“Hormone therapy is one of the most effective treatments
available for bothersome hot flashes and night sweats.
If hot flashes and night sweats are disrupting your…”.1

Umbrella
What may the Hormone Therapy and Hot Flushes Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Hot Flashes
  • Hot Flushes
  • Menopausal Hormone Therapy (MHT)

Hormone Therapies

What are hormone therapies?

DotS the definition of hormone therapies may vary. The North American Menopause Society’s (NAMS) definition is:

“Hormone therapies are the prescription drugs used most often to treat hot flashes and genitourinary syndrome of menopause (GSM), which includes vaginal dryness, after menopause”.2

Preparations

What are some hormone therapy (HT) preparations to relieve hot flushes?

On page one in Menopausal Hormone Therapy the European Menopause and Andropause Society explain:

“Various menopausal hormonal preparations are available. Different routes of administration can be used for individual hormones. The routes of administration for estrogen are oral, transdermal (patches, gels and spray), subcutaneous (implants) and vaginal. The availability of individual preparations varies worldwide”.3

Effective or Not

How effective is HT for the treatment of hot flushes?

On page one in Deciding About Hormone Therapy Use: Potential Benefits, published July 2022, the NAMS elaborate on:

Hormone Therapy and Hot Flushes “Hormone therapy is one of the most effective treatments available for bothersome hot flashes and night sweats. If hot flashes and night sweats are disrupting your daily activities and sleep, HT may improve sleep and fatigue, mood, ability to concentrate, and overall quality of life. Treatment of bothersome hot flashes and night sweats is the principal reason women use HT”.4

Potential Benefits

Do the potential benefits of HT outweigh the potential risks when taking HT for the treatment of hot flushes?

In Hot Flashes: Diagnosis & Treatment – Diagnosis: Treatment the (United States) Mayo Clinic note:

“The most effective way to relieve the discomfort of hot flashes is to take estrogen, but taking this hormone carries risks. If estrogen is appropriate for you and you start it within 10 years of your last menstrual period or before age 60, the benefits can be greater than the risks”.5

Potential Risks

What are the potential risks when taking HT for the treatment of hot flushes?

On page one in Deciding About Hormone Therapy Use: Potential Risks the NAMS explain:

“As with all medications, HT is associated with some potential risks. For healthy women with bothersome hot flashes aged younger than 60 years or within 10 years of menopause, the benefits of HT generally outweigh the risks. Hormone therapy might slightly increase your risk of stroke or blood clots in the legs or lungs (especially if taken in pill form)”.6

Health Care Provider

What if I choose to use HT for my hot flushes?

If you choose to use HT for your hot flushes, it may be in your best interest to also choose to talk to your health care provider about this.

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use. Discussions with women should also cover aspects such as when to consider stopping HRT and how this can be done (by gradually reducing the dose of HRT). No arbitrary limits should be set on age or duration of HRT intake”.7

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Sources

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Sources

  1. Deciding About Hormone Therapy Use: Potential Benefits. 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 02 December 2022
  2. Menopause FAQs: Hormone Therapy for Menopause Symptoms – Q. What Is Hormone Therapy? North American Menopause Society https://www.menopause.org/for-women/menopause-faqs-hormone-therapy-for-menopause-symptoms Accessed: 02 December 2022
  3. Menopausal Hormone Therapy. 2022: 1. European Menopause and Andropause Society https://emas-online.org/wp-content/uploads/2022/05/Menopausal-hormone-therapy.pdf Accessed: 02 December 2022
  4. Deciding About Hormone Therapy Use: Potential Benefits. 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 02 December 2022
  5. Hot Flashes: Diagnosis & Treatment – Diagnosis: Treatment. 20 May 2022. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/hot-flashes/diagnosis-treatment/drc-20352795 Accessed: 02 December 2022
  6. Deciding About Hormone Therapy Use: Potential Risks. 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 02 December 2022
  7. Hamoda, H, Mukherjee, A, Morris, E, Baldeweg, S. E., Jayasena, C. N., Briggs, P, Moger, S. Optimising the Menopause Transition: Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2 https://journals.sagepub.com/doi/10.1177/20533691221104882 Accessed: 02 December 2022
Topic Last Updated: 02 December 2022 – Topic Last Reviewed: 02 December 2022

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