Hormone Therapy and SERMs

“SERMs is “shorthand” for a class of drug called
selective oestrogen receptor modulators.
They are a versatile group of drugs that can be used to…”.1

Umbrella
What may the Hormone Therapy and SERMs Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Bazedoxifene (BZA)
  • Evista (chemical name: Raloxifene (RLX))
  • Fareston (chemical name: Toremifene)
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Oestrogen Agonist/Antagonists
  • Ospemifene
  • Selective Estrogen Receptor Modulators (SERMs)
  • Tamoxifen (TAM) (brand name: Soltamox)

Definition

What is SERMs?

DotS the definition of SERMs may vary. The Australasian Menopause Society’s (AMS) definition is:

“SERMs is “shorthand” for a class of drug called selective oestrogen receptor modulators”.2

Treatment

What can SERMs be used to treat?

In SERMs – Their Role In Menopause Management the AMS explain:

“They are a versatile group of drugs that can be used to treat/ prevent a number of conditions such as osteoporosis, infertility and hormone responsive cancers. Within the SERM class, different compounds have differing agonist or antagonist effects at the oestrogen receptor in different tissues, therefore they are “selective””.3

Raloxifene

What is Raloxifene?

On page two in SERMs FAQs – Q: I Have Low Bone Mineral Density. Is There A SERM That Can Help? the North American Menopause Society (NAMS) elaborate on:

“A: Raloxifene (marketed as Evista), a mixed estrogen activator (agonist) and blocker (antagonist), acts as an activator in bone and as a blocker in the uterus and breast. It is FDA approved to prevent and treat osteoporosis and to reduce the risk of invasive breast cancer in women who have osteoporosis or who are at high risk of breast cancer. Its benefits include slowing the process of bone loss and rebuilding (called bone turnover), increasing bone density, and reducing the risk of vertebral fractures caused by osteoporosis”.4

What is FDA?

FDA can be an abbreviation for the (United States) Food and Drug Administration.

SERMs FAQs

Is there a SERMs FAQs (Frequently Asked Questions)?

In What Selective Estrogen Receptor Modulators (SERMs) Can Do for You: Frequently Asked Questions About SERMs you can “get answers to the 12-most frequently asked questions about SERMs” in SERMs FAQs.

Health Care Provider

What if I choose to use SERMs?

If you choose to use SERMs, it may be in your best interest to also choose to talk to your health care provider about this.

On page two in SERMS FAQs: Q: So What Is the Bottom Line? the NAMS explain:

Hormone Therapy and SERMs

“A: Talk to your clinician about whether a SERM might be right for you if you are experiencing hot flashes and have a history of breast cancer, have been told you have low bone density, want to avoid bleeding or change in breast density but need relief from hot flashes, or sex is painful for you. Write your questions and all your symptoms down before your visit to discuss with your clinician. There is help out there”.5

Health Topics A-Z

Where may I find Health Topics related to Hormone Therapy and SERMs?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy and SERMs?

Your Country may have Links similar to:

Links

This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.

New or Updated

  1. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  2. Bioidentical Custom Compounded Hormone Therapy
  3. Bioidentical Hormone Therapy
  4. Bioidentical Hormones Explained – A British Menopause Society Video
  5. Bioidentical Hormones: Are They Safer?
  6. Breastcancer.org [United States]
  7. Combined Menopausal Hormone Therapy (MHT)
  8. Complementary and Alternative Therapies Explained – A British Menopause Society Video
  9. Deciding About Hormone Therapy Use
  10. Does Osteoporosis Run In Your Family?
  11. Dr Gail Busby – I Forgot To Ask the Doctor – Episode 9 The Menopause
  12. EMAS Menopause Essentials
  13. EMAS Replay [Webinars: Multiply Languages]
  14. Evista
  15. Evista for Osteoporosis
  16. HRT
  17. HRT and Alternatives
  18. HRT – Types, Doses and Regimens
  19. HRT: Benefits and Risks
  20. Hormonal Therapy
  21. Hormone Replacement Therapy
  22. Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
  23. Hormone Replacement Therapy (HRT): Benefits and Risks
  24. Hormone Therapy: Is It Right for You?
  25. Hot Flashes: What Can I Do? [+ Video: What Are the Signs and Symptoms of Menopause?]
  26. How Menopause Impacts Your Health
  27. International Osteoporosis Foundation: About Osteoporosis
  28. Is There Still A Role for SERMs In Menopause Management?
  29. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  30. Later Years (Around 50 Years and Over): Menopause and Post Menopause Health – Hormone Replacement Therapy (HRT) [Other Languages and Formats] [+ Video: Is HRT Bad for You?]
  31. Lifestyle and Behaviour Changes for Menopausal Symptoms
  32. Lifestyle and Behavioural Modifications for Menopausal Symptoms
  33. Menopausal Hormone Therapy
  34. Menopause
  35. Menopause
  36. Menopause
  37. Menopause
  38. Menopause
  39. Menopause
  40. Menopause
  41. Menopause & Herbs
  42. Menopause Explained – A British Menopause Society Video
  43. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  44. Menopause Management Option
  45. Menopause Patient Information [Videos] 2. Talking To Your GP About Menopause
  46. Menopause Patient Information [Videos] 3. The Risks & Benefits of HRT
  47. Menopause Patient Information [Videos] 4. The Different Types of HRT
  48. Menopause Preparedness Toolkit Video Series: Common Conditions Associated With Menopause and Midlife
  49. Menopause Preparedness Toolkit Video Series: Treating Vasomotor Symptoms of Menopause
  50. Menopause Treatments: What Works, What Doesn’t
  51. Menopause and Your Health
  52. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  53. National Center for Complementary and Integrative Health: Know the Science: How Medications and Supplements Can Interact
  54. National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
  55. National Osteoporosis Month [May, United States]
  56. Natural Therapies & Supplements
  57. NonHormonal Treatments for Menopausal Symptoms
  58. Oestrogen Only Menopausal Hormone Therapy
  59. Optimising the Menopause Transition: Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  60. Osteoporosis
  61. Osteoporosis: Bone Health Following the Menopause
  62. Raloxifene
  63. Raloxifene (Oral Route)
  64. Risks and Benefits of MHT
  65. SERMs FAQs
  66. SERMs – Their Role In Menopause Management
  67. The Beneficial and Adverse Effects of Raloxifene In Menopausal Women: A Mini Review
  68. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement
  69. Tips To Help Manage Menopause Symptoms
  70. Using Natural Therapies In the Menopause Transition – Webinar
  71. Video Series-2021: What Women Need To Know About Hormone Therapies
  72. Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
  73. Videos and Podcasts: Interviews and Podcasts – Interviews: Prevention of Chronic Diseases In Women: Where Does MHT Fit In?
  74. Videos and Podcasts: World Menopause Day 2021 – Interviews: Bone Health
  75. Videos and Podcasts: World Menopause Day 2021 – Interviews: Bone Health What Why and How
  76. Webinars: Previous – The Early Menopausal Patient
  77. Webinars: Previous – Update on Bone Health
  78. What Is Osteoporosis and What Causes It? [+ Video: What Is Osteoporosis]
  79. What Selective Estrogen Receptor Modulators (SERMs) Can Do for You: Discussion About SERMs With the Experts [Video]
  80. World Menopause Day: Patient Information Leaflet: Update on Bone Health [Multiply Languages]
    Hormone Therapy and SERMs

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. SERMs – Their Role In Menopause Management. Content Updated May 2017. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 01 January 2023
  2. SERMs – Their Role In Menopause Management. Content Updated May 2017. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 01 January 2023
  3. SERMs – Their Role In Menopause Management. Content Updated May 2017. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 01 January 2023
  4. SERMs FAQs – Q: I Have Low Bone Mineral Density. Is There A SERM That Can Help? Page 2. North American Menopause Society https://www.menopause.org/docs/default-source/for-women/serms-faqs.pdf Accessed: 01 January 2023
  5. SERMs FAQs – Q: So What Is the Bottom Line? Page 3. North American Menopause Society https://www.menopause.org/docs/default-source/for-women/serms-faqs.pdf Accessed: 01 January 2023
Topic Last Updated: 01 January 2023 – Topic Last Reviewed: 01 January 2023

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