Hormone Therapy and Lung Cancer

“Current or ever HRT use
is partly correlated with
the decreased incidence of lung cancer in women”.1

Umbrella
What may the Hormone Therapy and Lung Cancer Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Cancer of the Lung
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Lung Cancer
  • Menopausal Hormone Therapy (MHT)

Incidence

Is there an association between menopausal hormone therapy (MHT) and the incidence of lung cancer in women?

In The Association Between Different Hormone Replacement Therapy Use and the Incidence of Lung Cancer: A Systematic Review and Meta-Analysis, published 28 February 2022, the authors note:

Hormone Therapy and Lung Cancer“Conclusions: Current or ever HRT use is partly correlated with the decreased incidence of lung cancer in women. Concerns about the incidence of lung cancer can be reduced when perimenopausal and postmenopausal women use current HRT to reduce menopausal symptoms. Meanwhile, given the roles of hormone receptors and relevant genes single nucleotide polymorphism (SNPs) among females, HRT use should be cautiously administered and individualized”.2

In The Influence of Hormone Replacement Therapy on Lung Cancer Incidence and Mortality, published 05 November 2019, the authors note:

“Conclusions: These data represent among the largest prospective cohorts suggesting HRT use may have a protective effect on the development of NSCLC among women; the physiological basis of this effect merits further study; however, the results may influence discussion surrounding HRT use in women”.3

Health Care Provider

If I choose to use HT what is my risk of lung cancer?

Different women who choose to use HT can have different risks of lung cancer. It may therefore be in your best interest to also choose to talk to your health care provider about this

In The 2022 Hormone Therapy Position Statement of The North American Menopause Society, published July 2022, the North American Menopause Society elaborate on:

“Hormone therapy remains the most effective treatment for vasomotor symptoms (VMS) and the genitourinary syndrome of menopause and has been shown to prevent bone loss and fracture. The risks of hormone therapy differ depending on type, dose, duration of use, route of administration, timing of initiation, and whether a progestogen is used. Treatment should be individualized using the best available evidence to maximize benefits and minimize risks, with periodic reevaluation of the benefits and risks of continuing therapy”.4

Health Topics A-Z

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In Health Topics A-Z you may find:

Health Topics A-Z

Links

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Links

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New or Updated

  1. Askearlymenopause.org [Ask EM] [+ Video: What Is Early Menopause?]
  2. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  3. Bioidentical Custom Compounded Hormone Therapy
  4. Bioidentical Hormone Therapy
  5. Bioidentical Hormones Explained – A British Menopause Society Video
  6. Bioidentical Hormones: Are They Safer?
  7. Combined Menopausal Hormone Therapy (MHT)
  8. Complementary and Alternative Therapies Explained – A British Menopause Society Video
  9. Deciding About Hormone Therapy
  10. Deciding About Hormone Therapy Use
  11. Decidir Sobre La Hormonoterapia
  12. Despite Misperceptions, Hormone Therapy May Actually Reduce Risk of Lung Cancer
  13. Dr Gail Busby – I Forgot To Ask the Doctor – Episode 9 The Menopause
  14. Does Hormone Replacement Therapy Increase Cancer Risk?
  15. EMAS Menopause Essentials
  16. Five Reasons Why Calling A Quitline Can Be Key To Your Success
  17. HRT & Menopause Extra
  18. HRT – Types, Doses and Regimens
  19. HRT: Benefits and Risks
  20. Hormone Replacement Therapy
  21. Hormone Replacement Therapy (HRT)
  22. Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
  23. Hormone Replacement Therapy (HRT): Types
  24. Hormone Therapy: Is It Right for You?
  25. Hot Flashes: Manage Without Medication?
  26. Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
  27. How Menopause Impacts Your Health
  28. How To Quit Smoking
  29. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [+ Video: Is HRT Bad for You?]
  30. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Signs and Symptoms [+ Video: Talking Menopause With Your GP]
  31. Lung Cancer
  32. Lung Cancer
  33. Mayo Clinic Minute: Help With Hot Flashes Due To Menopause [+ Video]
  34. Mayo Clinic Minute: How Lifestyle Changes May Help Manage Menopause Symptoms [+ Video]
  35. Menopausal Hormone Therapy
  36. Menopausal Hormone Therapy and Venous Thromboembolism
  37. Menopausal Hormone Therapy, Heart Disease and Stroke
  38. Menopause
  39. Menopause
  40. Menopause & Herbs
  41. Menopause FAQs: Hormone Therapy for Menopause Symptoms
  42. Menopause Management Options: Menopausal Hormone Therapy (MHT)
  43. Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
  44. Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
  45. Menopause Preparedness Toolkit Video Series: Lifestyle Tips for Menopause Wellness
  46. Menopause Patient Information [Videos] 4. The Different Types of HRT
  47. Menopause Patient Information [Videos] 5. Lifestyle Advice In Menopause & Perimenopause
  48. Menopause Preparedness Toolkit Video Series: Treating Vasomotor Symptoms of Menopause
  49. Menopause Symptoms: Mayo Clinic Expert Outlines Hormone and Nonhormonal Therapies
  50. Menopause Treatment
  51. Menopause Treatments: What Works, What Doesn’t
  52. Menopause: Diagnosis & Treatment
  53. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  54. National Center for Complementary and Integrative Health: Herbs At A Glance
  55. National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
  56. Non-Estrogen Treatments for Menopausal Symptoms
  57. Oestrogen Only Menopausal Hormone Therapy
  58. Quit Smoking
  59. Quit Smoking
  60. Quit Smoking: Stop Smoking Without Putting on Weight
  61. Quit Tobacco Today!
    [+ Video: Meet Florence – She Can Help You Quit Tobacco!]
  62. Risks and Benefits of MHT
  63. Smokefree.gov [United States]
  64. Smokefreewomen [United States]
  65. Smokefreewomen [United States]: Smokefree Apps
  66. Smoking and Cancer
  67. The 2022 Hormone Therapy Position Statement of The North American Menopause Society
  68. The Association Between Different Hormone Replacement Therapy Use and the Incidence of Lung Cancer: A Systematic Review and Meta-Analysis
  69. The Influence of Hormone Replacement Therapy on Lung Cancer Incidence and Mortality
  70. Tips To Help Manage Menopause Symptoms
  71. Types of Hormone Therapy
  72. Using Natural Therapies In the Menopause Transition – Webinar
  73. Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
  74. Video Series-2022: Perimenopause, Signs, Symptoms, and Solutions
  75. Webinars: Previous – Breast Cancer
  76. What Everyone Should Know About Menopause Symptoms
  77. Why Didn’t Anyone Tell Me This? Episode 3: Dr Annice Mukherjee: Your Essential Menopause Toolkit
  78. Women.smokefree.gov [Smokefreewomen, United States]

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Wen, H., Lin, X., Dun, D. The Association Between Different Hormone Replacement Therapy Use and the Incidence of Lung Cancer: A Systematic Review and Meta-Analysis: Conclusions. 28 February 2022 https://jtd.amegroups.com/article/view/61565/html Accessed: 20 February 2023
  2. Wen, H., Lin, X., Dun, D. The Association Between Different Hormone Replacement Therapy Use and the Incidence of Lung Cancer: A Systematic Review and Meta-Analysis: Conclusions. 28 February 2022 https://jtd.amegroups.com/article/view/61565/html Accessed: 20 February 2023
  3. Titan, A. L., He, H. Lui, N., Liou, D., Berry, M., Shrager, J. B., Backhus, L. M. The Influence of Hormone Replacement Therapy on Lung Cancer Incidence and Mortality: Conclusions. 05 November 2019https://www.jtcvs.org/article/S0022-5223(19)32348-7/fulltext Accessed: 20 February 2023
  4. The 2022 Hormone Therapy Position Statement of The North American Menopause Society. July 2022. North American Menopause Society https://journals.lww.com/menopausejournal/Abstract/2022/07000/The_2022_hormone_therapy_position_statement_of_The.4.aspx Accessed: 20 February 2023

Topic Last Updated: 02 March 2023 – Topic Last Reviewed: 20 February 2023
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