
  98. Webinars: Other Webinars – What To Offer for Vasomotor Symptoms When MHT Is Contraindicated [Menopausal Hormone Therapy]
  99. Webinars: Symposia – 2021 Vision: Practical Steps to Optimize Your Benefit-Risk. Discussions for A New Decade
  100. Hormone Therapy 2016 Revised Global Consensus Statement What Is Menopausal Hormone Therapy (MHT) and Is It Safe?

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Introduction. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 09 September 2021
  2. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Introduction. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 09 September 2021
  3. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Introduction. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 09 September 2021
  4. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Introduction. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 09 September 2021
  5. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section A: Benefit/Risk Profile of MHT. Climacteric, 2016;19:4:313 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 09 September 2021
  6. Menopause Glossary: V – Vasomotor Symptoms. North American Menopause Society http://www.menopause.org/for-women/menopause-glossary#V Accessed: 09 September 2021
  7. De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C. and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT. Climacteric, 2016;19:4:314 https://www.imsociety.org/wp-content/uploads/2020/08/global-consensus-hrt-2016-06.pdf Accessed: 09 September 2021

Topic Last Updated: 09 September 2021 – Topic Last Reviewed: 09 September 2021
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