“Ovarian cancer is a rare condition but all the risks and benefits of hormone therapy need to be carefully considered when treating women at menopause”.1
Umbrella
What may the Hormone Therapy and Ovarian Cancer Umbrella include?
Depending on the Source (DotS) this Umbrella may include:
- Cancer of the Ovary
- Hormone Replacement Therapy (HRT)
- Hormone Therapy (HT)
- Menopausal Hormone Replacement Therapy (MHT)
- Ovarian Cancer
Ovarian Cancer Risk
Does the use of hormone therapy (HT) increase the risk of ovarian cancer?
On page 783 in The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Ovarian Cancer – Key Points published July 2022 and “endorsed by more than 20 well-respected international organizations”, two of the key points are:
- “Current and recent use of hormone therapy is associated with a small but statistically significant risk of ovarian cancer in observational studies, principally for serous type, although there was no increase in ovarian cancer risk in women randomized to EPT in the WHI. (Level II)
- In women with a history of ovarian cancer, benefits of hormone therapy use generally outweighs risks, especially with bothersome VMS or early menopause; use of hormone therapy is not advised in women with hormone-dependent ovarian cancers, including granulosa-cell tumors and low-grade serous carcinoma. (Level II)”.3
What is EPT?
EPT can be an abbreviation for Estrogen Plus Progestogen Therapy.
What is WHI?
WHI can be an abbreviation for the Women’s Health Initiative.
What is VMS?
VMS can be an abbreviation for Vasomotor Symptoms such as hot flushes and night sweats.
What is Level II?
Level II is “Based on limited or inconsistent scientific evidence”.
Combined HRT
Does combined hormone replacement therapy (HRT) increase the risk of ovarian cancer?
In Does Hormone Replacement Therapy (HRT) Increase Cancer Risk? Does Combined HRT Increase the Risk of Cancer?, last reviewed 22 March 2023, the (United Kingdom) Cancer Research UK note:
- “Ovarian cancer: combined HRT slightly increases the risk of ovarian cancer. When HRT is stopped, the increased risk starts to go back down”.4
Oestrogen-Only HRT
Does oestrogen-only HRT increase the risk of ovarian cancer?
In Does Hormone Replacement Therapy (HRT) Increase Cancer Risk? Does Oestrogen-Only HRT Increase the Risk of Cancer?, last reviewed 22 March 2023, the (United Kingdom) Cancer Research UK note:
- “Ovarian cancer: Oestrogen-only HRT slightly increases the risk of ovarian cancer. When HRT is stopped, the increased risk starts to go back down”.4
2015 Meta-Analysis
What was the Collaborative Group on Epidemiological Studies of Ovarian Cancer’s Interpretation in their Meta-Analysis?
In Menopausal Hormone Use and Ovarian Cancer Risk: Individual Participant Meta-Analysis of 52 Epidemiological Studies – Summary (Meta-Analysis) published 12 February 2015, the Collaborative Group on Epidemiological Studies of Ovarian Cancer’s Interpretation was:

What did the Australasian Menopause Society (AMS) note about the Meta-Analysis?
In Short-Term Use of Hormone Replacement Therapy (HRT) and Ovarian Cancer Risk: Comment From AMS the AMS President’s comments note:
Women should not stop hormone therapy based on this study but if they are concerned they should discuss the findings with their doctor”.6
Health Care Provider
If I choose to use hormone therapy (HT) what is my risk of ovarian cancer?
Different women who choose to use HT can have different risks of ovarian cancer. It may therefore be in your best interest to also choose to ask your health care provider about this.
On page one in Deciding About Hormone Therapy Use, published 2022, the North American Menopause Society explain:
Health Topics A-Z
Where may I find Health Topics related to Hormone Therapy and Ovarian Cancer?
In Health Topics A-Z you may find:
Links
Where may I find Links related to Hormone Therapy and Ovarian Cancer?
Your Country may have Links similar to:
Links
This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.New or Updated
- Ask Early Menopause.org
- BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
- Bioidentical Hormones Explained – A British Menopause Society Video
- Bioidentical Hormones: Are They Safer?
- Cognitive Behaviour Therapy (CBT) for Menopausal Symptoms
- Combined Menopausal Hormone Therapy (MHT)
- Complementary Medicine Options for Menopausal Symptoms
- Compounded Bioidentical Hormone Therapy [Video]
- Deciding About Hormone Therapy
- Deciding About Hormone Therapy Use
- Does Hormone Replacement Therapy Increase Cancer Risk?
- Does Hormone Replacement Therapy Increase Cancer Risk? Does Combined HRT Increase the Risk of Cancer?
- Does Hormone Replacement Therapy Increase Cancer Risk? Does Oestrogen-Only HRT Increase the Risk of Cancer?
- Dr Gail Busby – I Forgot To Ask the Doctor – Episode 9 The Menopause
- Find A Menopause Practitioner [United States and Other]
- Find An AMS Doctor [Australasian Menopause Society i.e. Australia and New Zealand]
- Find Your Nearest BMS Menopause Specialist [British Menopause Society]
- Foundation for Women’s Cancer [United States]
- Gynecologic Cancer Awareness Month [September, United States]
- HRT
- HRT and Alternatives
- HRT – Types, Doses and Regimens
- HRT: Benefits and Risks – What You Should Know
- HRT: Summary
- Hormone Replacement Therapy
- Hormone Replacement Therapy (HRT)
- Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
- Hormone Replacement Therapy (HRT): Alternatives
- Hormone Replacement Therapy (HRT): Risks
- Hormone Therapy: Is It Right for You?
- Hot Flashes
- Hot Flashes
- Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
- How To Find Relief for Hot Flashes At Night
- Index To Drug-Specific Information [United States]
- Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
- Joint RCOG/BMS Statement: Lancet Study Examines Use of HRT and Ovarian Cancer Risk
- Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?]
- Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Treating Menopause Symptoms [+ Video: Does the Menopause Happen Suddenly?]
- Managing Menopausal Symptoms—Hormone Replacement Therapy Is Not the Only Option!
- Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video Courtesy: Mayo Clinic News Network]
- Mayo Clinic Minute: How Lifestyle Changes May Help Manage Menopause Symptoms [+ Video]
- Menopausal Hormone Therapy
- Menopausal Hormone Therapy and Breast Cancer Risk
- Menopausal Hormone Therapy and Cancer
- Menopausal Hormone Therapy and Venous Thromboembolism
- Menopausal Hormone Use and Ovarian Cancer Risk: Individual Participant Meta-Analysis of 52 Epidemiological Studies
- Menopause
- Menopause
- Menopause & Herbs
- Menopause Management Options: Menopausal Hormone Therapy (MHT)
- Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
- Menopause Map: Downloadable Resources – My Personal Path Print Tools: Symptom Tracker
- Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
- Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
- Menopause Patient Information [Videos] 4. The Different Types of HRT
- Menopause Patient Information [Videos] 5. Lifestyle Advice In Menopause & Perimenopause
- Menopause Preparedness Toolkit Video Series: Treating Vasomotor Symptoms of Menopause
- Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
- Menopause Treatment
- Menopause Treatments: What Works, What Doesn’t
- Menopause: Diagnosis & Treatment
- Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
- Menopause: Menopause – Hormone Treatments
- National Center for Complementary and Integrative Health: Herbs At A Glance
- National Center for Complementary and Integrative Health: Know the Science: How Medications and Supplements Can Interact
- National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
- National Center for Complementary and Integrative Health: Natural Doesn’t Necessarily Mean Safer, or Better
- Natural Remedies To Help Manage Perimenopause Symptoms
- Natural Therapies & Supplements
- Navigating Menopause: Expert Insights and Solutions | Dr Susan Davis | The Proof Podcast EP 245
- Non-Estrogen Treatments for Menopausal Symptoms
- OCCAM Office of Cancer Complementary and Alternative Medicine [National Cancer Institute, United States]
- Oestrogen Only Menopausal Hormone Therapy
- Ovarian Cancer
- Ovarian Cancer
- Ovarian Cancer
- Ovarian Cancer Risk Factors
- Ovarian Cancer Risk and Causes
- Ovarian Cancer: How Diet, Nutrition and Physical Activity Affect Ovarian Cancer Risk
- Ovarian Cancer: What Can I Do To Reduce My Risk?
- Short-Term Use of Hormone Replacement Therapy (HRT) and Ovarian Cancer Risk
- Signs and Symptoms
- Statement From Dr Rodney Baber, President IMS Re the Recent Report on Ovarian Cancer Risk Associated With HRT Usage Published In The Lancet, 13th February 2015
- Study IDs Non-Hormonal Options for Menopause Symptoms
- The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement
- Tips To Help Manage Menopause Symptoms
- Types of Hormone Therapy
- Using Natural Therapies In the Menopause Transition – Webinar
- Video Series-2020: What You Need To Know About Bioidentical Hormone Therapy
- Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
- Video Series-2023: Lifestyle Modification and Prevention of Breast Cancer
- Videos and Podcasts: Videos – Interviews: How Do I Deal With the Menopause After A Diagnosis of Gynaecological Cancer
- What Are the Benefits and Risks of HRT?
- What Is My Risk of Ovarian Cancer?
- Why Didn’t Anyone Tell Me This? Episode 3: Dr Annice Mukherjee: Your Essential Menopause Toolkit
- What Is Ovarian Cancer?
- World Ovarian Cancer Day: What Is World Ovarian Cancer Day?
Sources
Where may I find the Sources quoted?
You may find the Sources quoted at:
Sources
- Short-Term Use of Hormone Replacement Therapy (HRT) and Ovarian Cancer Risk: Comment From AMS. Content Updated: 17 February 2015. Australasian Menopause Society https://www.menopause.org.au/hp/news/729-short-term-use-of-hrt-and-ovarian-cancer-risk Accessed: 27 March 2023
- The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Ovarian Cancer – Key Points. July 2022:783. North American Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 27 March 2023
- Collaborative Group on Epidemiological Studies of Ovarian Cancer. Menopausal Hormone Use and Ovarian Cancer Risk: Individual Participant Meta-Analysis of 52 Epidemiological Studies – Summary: Interpretation. Lancet Volume 385, ISSUE 9980, P1835-1842, May 09, 2015 https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(14)61687-1/fulltext Accessed: 27 March 2023
- Does Hormone Replacement Therapy (HRT) Increase Cancer Risk? Does Combined HRT Increase the Risk of Cancer? Last Reviewed 22 March 2023. Cancer Research UK https://www.cancerresearchuk.org/about-cancer/causes-of-cancer/hormones-and-cancer/does-hormone-replacement-therapy-increase-cancer-risk Accessed: 27 March 2023
- Does Hormone Replacement Therapy (HRT) Increase Cancer Risk? Does Oestrogen-Only HRT Increase the Risk of Cancer? Last Reviewed 22 March 2023. Cancer Research UK https://www.cancerresearchuk.org/about-cancer/causes-of-cancer/hormones-and-cancer/does-hormone-replacement-therapy-increase-cancer-risk Accessed: 27 March 2023
- Joint RCOG/BMS Statement: Lancet Study Examines Use of HRT and Ovarian Cancer Risk. Royal College of Obstetricians and Gynaecologists. 13 February 2015 https://thebms.org.uk/2015/02/joint-rcogbms-statement-lancet-study-examines-use-of-hrt-and-ovarian-cancer-risk/ Accessed: 27 March 2023
- Short-Term Use of Hormone Replacement Therapy (HRT) and Ovarian Cancer Risk: Comment From AMS. Content Updated: 17 February 2015. Australasian Menopause Society https://www.menopause.org.au/hp/news/729-short-term-use-of-hrt-and-ovarian-cancer-risk Accessed: 27 March 2023
- Deciding About Hormone Therapy Use. 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 27 March 2023