“An effective and safe treatment, low-dose local estrogen
applied directly to the vagina relieves vaginal dryness
and discomfort with sexual activity”.1

Umbrella

What may the Vaginal and Vulval Treatment Options Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Vaginal Estrogen/Oestrogen Products
  • Vaginal Inserts
  • Vaginal and Vulval Lubricants/Moisturizers
  • Vaginal and Vulval Treatment Options

Vaginal and Vulval Treatment Options

What are some menopause vaginal and vulval or Genitourinary Syndrome of Menopause (GSM) treatment options?

On page one and two in Genitourinary Syndrome of Menopause: Treatment Options, published May 2025, the (United States) Menopause Society, (formerly the North American Menopause Society) elaborate on:

Vaginal and Vulval Treatment Options“There are many effective treatment options for GSM, including over-the-counter and prescription therapies. Therapies for less severe symptoms include nonhormone over-the-counter lubricants used as needed for sexual activity and moisturizers used regularly (several times per week) to maintain moisture. Prescription therapies include low-dose vaginal estrogens, vaginal dehydroepiandrosterone inserts, and oral ospemifene. Nonhormone lubricants and moisturizers can be used in combination with prescription therapies for more severe symptoms.

  • Nonhormone Remedies
    • Vaginal Lubricants…
    • Vaginal Moisturizers…
    • Regular Sexual Stimulation…
    • Expanding Your Views of Sexual Pleasure…
    • Vaginal Dilators…
    • Pelvic Floor Exercises…
  • Vaginal Hormone Therapy…
    • An effective and safe treatment, low-dose local estrogen applied directly to the vulva and vagina relieves vulvar and vaginal discomfort, irritation, dryness, or pain with sexual activity…
    • FDA-approved low-dose vaginal estrogen products…
    • Dehydroepiandrosterone (DHEA; Prasterone)
    • Low-dose vaginal estrogen or DHEA may be options for…
  • Systemic Estrogen Therapy
  • Other Therapies…
    • Ospemifene
    • Vaginal Laser Therapy…”.2

Vaginal Moisturizers and Vaginal Lubricants

What vaginal moisturizers and vaginal lubricants are available?

In Vaginal Atrophy: Diagnosis & Treatment – Treatment the (United States) Mayo Clinic elaborate on:

“To treat genitourinary syndrome of menopause, your doctor may first recommend over-the-counter treatment options, including:

  • “Vaginal moisturizers. Try a vaginal moisturizer (K-Y Liquibeads, Replens, Sliquid, others) to restore some moisture to your vaginal area. You may have to apply the moisturizer every few days. The effects of a moisturizer generally last a bit longer than those of a lubricant
  • Water-based lubricants. These lubricants (Astroglide, K-Y Jelly, Sliquid, others) are applied just before sexual activity and can reduce discomfort during intercourse. Choose products that don’t contain glycerin or warming properties because women who are sensitive to these substances may experience irritation. Avoid petroleum jelly or other petroleum-based products for lubrication if you’re also using condoms, because petroleum can break down latex condoms on contact”.3

Vaginal Estrogen

What is vaginal estrogen?

On page one in Deciding About Hormone Therapy Use, published February 2025, the Menopause Society explain:

Vaginal and Vulval Treatment Options
“If you are bothered only by vaginal dryness, you can use very low doses of estrogen placed directly into the vagina. These low doses generally do not raise blood estrogen levels above postmenopause levels and do not treat hot flashes. You do not need to take a progestogen when using only low doses of estrogen in the vagina”.6

In Vaginal Atrophy: Diagnosis & Treatment – Treatment the Mayo Clinic elaborate on:

  • “Topical Estrogen
    • Vaginal Estrogen Cream (Estrace, Premarin)…
    • Vaginal Estrogen Suppositories (Imvexxy)…
    • Vaginal Estrogen Ring (Estring, Femring)…
    • Vaginal Estrogen Tablet (Vagifem)…
  • Ospemifene (Osphena)…
  • Prasterone (Intrarosa)…
  • Systemic Estrogen Therapy…
  • Vaginal Dilators…
  • Topical Lidocaine…
  • If you’ve had breast cancer…”.7

Health Care Provider

What if I would like to make down there less bothersome?

If you would like to make down there less bothersome, it may be in your best interest to choose to talk to your health care provider about this.

In Vaginal Atrophy: Symptoms & Causes – Symptoms: When To See A Doctor the Mayo Clinic encourage us to:

“Make an appointment with your doctor if you have any unexplained vaginal spotting or bleeding, unusual discharge, burning, or soreness.

Also make an appointment to see your doctor if you experience painful intercourse that’s not resolved by using a vaginal moisturizer (K-Y Liquibeads, Replens, Sliquid, others) or water-based lubricant (Astroglide, K-Y Jelly, Sliquid, others)”.8

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Sources

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Sources

  1. Genitourinary Syndrome of Menopause: Treatment Options. 2025:1-2. Menopause Society https://menopause.org/wp-content/uploads/for-women/MenoNote-GSM.pdf Accessed: 26 August 2025
  2. Genitourinary Syndrome of Menopause: Treatment Options. 2025:1-2. Menopause Society https://menopause.org/wp-content/uploads/for-women/MenoNote-GSM.pdf Accessed: 26 August 2025
  3. Vaginal Atrophy: Diagnosis & Treatment – Treatment. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/diagnosis-treatment/drc-20352294 Accessed: 26 August 2025
  4. Deciding About Hormone Therapy Use. 2025:1. Menopause Society https://menopause.org/wp-content/uploads/default-document-library/MenoNote-Deciding-About-HT-2025.pdf Accessed: 26 August 2025
  5. Vaginal Atrophy: Diagnosis & Treatment – Treatment. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/diagnosis-treatment/drc-20352294 Accessed: 26 August 2025
  6. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published 10 June 2022:3-4. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 26 August 2025
  7. Vaginal Atrophy: Diagnosis & Treatment – Treatment. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/diagnosis-treatment/drc-20352294 Accessed: 26 August 2025
Topic Last Updated: 26 August 2025 – Topic Last Reviewed: 26 August 2025