Hormone Therapy and SERMs

“SERMs is “shorthand” for a class of drug called
selective oestrogen receptor modulators.
They are a versatile group of drugs that can be used to…”.1

Umbrella
What may the Hormone Therapy and SERMs Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Evista (chemical name: Raloxifene)
  • Fareston (chemical name: Toremifene)
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Oestrogen Agonist/Antagonists
  • Selective Estrogen Receptor Modulators (SERMs)
  • Tamoxifen (brand name: Soltamox)

Definition

What is SERMs?

DotS the definition of SERMs may vary. The Australasian Menopause Society’s (AMS) definition is:

“SERMs is “shorthand” for a class of drug called selective oestrogen receptor modulators”.2

Treatment

What can SERMs be used to treat?

In SERMs – Their Role In Menopause Management the AMS explain:

“They are a versatile group of drugs that can be used to treat/ prevent a number of conditions such as osteoporosis, infertility and hormone responsive cancers. Within the SERM class, different compounds have differing agonist or antagonist effects at the oestrogen receptor in different tissues, therefore they are “selective””.3

Raloxifene

What is Raloxifene?

On page two in SERMs FAQs – Q: I Have Low Bone Mineral Density. Is There A SERM That Can Help? the North American Menopause Society (NAMS) elaborate on:

“A: Raloxifene (marketed as Evista), a mixed estrogen activator (agonist) and blocker (antagonist), acts as an activator in bone and as a blocker in the uterus and breast. It is FDA approved to prevent and treat osteoporosis and to reduce the risk of invasive breast cancer in women who have osteoporosis or who are at high risk of breast cancer. Its benefits include slowing the process of bone loss and rebuilding (called bone turnover), increasing bone density, and reducing the risk of vertebral fractures caused by osteoporosis”.4

What is FDA?

FDA can be an abbreviation for the (United States) Food and Drug Administration.

SERMs FAQs

Is there a SERMs FAQs (Frequently Asked Questions)?

In What Selective Estrogen Receptor Modulators (SERMs) Can Do for You: Frequently Asked Questions About SERMs you can “get answers to the 12-most frequently asked questions about SERMs” in SERMs FAQs.

Health Care Provider

What if I choose to use SERMs?

If you choose to use SERMs, it may be in your best interest to also choose to talk to your health care provider about this.

On page two in SERMS FAQs: Q: So What Is the Bottom Line? the NAMS explain:

Hormone Therapy and SERMs

“A: Talk to your clinician about whether a SERM might be right for you if you are experiencing hot flashes and have a history of breast cancer, have been told you have low bone density, want to avoid bleeding or change in breast density but need relief from hot flashes, or sex is painful for you. Write your questions and all your symptoms down before your visit to discuss with your clinician. There is help out there”.5

Health Topics A-Z

Where may I find Health Topics related to Hormone Therapy and SERMs?

In Health Topics A-Z you may find:

Health Topics A-Z

Links

Where may I find Links related to Hormone Therapy and SERMs?

Your Country may have Links similar to:

Links

This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directory’s Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.

  1. BMS & WHC’s 2020 Recommendations on Hormone Replacement Therapy In Menopausal Women
  2. Bioidentical Custom Compounded Hormone Therapy
  3. Bioidentical Hormone Therapy
  4. Bioidentical Hormones Explained – A British Menopause Society Video
  5. Bioidentical Hormones: Are They Safer?
  6. Breastcancer.org [United States]
  7. Combined Menopausal Hormone Therapy (MHT)
  8. Complementary Medicine Options for Menopausal Symptoms
  9. Complementary and Alternative Therapies Explained – A British Menopause Society Video
  10. Deciding About Hormone Therapy Use
  11. Does Osteoporosis Run In Your Family?
  12. EMAS Menopause Essentials
  13. EMAS Replay [Webinars]
  14. Evista
  15. Evista for Osteoporosis
  16. HRT
  17. HRT and Alternatives
  18. HRT: Benefits and Risks
  19. Hormonal Therapy
  20. Hormone Replacement Therapy
  21. Hormone Replacement Therapy (HRT) Explained – A British Menopause Society Video
  22. Hormone Replacement Therapy (HRT): Benefits and Risks
  23. Hormone Therapy: Is It Right for You?
  24. How Menopause Impacts Your Health
  25. International Osteoporosis Foundation: About Osteoporosis
  26. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  27. Lifestyle and Behaviour Changes for Menopausal Symptoms
  28. Lifestyle and Behavioural Modifications for Menopausal Symptoms
  29. Menopausal Hormone Therapy
  30. Menopause
  31. Menopause
  32. Menopause
  33. Menopause
  34. Menopause
  35. Menopause
  36. Menopause
  37. Menopause & Herbs
  38. Menopause Explained – A British Menopause Society Video
  39. Menopause Map: Downloadable Resources – My Personal Path Print Tools: Questions for Your Health Care Provider
  40. Menopause Management Options
  41. Menopause Preparedness Toolkit Video Series: Common Conditions Associated With Menopause and Midlife
  42. Menopause and Your Health
  43. Menopause: Diagnosis and Management – Information for the Public: Questions To Ask About Menopause [NICE Guideline]
  44. Menopause: Medicines To Help You
  45. Menopause: Menopause – Hormone Treatments
  46. National Center for Complementary and Integrative Health: Know the Science: How Medications and Supplements Can Interact
  47. National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth
  48. National Osteoporosis Month [May, United States]
  49. Natural Therapies & Supplements
  50. NonHormonal Treatments for Menopausal Symptoms
  51. Oestrogen Only Menopausal Hormone Therapy
  52. Optimising the Menopause Transition: Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause
  53. Osteoporosis
  54. Osteoporosis: Bone Health Following the Menopause
  55. Raloxifene
  56. Raloxifene (Oral Route)
  57. Risks and Benefits of MHT
  58. SERMs FAQs
  59. SERMs – Their Role In Menopause Management
  60. The Beneficial and Adverse Effects of Raloxifene In Menopausal Women: A Mini Review
  61. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement
  62. Using Natural Therapies In the Menopause Transition – Webinar
  63. Video Series-2021: What Women Need To Know About Hormone Therapies
  64. Video Series-2022: Hormone Therapy: Understanding the Risks and Benefits
  65. Videos and Podcasts: Interviews and Podcasts – Interviews: Prevention of Chronic Diseases In Women: Where Does MHT Fit In?
  66. Videos and Podcasts: World Menopause Day 2021 – Interviews: Bone Health
  67. Videos and Podcasts: World Menopause Day 2021 – Interviews: Bone Health What Why and How
  68. Webinars: Previous – The Early Menopausal Patient
  69. Webinars: Previous – Update on Bone Health
  70. What Is Osteoporosis and What Causes It? [+ Video: What Is Osteoporosis]
  71. What Selective Estrogen Receptor Modulators (SERMs) Can Do for You: Discussion About SERMs With the Experts [Video]
  72. World Menopause Day: Patient Information Leaflet: Update on Bone Health [Multiply Languages]
    Hormone Therapy and SERMs

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. SERMs – Their Role In Menopause Management. Content Updated May 2017. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 18 October 2022
  2. SERMs – Their Role In Menopause Management. Content Updated May 2017. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 18 October 2022
  3. SERMs – Their Role In Menopause Management. Content Updated May 2017. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 18 October 2022
  4. SERMs FAQs – Q: I Have Low Bone Mineral Density. Is There A SERM That Can Help? Page 2. North American Menopause Society https://www.menopause.org/docs/default-source/for-women/serms-faqs.pdf Accessed: 18 October 2022
  5. SERMs FAQs – Q: So What Is the Bottom Line? Page 3. North American Menopause Society https://www.menopause.org/docs/default-source/for-women/serms-faqs.pdf Accessed: 18 October 2022
Topic Last Updated: 18 October 2022 – Topic Last Reviewed: 18 October 2022

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