“The benefits of hormone therapy outweigh the risks for
most healthy symptomatic women who are aged younger
than 60 years and within 10 years of menopause onset”.1

Umbrella

What may the Hormone Therapy Postmenopause Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT) After Menopause
  • Hormone Therapy (HT) After Menopause
  • Menopausal Hormone Therapy (MHT) After Menopause
  • Postmenopausal/Postmenopause Hormone Replacement Therapy (HRT)/Hormone Therapy (HT)

50 and 60 Years

What is the association between HT, age and time since menopause, for women between 50 and 60 years?

In Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Are the Risks of MHT? the (Australian) Jean Hailes for Women’s Health (JH) elaborate on:

“A recent comprehensive review of evidence on MHT found it is an effective and safe treatment for the relief of menopausal symptoms for healthy women. The data showed that MHT had low risks for women aged between 50 and 60 years, but more research is needed to understand how MHT might affect other women’s health issues”.2

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement, published 07 July 2022, the North American Menopause Society (NAMS) (now the Menopause Society) explain:

Hormone Therapy Postmenopause

  • “Risk stratification by age and time since menopause is recommended.
  • The benefits of hormone therapy outweigh the risks for most healthy symptomatic women who are aged younger than 60 years and within 10 years of menopause onset.
  • Transdermal routes of administration and lower doses of hormone therapy may decrease risk of venous thromboembolism and stroke”.3

Older Than 60 Years

What is the association between HT and being older than 60 years?

In Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Are the Risks of MHT? the JH note:

“It is not recommended you start MHT if you are older than 60 years or if you’ve been postmenopausal for 10 years or more”.4

Postmenopausal 10 Years and 10 Years+

What is the association between HT and being postmenopausal for 10 years or more?

In Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Are the Risks of MHT? the JH note:

“It is not recommended you start MHT if you are older than 60 years or if you’ve been postmenopausal for 10 years or more”.5

Bone Health

Does HT have an effective role in the prevention and treatment of osteoporosis?

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “In addition, HRT has been shown to have an effective role in the prevention and treatment of osteoporosis. Bisphosphonates are considered as first-line options for most patients with postmenopausal osteoporosis due to their broad spectrum of anti-fracture efficacy. HRT may be considered as an additional alternative option, particularly in younger postmenopausal women with menopausal symptoms who are at increased risk of fractures”.6

Heart Health

Does HT have an effective role for health health?

On page one in Deciding About Hormone Therapy Use: Potential Risks the NAMS note:

“Some studies suggest that HT might be good for your heart if you start before age 60 or within 10 years of menopause. However, if you start HT further from menopause or after age 60, HT might slightly increase your risk of heart disease. Although there are risks associated with taking HT, they are not common, and most go away after you stop treatment”.7

Chronic Disease Prevention

Should HT be used for chronic disease prevention?

On page four in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause one of the recommendations is:

  • “HRT should not be recommended for the primary or secondary prevention of chronic disease in women experiencing the menopause in keeping with national and international guidelines”.8

Stop

Does HT need to be routinely stopped?

In Menopause Management Options: Menopausal Hormone Therapy (MHT) – How Long Do You Need To Take MHT? the JH elaborate on:

“You can take MHT at low doses for as long as you need. Many women have symptoms for around eight years and one in four women have symptoms into their 60s and 70s. The benefits of MHT far outweigh the risks in healthy women within 10 years of reaching menopause”.9

On page one in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement the NAMS note:

  • “Hormone therapy does not need to be routinely discontinued in women aged older than 60 or 65 years and can be considered for continuation beyond age 65 for persistent VMS, quality-of-life issues, or prevention of osteoporosis after appropriate evaluation and counseling of benefits and risks”.10

On page six of Menopause and Menopause Hormone Therapy: 3. When Should MHT Be Started and Stopped? Long-Term Use, the International Menopause Society’s (IMS) Leaflet for Women, for World Menopause Day 2024 the IMS note11:

Hormone therapy Postmenopause

Fountain of Youth

Is HT the “fountain of youth”?

On page three of Menopause and Menopause Hormone Therapy: 1. Who Is MHT For? Who Might Not Need MHT? the IMS explain:

“Women who go through menopause at the natural age (after 45) and have no bothersome symptoms usually don’t need MHT. Some people believe MHT is a “fountain of youth”, but there’s little scientific evidence for that. It’s important to remember MHT is not recommended solely to prevent aging, memory loss, or dementia”.12
Hormone Therapy Postmenopause

Health Care Provider

What if I am postmenopausal and choose to use HT?

If you are postmenopausal and choose to use HT, it may be in your best interest to also choose to talk to your health care provider about this.

In Deciding About Hormone Therapy Use the NAMS elaborate on:

“Every woman is different, and you will decide about whether to use HT based on the severity of your symptoms, your personal and family health history, and your own beliefs about menopause treatments. Your healthcare professional will be able to help you with your decision”.13

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Sources

  1. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://menopause.org/wp-content/uploads/press-release/ht-position-statement-release.pdf Accessed: 25 March 2025
  2. Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Are the Risks of MHT? Last Updated: 03 December 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 25 March 2025
  3. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:1. North American Menopause Society https://menopause.org/wp-content/uploads/press-release/ht-position-statement-release.pdf Accessed: 25 March 2025
  4. Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Are the Risks of MHT? Last Updated: 03 December 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 25 March 2025
  5. Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Are the Risks of MHT? Last Updated: 03 December 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 25 March 2025
  6. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:3-4. https://journals.sagepub.com/doi/10.1177/20533691221104882 Accessed: 25 March 2025
  7. Deciding About Hormone Therapy Use: Potential Benefits. 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 25 March 2025
  8. Menopause and Menopause Hormone Therapy: 1. Who Is MHT For? Who Might Not Need MHT? 2024:3. International Menopause Society https://www.imsociety.org/wp-content/uploads/2024/10/2024-WMD-Leaflet_English.pdf Accessed: 25 March 2025
  9. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:4. https://journals.sagepub.com/doi/10.1177/20533691221104882 Accessed: 25 March 2025
  10. Menopause Management Options: Menopausal Hormone Therapy (MHT) – How Long Do You Need To Take MHT? Last Updated: 03 December 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 25 March 2025
  11. Menopause and Menopause Hormone Therapy: 3. When Should MHT Be Started and Stopped? Long-Term Use. 2024:3. International Menopause Society https://www.imsociety.org/wp-content/uploads/2024/10/2024-WMD-Leaflet_English.pdf Accessed: 25 March 2025
  12. The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement. 07 July 2022:2. North American Menopause Society https://menopause.org/wp-content/uploads/press-release/ht-position-statement-release.pdf Accessed: 25 March 2025
  13. Deciding About Hormone Therapy Use. 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 25 March 2025
Topic Last Updated: 25 March 2025 – Topic Last Reviewed: 25 March 2025