“Get regular follow-up care. See your healthcare
professional regularly to make sure the benefits of
menopause hormone therapy continue to outweigh…”.1

Umbrella

What may the Hormone Therapy Follow Up Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Hormone Replacement Therapy (HRT) Follow Up/Review
  • Hormone Therapy (HT) Follow Up/Review
  • Menopausal Hormone Therapy (MHT) Follow Up/Review

Initial Follow Up

Initially, if menopausal women choose to use hormone therapy (HT), how often should they follow up?

In Menopause: Treatment – Follow-Up Appointments according to the (United Kingdom) NHS:

Hormone Therapy Follow Up

“If you’re having treatment for your symptoms of menopause or perimenopause, you’ll need to return to the doctor or nurse who is prescribing your HRT for a follow-up review after 3 months.

When you and your doctor or nurse agree your treatment is working well for you, you’ll need to see them once a year”.2

In The 2023 Practitioner’s Toolkit for Managing Menopause: Management – Effectiveness: Managing Clinical Side Effects of MHT Therapy, published online 30 October 2023, the authors explain:

“Optimally, women using systemic MHT should have a medical review at 3 months to assess symptom relief and side effects. This is also an opportunity to discuss any patient concerns and ensure correct use of the prescribed therapy. Further follow-up will be determined by whether any treatment adjustments are made or investigations initiated. Long-term follow-up should be at least yearly”.3

Regular Follow Up

If menopausal women choose to use hormone therapy (HT), when is regular follow up required?

On page five of Menopause and Menopause Hormone Therapy: 3. When Should MHT Be Started and Stopped? When To Stop the International Menopause Society’s (IMS) Leaflet for Women for World Menopause Day 2024, the IMS note:

  • “It’s important to regularly check with your healthcare professional to see if continuing MHT is the right choice for you”.4

The (United Kingdom) Women’s Health Concern note:

“Women on HRT should be re-assessed by their doctor at least annually”.5

In the Hormone Therapy: Is It Right for You: Who Can Benefit From Hormone Therapy? the (United States) Mayo Clinic also note:

  • “Get regular follow-up care. See your healthcare professional regularly to make sure the benefits of menopause hormone therapy continue to outweigh the risks. You also should continue to have regular screenings, such as mammograms, blood pressure measurement and cervical cancer screening”.6

Follow-Up Format

What may the follow-up include?

In The 2023 Practitioner’s Toolkit for Managing Menopause: Management – Effectiveness: Managing Clinical Side Effects of MHT Therapy, the authors also note:

“Review should include updating medical history and a general medical examination and breast assessment as indicated. Investigations should be individually determined, with mammography frequency according to local recommendations”.7

In Menopause: Treatment – Follow-Up Appointments the NHS explain:

“During your reviews, your doctor or nurse may:

  • Make sure your symptoms are under control
  • Ask about any side effects and vaginal bleeding
  • Check your weight and blood pressure
  • Review the type of HRT you’re taking and make any necessary changes”.8

Unscheduled or Prolonged Bleeding

What may unscheduled or prolonged bleeding require?

In The 2023 Practitioner’s Toolkit for Managing Menopause: Management – Effectiveness: Managing Clinical Side Effects of MHT Therapy, the authors explain:

“Unscheduled or prolonged bleeding 3–6 months after commencing MHT needs investigation (ultrasound and/or biopsy), and where indicated, specialist referral. The need for ongoing MHT, the formulation and dose requirement should be reviewed”.9

Health Care Provider

How long can I take HT or menopausal hormone therapy (MHT)?

In Menopause Management Options: Menopausal Hormone Therapy (MHT) – How Long Do You Need To Take MHT? the JH note:

“You can take MHT at low doses for as long as you need. Many women have symptoms for around 8 years and one in 4 women have symptoms into their 60s and 70s.

When using MHT in midlife:

  • Start low
  • Go slow
  • Review often”.10


The NHS explain:

“You can choose to continue taking HRT. The doctor or nurse prescribing your HRT can discuss with you the benefits and risks, so you can decide what’s right for you.

You can take HRT for as long as you need it. You can discuss this with your doctor or nurse at your yearly review”.11

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Sources

  1. Hormone Therapy: Is It Right for You? 15 April 2025. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/menopause/in-depth/hormone-therapy/art-20046372 Accessed: 01 May 2025
  2. Menopause: Treatment – Follow-Up Appointments. Page Last Reviewed: 17 May 2022. NHS https://www.nhs.uk/conditions/menopause/treatment/ Accessed: 01 May 2025
  3. Davis, S. R., Taylor, S., Hemachandra, C., Magraith, K., Ebeling, P. R., Jane, F., and Islam, R. M. The 2023 Practitioner’s Toolkit for Managing Menopause: Management – – Effectiveness: Managing Clinical Side Effects of MHT Therapy. First Published Online: 30 October 2023 https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783 Accessed: 01 May 2025
  4. Menopause and Menopause Hormone Therapy: 3. When Should MHT Be Started and Stopped? When To Stop. 2024:5. International Menopause Society https://www.imsociety.org/wp-content/uploads/2024/10/2024-WMD-Leaflet_English.pdf Accessed: 01 May 2025
  5. HRT Benefits and Risks: In Summary. Updated: November 2020. Women’s Health Concern https://www.womens-health-concern.org/help-and-advice/factsheets/hrt-know-benefits-risks/ Accessed: 01 May 2025
  6. Hormone Therapy: Is It Right for You? 15 April 2025. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/menopause/in-depth/hormone-therapy/art-20046372 Accessed: 01 May 2025
  7. Davis, S. R., Taylor, S., Hemachandra, C., Magraith, K., Ebeling, P. R., Jane, F., and Islam, R. M. The 2023 Practitioner’s Toolkit for Managing Menopause: Management – – Effectiveness: Managing Clinical Side Effects of MHT Therapy. First Published Online: 30 October 2023 https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783 Accessed: 01 May 2025
  8. Menopause: Treatment – Follow-Up Appointments. Page Last Reviewed: 17 May 2022. NHS https://www.nhs.uk/conditions/menopause/treatment/ Accessed: 01 May 2025
  9. Davis, S. R., Taylor, S., Hemachandra, C., Magraith, K., Ebeling, P. R., Jane, F., and Islam, R. M. The 2023 Practitioner’s Toolkit for Managing Menopause: Management – – Effectiveness: Managing Clinical Side Effects of MHT Therapy. First Published Online: 30 October 2023 https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783 Accessed: 01 May 2025
  10. Treatments for Menopause: Menopausal Hormone Therapy (MHT) – How Long Do You Need To Take MHT? Last Updated: 24 April 2025 | Last Reviewed: 22 April 2025. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 01 May 2025
  11. Menopause: Treatment – Follow-Up Appointments. Page Last Reviewed: 17 May 2022. NHS https://www.nhs.uk/conditions/menopause/treatment/ Accessed: 01 May 2025
Topic Last Updated: 01 May 2025 – Topic Last Reviewed: 01 May 2025