“Hormone therapy is one of the most effective treatments
available for bothersome hot flashes and night sweats.
If hot flashes and night sweats are disrupting your…”.1

Umbrella

What may the Hormone Therapy and Hot Flushes Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Hot Flashes
  • Hot Flushes
  • Menopausal Hormone Therapy (MHT)

Hormone Therapies

What are hormone therapies?

DotS the definition of hormone therapies may vary. The Menopause Society’s (formerly the North American Menopause Society) definition is:

“Hormone therapies (HT), sometimes mistakenly called hormone replacement therapy, are the prescription drugs used most often to treat menopause symptoms such as hot flashes and genitourinary syndrome of menopause (GSM), which includes vaginal dryness after menopause”.2

Preparations

What are some hormone therapy (HT) preparations to relieve hot flushes?

On page one in Menopausal Hormone Therapy the European Menopause and Andropause Society explain:

“Various menopausal hormonal preparations are available. Different routes of administration can be used for individual hormones. The routes of administration for estrogen are oral, transdermal (patches, gels and spray), subcutaneous (implants) and vaginal. The availability of individual preparations varies worldwide”.3

Effective or Not

How effective is HT for the treatment of hot flushes?

On page one in Hormone Therapy, published September 2024, the Menopause Society elaborate on:

Hormone Therapy and Hot Flushes“Hormone therapy is FDA-approved as a first-line therapy for the relief of bothersome hot flashes and is shown to be the most effective treatment. In particular, the benefits particularly outweigh the risks for HT when used in early menopause to relieve vasomotor symptoms (VMS), hot flashes, night sweats, and sleep disturbances”.4

Potential Benefits

Do the potential benefits of HT outweigh the potential risks when taking HT for the treatment of hot flushes?

In Hot Flashes: Diagnosis & Treatment – Diagnosis: Treatment the (United States) Mayo Clinic note:

“The most effective way to relieve the discomfort of hot flashes is to take estrogen, but taking this hormone carries risks. If estrogen is appropriate for you and you start it within 10 years of your last menstrual period or before age 60, the benefits can be greater than the risks”.5

Potential Risks

What are the potential risks when taking HT for the treatment of hot flushes?

In Hormone Therapy: Is Hormone Therapy Safe? the Menopause Society explain:

“For most women, experts agree that HT helps to control moderate to severe menopause symptoms such as hot flashes and vaginal dryness within 10 years of menopause and up to age 59 years. Also, women should use the lowest dose for the shortest amount of time needed to keep the symptoms under control.

You and your healthcare professional need to balance your individual benefits and risks based on your medical history. For example, if you don’t have a uterus and can take ET alone, your risks are different from those women who still have a uterus and must use EPT to protect against uterine cancer”.6

What is ET?

ET can be an abbreviation for Estrogen Therapy.

What is EPT?

EPT can be an abbreviation for Estrogen Plus Progestogen Therapy.

Health Care Provider

What if I choose to use HT for my hot flushes?

If you choose to use HT for your hot flushes, it may be in your best interest to also choose to talk to your health care provider about this.

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use. Discussions with women should also cover aspects such as when to consider stopping HRT and how this can be done (by gradually reducing the dose of HRT). No arbitrary limits should be set on age or duration of HRT intake”.7

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Sources

  1. Deciding About Hormone Therapy Use: Potential Benefits. 2022:1. Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 29 September 2024
  2. Hormone Therapy. Menopause Society https://menopause.org/patient-education/menopause-topics/hormone-therapy Accessed: 29 September 2024
  3. Menopausal Hormone Therapy. 2022: 1. European Menopause and Andropause Society https://emas-online.org/wp-content/uploads/2022/05/Menopausal-hormone-therapy.pdf Accessed: 29 September 2024
  4. Hormone Therapy: What Is Hormone Therapy? 2024. Menopause Society https://menopause.org/patient-education/menopause-topics/hormone-therapy Accessed: 29 September 2024
  5. Hot Flashes: Diagnosis & Treatment – Diagnosis: Treatment. 12 December 2023. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/hot-flashes/diagnosis-treatment/drc-20352795 Accessed: 29 September 2024
  6. Hormone Therapy: Is Hormone Therapy Safe? Menopause Society https://menopause.org/patient-education/menopause-topics/hormone-therapy Accessed: 29 September 2024
  7. Hamoda, H, Mukherjee, A, Morris, E, Baldeweg, S. E., Jayasena, C. N., Briggs, P, Moger, S. Optimising the Menopause Transition: Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2 https://journals.sagepub.com/doi/10.1177/20533691221104882 Accessed: 29 September 2024
Topic Last Updated: 29 September 2024 – Topic Last Reviewed: 29 September 2024