“SERMs is “shorthand” for a class of drug called
selective oestrogen receptor modulators.
They are a versatile group of drugs that can be used to…”.1

Umbrella
What may the Hormone Therapy and SERMs Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Bazedoxifene (BZA)
  • Evista (chemical name: Raloxifene (RLX))
  • Fareston (chemical name: Toremifene)
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Oestrogen Agonist/Antagonists
  • Ospemifene
  • Selective Estrogen Receptor Modulators (SERMs)
  • Tamoxifen (TAM) (brand name: Soltamox)

SERMs

What are SERMs?

In SERMs – Their Role In Menopause Management, content updated May 2023, the Australasian Menopause Society (AMS) explain:

“SERMs is “shorthand” for a class of drug called selective oestrogen receptor modulators”.2

Treatment

What can SERMs be used to treat?

In SERMs – Their Role In Menopause Management the AMS elaborate on:

“They are a versatile group of drugs that can be used to treat/ prevent several conditions such as osteoporosis, infertility and hormone responsive cancers. Within the SERM class, different compounds have differing agonist or antagonist effects at the oestrogen receptor in different tissues, therefore they are “selective””.3

Different Kinds of SERMs

What are different kinds of SERMs?

In SERMs – Their Role In Menopause Management: Different Kinds of SERMs the AMS include:

  • “Tamoxifen…
  • Raloxifene…
  • Bazedoxifene…
  • Ospemifene…
  • Lasofoxifene…”.4

Health Care Provider

What if I choose to use SERMs?

If you choose to use SERMs, it may be in your best interest to also choose to talk to your health care provider about this.

On page two in SERMS FAQs: Q: So What Is the Bottom Line? the NAMS explain:

Hormone Therapy and SERMs“A: Talk to your clinician about whether a SERM might be right for you if you are experiencing hot flashes and have a history of breast cancer, have been told you have low bone density, want to avoid bleeding or change in breast density but need relief from hot flashes, or sex is painful for you. Write your questions and all your symptoms down before your visit to discuss with your clinician. There is help out there”.5

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Links

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Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. SERMs – Their Role In Menopause Management. Content Updated May 2023. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 23 August 2023
  2. SERMs – Their Role In Menopause Management. Content Updated May 2023. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 23 August 2023
  3. SERMs – Their Role In Menopause Management. Content Updated May 2023. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 23 August 2023
  4. SERMs – Their Role In Menopause Management: Different Kinds of SERMs. Content Updated May 2023. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/971-serms-their-role-in-menopause-management Accessed: 23 August 2023
  5. SERMs FAQs – Q: So What Is the Bottom Line? Page 3. North American Menopause Society https://www.menopause.org/docs/default-source/for-women/serms-faqs.pdf Accessed: 23 August 2023
Topic Last Updated: 23 August 2023 – Topic Last Reviewed: 23 August 2023

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