“One elevated FSH level is not enough to confirm
menopause. More important, a low FSH level in a woman
who is having hot flashes and changing periods…”.1

Umbrella
What may the Follicle Stimulating Hormone (FSH) Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Follicle Stimulating Hormone (FSH)

Definition

What is follicle stimulating hormone (FSH)?

DotS the definition of FSH may vary. The (United States) Endocrine Society’s definition is:

“Follicle stimulating hormone (FSH)—In women, FSH helps control the menstrual cycle and the production of eggs by the ovaries. The amount of FSH varies throughout a woman’s menstrual cycle and is highest just before she ovulates. Problems with FSH release can contribute to female infertility. In men, FSH helps control the production of sperm”.2

The North American Menopause Society’s (NAMS) definition is:

“Follicle-stimulating hormone (FSH). A hormone produced by the pituitary gland (located at the base of the brain). In women, FSH stimulates the growth of ovarian follicles (the small cysts that hold the eggs) and the supporting cells responsible for the growth and nurturing of the egg. FSH also stimulates production of estrogen by the ovaries. When estrogen production is low (after menopause), FSH levels will be high”.3

FSH Blood Test

What is a FSH blood test?

In Follicle-Stimulating Hormone (FSH) Blood Test the (United States) MedlinePlus explain:

“The follicle stimulating hormone (FSH) blood test measures the level of FSH in blood. FSH is a hormone released by the pituitary gland, located on the underside of the brain”.4

Tests or Not

Are tests typically needed to diagnose menopause?

In Menopause: Diagnosis & Treatment – Diagnosis the (United States) Mayo Clinic note:

“Tests typically aren’t needed to diagnose menopause”.5

Menopause

What may it be important to note about menopause and FSH blood levels?

In Diagnosing Menopause: Symptom Assessment and Diagnosis At Perimenopause and Menopause the Australasian Menopause Society explain:

“It is important to explain to women that the blood tests of FSH/oestradiol can fluctuate on a daily basis and therefore are not useful or necessary. It is especially unhelpful to do hormone blood tests while women are on MHT/OCP – symptoms, not blood levels, guide therapy”.6

Follicle Stimulating Hormone (FSH)What is a MHT?

MHT can be an abbreviation for Menopause Hormone Therapy.

What is a OCP?

MHT can be an abbreviation for the Oral Contraceptive Pill.

The NAMS also note:

“…a single FSH level can be misleading in perimenopause because estrogen production does not fall at a steady rate from day to day. Instead, both estrogen and FSH levels can vary greatly during perimenopause. One elevated FSH level is not enough to confirm menopause. More important, a low FSH level in a woman who is having hot flashes and changing periods does not eliminate the likelihood that she is still in perimenopause”.7

On page one in NICE: Menopause, Diagnosis and Management – From Guideline To Practice Guideline Summary: Ten Key Messages the British Menopause Society explain:

2 Diagnosis
“Blood tests are rarely required to diagnose perimenopause or menopause in women aged over 45 and should not be taken. While measurement of FSH has often been used in the past to diagnose perimenopause or menopause, the level fluctuates significantly and bears no correlation with severity or duration of symptoms or to requirement for treatment. Reducing inappropriate use of testing FSH levels will produce savings in terms of cost of test, time for further consultation to discuss the results and will reduce delay in commencing agreed management”.8

Not Valid

When is a FSH test not valid?

The NAMS note:

“Also, if a woman is using certain hormone therapies (such as birth control pills), a FSH test is not valid”.9

Over-the-Counter Tests

Can over-the-counter home tests really tell you whether or not you’re definitely in a stage of menopause?

In Menopause: Diagnosis & Treatment – Diagnosis the (United States) Mayo Clinic note:

“Over-the-counter home tests to check FSH levels in your urine are available. The tests could tell you whether you have elevated FSH levels and might be in perimenopause or menopause. But, since FSH levels rise and fall during the course of your menstrual cycle, home FSH tests can’t really tell you whether or not you’re definitely in a stage of menopause”.10

Health Care Provider

What if I would like to find out more about FSH?

If you would like to find out more about FSH, it may be in your best interest to choose to talk to your health care provider about this. Together you can discuss your options and if required, agree on who may be the most appropriate health care provider to help you.

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Links

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Sources

Where may I find the Sources quoted?

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Sources

  1. How Do I Know I’m In Menopause? What About Follicle-Stimulating Hormone Testing? North American Menopause Society https://www.menopause.org/for-women/menopauseflashes/menopause-symptoms-and-treatments/how-do-i-know-i’m-in-menopause- Accessed: 07 May 2024
  2. Glossary. Endocrine Society https://www.endocrine.org/news-and-advocacy/news-room/glossary Accessed: 07 May 2024
  3. Menopause Glossary: F – Follicle-Stimulating Hormone (FSH). North American Menopause Society https://www.menopause.org/for-women/menopause-glossary#F Accessed: 07 May 2024
  4. Follicle-Stimulating Hormone (FSH) Blood Test. Review Date: 23 August 2023. MedlinePlus https://www.nlm.nih.gov/medlineplus/ency/article/003710.htm Accessed: 07 May 2024
  5. Menopause: Diagnosis & Treatment – Diagnosis. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/menopause/diagnosis-treatment/drc-20353401″ Accessed: 07 May 2024
  6. Diagnosing Menopause: Symptom Assessment and Diagnosis At Perimenopause and Menopause. Content Created May 2022. Australasian Menopause Society https://www.menopause.org.au/hp/gp-hp-resources/diagnosing-menopause Accessed: 07 May 2024
  7. How Do I Know I’m In Menopause? What About Follicle-Stimulating Hormone Testing? North American Menopause Society https://www.menopause.org/for-women/menopauseflashes/menopause-symptoms-and-treatments/how-do-i-know-i’m-in-menopause-Accessed: 07 May 2024
  8. NICE: Menopause, Diagnosis and Management – From Guideline To Practice Guideline Summary: Ten Key Messages 2022:1. British Menopause Society https://thebms.org.uk/wp-content/uploads/2022/12/09-BMS-TfC-NICE-Menopause-Diagnosis-and-Management-from-Guideline-to-Practice-Guideline-Summary-NOV2022-A.pdf Accessed: 07 May 2024
  9. How Do I Know I’m In Menopause? What About Follicle-Stimulating Hormone Testing? North American Menopause Society https://www.menopause.org/for-women/menopauseflashes/menopause-symptoms-and-treatments/how-do-i-know-i’m-in-menopause- Accessed: 07 May 2024
  10. Menopause: Diagnosis & Treatment – Diagnosis. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/menopause/diagnosis-treatment/drc-20353401″ Accessed: 07 May 2024
Topic Last Updated: 16 May 2024 – Topic Last Reviewed: 07 May 2024