“Currently, there is no routine, simple screening test to accurately detect ovarian cancer. Contrary to popular belief, cervical screening (i.e.: Pap smear) will not detect…”.1

Umbrella

What may the Ovarian Cancer Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Cancer of the Ovary
  • Ovarian Cancer

Cancer

What is cancer?

DotS the definition of cancer may vary. The (United States) National Cancer Institute’s (NCI) definition is:

Cancer
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems”.2

Ovarian Cancer

What is ovarian cancer?

DotS the definition of ovarian cancer may vary. The (United States) Centers for Disease Control and Prevention’s definition is:

“Ovarian cancer is a group of diseases that originates in the ovaries, or in the related areas of the fallopian tubes and the peritoneum”.3

Types

What are the different types of ovarian cancer?

In Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening (PDQ®)–Patient Version the NCI elaborate the different types of ovarian cancer and include a diagram of the ovaries.

Symptoms

What are the symptoms of ovarian cancer?

In Symptoms of Ovarian Cancer: What Are the Symptoms? the [United Kingdom] Target Ovarian Cancer elaborate on:

Ovarian Cancer

  • “Persistent bloating (not bloating that comes and goes)
  • Feeling full quickly and/or loss of appetite
  • Pelvic or abdominal pain (that’s from your tummy to the top of your thighs)
  • Urinary symptoms (needing to wee more urgently or more often than usual)”.4

Ovarian Cancer

 

Ovarian Cancer

 

 

 

 

 

 

 

 

 

Other Symptoms

What can be other symptoms of ovarian cancer?

In Symptoms of Ovarian Cancer: What Are the Symptoms? Target Ovarian Cancer also explain:

“Occasionally there can be other symptoms:

  • Changes in bowel habit (e.g. diarrhoea or constipation)
  • Extreme fatigue (feeling very tired)
  • Unplanned weight loss
  • Any unusual bleeding from the vagina before or after the menopause should always be investigated by a GP”.5

In Symptoms of Ovarian Cancer: What Are the Symptoms? Target Ovarian Cancer note:

“Symptoms will be:

  • New – they’re not normal for you
  • Frequent – they usually happen more than 12 times a month
  • Persistent – they don’t go away”.6

Cause

What causes ovarian cancer?

In Ovarian Cancer: Main Causes of Ovarian Cancer the (United Kingdom) NHS explain:

“You may have a higher chance of getting ovarian cancer if you:

  • Inherited a faulty gene, such as the BRCA genes or those linked to Lynch syndrome
  • Had breast cancer or bowel cancer
  • Had radiotherapy treatment for a previous cancer
  • Have endometriosis or diabetes
  • Started your periods at a young age or went through the menopause late (over 55), or have not had a baby – because these things may mean you’ve released more eggs (ovulated more)
  • Have never used any hormonal contraception, such as the pill or an implant
  • Are taking hormone replacement therapy (HRT)
  • Are overweight
  • Smoke”.7

Age

Is there an association between the risk of developing ovarian cancer and getting older?

In Ovarian Cancer Symptoms & Risks: What Are the Risk Factors for Ovarian Cancer? the World Ovarian Cancer Coalition explain:

Age
Your risk increase as you get older. Ovarian Cancer is more common in those aged 50-79. However, you can develop it when you are younger”.8

In Ovarian Cancer Risk: Age the Target Ovarian Cancer note:

“As with most cancers the risk of developing ovarian cancer increases as you get older. Those over the age of 50 have a higher risk. Most cases of ovarian cancer happen in those who have already gone through the menopause (when you stop having periods). More than 50 in 100 cases of ovarian cancer are in those over 65 years.

Although it’s not common, if you’re younger and haven’t been through the menopause you can get ovarian cancer. Over 1,000 women under the age of 50 develop ovarian cancer every year. That’s why it’s important that everyone is aware of the symptoms of ovarian cancer. This is especially important if you have a family history of ovarian or breast cancer”.9

Common or Not

How common is ovarian cancer?

In the United States, the NCI in Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening (PDQ®)–Patient Version: General Information About Ovarian, Fallopian Tube, and Primary Peritoneal Cancer elaborate on:

“In the United States, ovarian cancer is the fifth leading cause of cancer death in women.

While ovarian cancer is rare, it is the leading cause of death from cancer of the female reproductive system”.10

In the United Kingdom (UK) Cancer Research UK note:

“Around 7,500 women are diagnosed with ovarian cancer in the UK each year. This makes ovarian cancer the 6th most common cancer in women”.11

Pap Test

Does the Pap test check for ovarian cancer?

No. In Ovarian Cancer Testing & Detection the World Ovarian Cancer Coalition note:

“Currently, there is no routine, simple screening test to accurately detect ovarian cancer. Contrary to popular belief, cervical screening (i.e.: Pap smear) will not detect ovarian cancer. While cervical screening is effective in early detection of cervical cancer, it is not a test for ovarian cancer”.12

Ovarian Cancer

Symptom Diary

Where may I find an ovarian cancer symptom diary?

Your Country may have Links similar to:

Health Care Provider

What if I am worried about some symptoms I am experiencing?

In Symptoms of Ovarian Cancer: Worried About Your Symptom? Target Ovarian Cancer elaborate on:

“If you regularly experience any one or more of these symptoms, which aren’t normal for you, it’s important that you contact your GP. It’s unlikely that your symptoms are caused by a serious problem but it’s important to get checked out, even if they’re mild. Your GP should order a CA125 blood test. They may also order ultrasound scans of your ovaries and tummy.

If two or more of your close relatives have had cancer you should tell your GP as ovarian cancer can run in families”.“If you experience some of the symptoms of ovarian cancer for more than two weeks, talk to your doctor”.13

Who is a GP?

DotS and DotC (Depending on the Country) a GP may be a qualified and registered general practitioner, a medical practitioner, a medical doctor or a doctor.

Health Topics A-Z

Where may I find Health Topics A-Z related to Ovarian Cancer?

In Health Topics A-Z you may find:

Links

Where may I find Links related to Ovarian Cancer?

Your Country may have Links similar to:

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Ovarian Cancer Testing & Detection. World Cancer Coalition https://worldovariancancercoalition.org/about-ovarian-cancer/detection-testing/ Accessed: 01 September 2024
  2. Cancer. National Cancer Institute https://www.cancer.gov/publications/dictionaries/cancer-terms/def/cancer Accessed: 01 September 2024
  3. Ovarian Cancer: Ovarian Cancer Basics – What It Is. 12 September 2024. Centers for Disease Control and Prevention https://www.cdc.gov/ovarian-cancer/about/ Accessed: 01 September 2024
  4. Symptoms of Ovarian Cancer: What Are the Symptoms? Last Reviewed: November 2022. Target Ovarian Cancer https://targetovariancancer.org.uk/about-ovarian-cancer/symptoms Accessed: 01 September 2024
  5. Symptoms of Ovarian Cancer: What Are the Symptoms? Last Reviewed: November 2022. Target Ovarian Cancer https://targetovariancancer.org.uk/about-ovarian-cancer/symptoms Accessed: 01 September 2024
  6. Symptoms of Ovarian Cancer: What Are the Symptoms? Last Reviewed: November 2022. Target Ovarian Cancer https://targetovariancancer.org.uk/about-ovarian-cancer/symptoms Accessed: 01 September 2024
  7. Ovarian Cancer: Main Causes of Ovarian Cancer. Page Last Reviewed: 24 January 2022. NHS https://www.nhs.uk/conditions/ovarian-cancer/causes/ Accessed: 01 September 2024
  8. Ovarian Cancer Symptoms & Risks: What Are the Risk Factors for Ovarian Cancer? World Ovarian Cancer Coalition https://worldovariancancercoalition.org/about-ovarian-cancer/symptoms-risk-factors/ovarian-cancer-symptoms/ Accessed: 01 September 2024
  9. Ovarian Cancer Risk: Age. Last Reviewed: April 2023. Target Ovarian Cancer https://targetovariancancer.org.uk/about-ovarian-cancer/risk Accessed: 01 September 2024
  10. Ovarian, Fallopian Tube, and Primary Peritoneal Cancer Screening (PDQ®)–Patient Version: General Information About Ovarian, Fallopian Tube, and Primary Peritoneal Cancer. Updated: 31 March 2023. National Cancer Institute https://www.cancer.gov/types/ovarian/patient/ovarian-screening-pdq#section/_5 Accessed: 01 September 2024
  11. Ovarian Cancer: How Common It Is. Last Reviewed: 30 November 2021. Cancer Research UK https://about-cancer.cancerresearchuk.org/about-cancer/ovarian-cancer/what-is-ovarian-cancer Accessed: 01 September 2024
  12. Ovarian Cancer Testing & Detection. World Cancer Coalition https://worldovariancancercoalition.org/about-ovarian-cancer/detection-testing/ Accessed: 01 September 2024
  13. Ovarian Cancer: Diagnosis. Last Updated: 07 December 2023 | Last Reviewed: 14 April 2023. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/vulva-vagina-ovaries-uterus/ovarian-cancer#diagnosis Accessed: 01 September 2024
Topic Last Updated: 20 September 2024 – Topic Last Reviewed: 01 September 2024

“Most uterine cancers are found in women who are going through or who have gone through menopause—the time of life when your menstrual periods stop”.1

Umbrella

What may the Uterine Cancer Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Cancer of the Uterus
  • Endometrial Cancer
  • Sarcoma of the Uterus
  • Uterine Cancer
  • Uterus Cancer
  • Womb Cancer

Uterus

What is the uterus?

DotS the definition of uterus may vary. The (United States) Centers for Disease Control and Prevention’s (CDC) definition is:

“The uterus is the pear-shaped organ in a woman’s pelvis (between the hip bones). The uterus, also called the womb, is where the baby grows when a woman is pregnant”.2

Uterine Cancer

What is uterine cancer?

DotS the definition of uterine cancer may vary. In Uterine Cancer: Types of Uterine Cancer the International Gynecologic Cancer Society’s (IGCS) definition is:

“Uterine cancer is a disease in which cancer cells form in the tissues of the uterus, also known as the womb.

There are two primary types of uterine cancer:

  • Endometrial cancer, which is the most common form of uterine cancer. Endometrial cancer begins in the inner lining of the womb, known as the endometrium
  • Uterine sarcoma forms in the muscles and supporting tissues of the uterus. It is rare in comparison to other uterine cancers”.3

Uterine Cancer

Signs and Symptoms

What may be signs and symptoms of endometrial cancer?

In Uterine Cancer: Signs and Symptoms the IGCS explain:

“These are the most common signs and symptoms of uterine/endometrial cancer. If you experience any of these signs, always talk to your doctor, especially if you have the risk factors.

  • Vaginal bleeding after menopause
  • Bleeding between periods
  • An abnormal watery or blood-tinged vaginal discharge
  • Pelvic pain or pressure”.4

Uterine Cancer

Cause

What causes the most common type of uterine cancer, endometrial cancer?

In Womb Cancer: Risks and Cause of Womb Cancer the (United Kingdom) Cancer Research UK elaborate on:

“Being overweight or obese is one of the biggest risks of womb cancer in the UK. There are some other risk factors that can increase your risk of developing womb cancer”.5

Risk Factors

What are risk factors for uterine cancer?

In Uterine Cancer: Uterine Cancer Risk Factors – Conditions That Can Increase Risk Factors the CDC explain:

“There is no way to know for sure if you will get uterine cancer. Some women get it without being at high risk. However, several factors may increase the chance that you will get uterine cancer, including if you:

  • Are older than 50
  • Have obesity
  • Take estrogen by itself (without progesterone) for hormone replacement during menopause
  • Have had trouble getting pregnant, or have had fewer than five periods in a year before starting menopause
  • Take tamoxifen, a drug used to prevent and treat certain types of breast cancer
  • Have close family members who have had uterine, colon, or ovarian cancer.

If one or more of these things is true for you, it does not mean you will get uterine cancer. But you should speak with your doctor to see if he or she recommends more frequent exams”.6

Age

Is there an association between age and uterine cancer?

In Uterine Cancer: Fast Facts the IGCS note:

  • “Uterine cancer most frequently occurs in women over the age of 45, though it can affect younger women”.7

Menopause

Is there an association between menopause and uterine cancer?

In Uterine Cancer: Uterine Cancer Basics – Types the CDC note:

Menopause“All women are at risk for uterine cancer as long as they have a uterus, and the risk increases with age. Most uterine cancers are found in women who are going through or who have gone through menopause—the time of life when your menstrual periods stop”.8

In Womb (Uterus) Cancer: Causes – Who Is More Likely To Get Womb Cancer the (United Kingdom) NHS elaborate on:

“Womb cancer is most common in women who’ve been through menopause. It can affect anyone with a womb.

You cannot get womb cancer if you’ve had surgery to remove your womb (hysterectomy)”.9

The American Cancer Society (ACS) note:

“The American Cancer Society recommends that at the time of menopause, all women should be told about the risks and symptoms of endometrial cancer. They should report any unusual vaginal bleeding or spotting to a health care provider”.10

High-Income Countries

Is there an association between high-income countries and uterine cancer?

In Uterine Cancer Awareness: June Is Uterine Cancer Awareness Month the IGCS elaborate on:

“Uterine cancer is the most common gynecologic cancer among women residing in high-income countries.

And unlike many other cancers, the incidence and death rates are rising.

The number of deaths from this disease has been increasing by almost 2 percent each year, with even sharper spikes among Asian, Hispanic, and Black women in the United States”.11
Uterine Cancer

Pap Test

Does the Pap test screen for uterine cancer?

No. According to the CDC:

“There are no screening tests for uterine cancer in women who do not have any signs or symptoms. The Pap test does not screen for uterine cancer”.12

Does the Pap test screen for endometrial cancer?

No. The ACS note:

“There are no screening tests for uterine cancer in women who do not have any signs or symptoms. The Pap test does not screen for uterine cancer”.13

Health Care Provider

What if I think I have uterine cancer?

If you think you have uterine cancer, it may be in your best interest to choose to talk to your health care provider about this. The (United States) Mayo Clinic explain:

“See your healthcare professional as soon as you can if you bleed from your vagina after menopause”.14

In Womb (Uterus) Cancer: Overview – Get Your Symptoms Checked the NHS note:

“It’s important to get any symptoms of womb cancer checked as soon as possible. Finding it earlier makes it easier to treat”.15

Cancer Australia explain:

“If you have been told you have ‘cancer of the uterus’, ‘cancer of the womb’ or ‘uterine cancer’, and you are not sure if it is endometrial cancer or uterine sarcoma, check with your doctor”.16

The CDC also note:

“If your doctor says that you have uterine cancer, ask to be referred to a gynecologic oncologist—a doctor who has been trained to treat gynecologic cancers, including uterine cancer. This doctor will work with you to create a treatment plan”.17

Health Topics A-Z

Where may I find Health Topics A-Z related to Uterine Cancer?

In Health Topics A-Z you may find:

Links

Where may I find Links related to Uterine Cancer?

Your country may have Links similar to:

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Uterine Cancer: Uterine Cancer Basics – Types. 09 September 2024. Centers for Disease Control and Prevention https://www.cdc.gov/uterine-cancer/about/ Accessed: 18 September 2024
  2. Uterine Cancer: Uterine Cancer Basics – What It Is. 09 September 2024. Centers for Disease Control and Prevention https://www.cdc.gov/uterine-cancer/about/ Accessed: 18 September 2024
  3. Uterine Cancer: Types of Uterine Cancer. International Gynecologic Cancer Society https://igcs.org/uterine/#el-e695d19b Accessed: 18 September 2024
  4. Uterine Cancer: Signs and Symptoms. International Gynecologic Cancer Society https://igcs.org/uterine/#el-fe32cc10 Accessed: 18 September 2024
  5. Womb Cancer: Risks and Cause of Womb Cancer. Last Reviewed: 22 February 2024. Cancer Research UK https://about-cancer.cancerresearchuk.org/about-cancer/womb-cancer/risks-causes Accessed: 18 September 2024
  6. Uterine Cancer: Uterine Cancer Risk Factors – Conditions That Can Increase Risk. 09 September 2024. Centers for Disease Control and Prevention https://www.cdc.gov/uterine-cancer/risk-factors/ Accessed: 18 September 2024
  7. Uterine Cancer: Fast Facts. International Gynecologic Cancer Society https://igcs.org/uterine/ Accessed: 18 September 2024
  8. Uterine Cancer: Uterine Cancer Basics – Types. 09 September 2024. Centers for Disease Control and Prevention https://www.cdc.gov/uterine-cancer/about/ Accessed: 18 September 2024
  9. Womb (Uterus) Cancer: Causes – Who Is More Likely To Get Womb Cancer. Page Last Reviewed: 21 October 2021. NHS https://www.nhs.uk/conditions/womb-cancer/causes/ Accessed: 18 September 2024
  10. Cancer Facts for Women: Endometrial Cancer. Last Revised: 31 October 2023. American Cancer Society https://www.cancer.org/healthy/findcancerearly/womenshealth/cancer-facts-for-women Accessed: 18 September 2024
  11. Uterine Cancer Awareness: June Is Uterine Cancer Awareness Month. International Gynecologic Cancer Society https://igcs.org/uterine-cancer-awareness/ Accessed: 18 September 2024
  12. Uterine Cancer: Screening for Uterine Cancer – What To Know. 09 September 2024. Centers for Disease Control and Prevention https://www.cdc.gov/uterine-cancer/screening/ Accessed: 18 September 2024
  13. Cancer Facts for Women: Endometrial Cancer – What You Can Do: Know Your Risk and the Signs. Last Revised: 31 October 2023. American Cancer Society https://www.cancer.org/healthy/findcancerearly/womenshealth/cancer-facts-for-women Accessed: 18 September 2024
  14. Menopause: Symptoms & Causes – Symptoms: When To See A Doctor. 07 August 2024. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/menopause/symptoms-causes/syc-20353397 Accessed: 18 September 2024
  15. Womb (Uterus) Cancer: Overview – Get Your Symptoms Checked. Page Last Reviewed: 21 October 2021. NHS https://www.nhs.uk/conditions/womb-cancer/#when-to-see-a-gp Accessed: 18 September 2024
  16. Endometrial Cancer: What Is Endometrial Cancer? Cancer Australia https://canceraustralia.gov.au/affected-cancer/cancer-types/gynaecological-cancers/endometrial-cancer Accessed: 18 September 2024
  17. Uterine Cancer: Treatment of Uterine Cancer – How Is Uterine Cancer Treated? 09 September 2024. Centers for Disease Control and Prevention https://www.cdc.gov/uterine-cancer/treatment/ Accessed: 18 September 2024
Topic Last Updated: 18 September 2024 – Topic Last Reviewed: 18 September 2024

“Most women become menopausal naturally
between the ages of 45 and 55 years,
with the average age of onset at around 51 years”.1

Umbrella

What may the Menopause Evidence-Based Information Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Early Menopause
  • Induced Menopause
  • Menopause
  • Perimenopause
  • Premature Menopause
  • Surgical Menopause

Menopause

What is menopause?

DotS the definition of menopause may vary. In Menopause: How Menopause Occurs, dated 17 October 2022, the World Health Organization’s definition is:

“Natural menopause is deemed to have occurred after 12 consecutive months without menstruation for which there is no other obvious physiological or pathological cause and in the absence of clinical intervention”.2

Menopause Age

What is the average age of menopause?

In What Is Menopause? Definition of Menopause the Australasian Menopause Society explain:

“Most women become menopausal naturally between the ages of 45 and 55 years, with the average age of onset at around 51 years. Surgical menopause refers to menopause as a result of bilateral oophorectomy. Premature menopause or premature ovarian insufficiency may occur before the age of 40 due to natural ovarian function ceasing, following surgery to remove the ovaries, or as a result of chemo/ radiotherapy. Menopause is considered “early” when it occurs between 40 and 45 years”.3

Menopause Symptoms

What are some menopause symptoms?

In Symptoms of Menopause: Physical and Emotional Symptoms the (Australian) Jean Hailes for Women’s Health (JH) elaborate on:

“Physical Symptoms

Physical symptoms may include:

  • Irregular periods
  • Hot Flushes
  • Night sweats
  • Sleep problems
  • Sore breasts
  • Itchy, crawly or dry skin
  • Menopause Evidence-Based InformationExhaustion and fatigue
  • Dry vagina
  • Loss of sex drive (libido)
  • Headaches or migraines
  • More pronounced premenstrual syndrome (PMS)
  • Aches and pains
  • Bloating
  • Urinary problems
  • Weight gain due to a slower metabolism


Psychological and Emotional Symptoms

Psychological and emotional symptoms may include:

  • Feeling irritable or frustrated
  • Feeling anxious
  • Difficulty concentrating
  • Brain fog
  • Forgetfulness
  • Lowered mood
  • Mood swings
  • Feeling you can’t cope as well as you used to”.4

Menopause Symptoms Duration

What is the average duration of menopause symptoms?

On page one and two in Optimising the Menopause Transition: Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, the authors note:

“It is estimated that menopausal symptoms affect more than 75% of women, with over 25% of women describing severe symptoms. Furthermore, menopausal symptoms may last for a long time with an average duration of 7 years, with a third of women experiencing symptoms beyond 7 years”.5

Healthy Lifestyle

Can a healthy lifestyle improve menopause symptoms?

In the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “Women should be advised that implementing or maintaining a healthy lifestyle can improve menopause symptoms. A healthy diet (one low in saturated fat and salt and rich in calcium and vitamin D), stopping smoking, reducing alcohol intake and including regular exercise can be beneficial. Reducing caffeine intake may also improve symptoms”.6

Treatments

What treatments are available?

On page one in Emotional Wellness In Menopause: What Treatments Are Available? the (British) Women’s Health Concern elaborate on:

“There is no one size fits all for women when it comes to managing physical or psychological symptoms of menopause, but a variety of treatments are available.

  • Anti-depressants can help with emotional and cognitive symptoms of the menopause. However, unless you have been diagnosed with depression, there are other treatments which may be more helpful and appropriate
  • Hormone Replacement Therapy (HRT) can help with many cognitive and emotional symptoms of menopause. HRT can also help improve quality of sleep. It’s useful to keep a record of symptoms to discuss with your HRT prescriber as this will help identify the best HRT regime for you
  • Cognitive Behavioural Therapy (CBT) and other talking therapies can be hugely beneficial in dealing with some of the emotional symptoms of menopause. Even women who have never used therapies before and them helpful to navigate their menopause journey
  • Mindfulness and meditation are popular techniques to help relax and clear the mind – a very useful addition to managing some of the emotional and cognitive symptoms of menopause. Alongside restorative exercise such as yoga and Pilates, both body and mind can recover and heal”.7

Health Care Provider

What if I would like help with my menopause?

If you would like help with your menopause, it may be in your best interest to choose to talk to your health care provider about this.

In What Is Menopause? When To See Your Doctor the JH explain:

“Talk to your doctor if you are worried about:

  • Irregular periods
  • Heavy bleeding
  • Bleeding after menopause
  • Increased premenstrual syndrome (PMS) symptoms
  • Menopausal symptoms, such as hot flushes, that interfere with your daily life”.8

In Menopause: Diagnosis & Treatment – Treatment the (United States) Mayo Clinic encourage us to seek help:

“Before deciding on any form of treatment, talk with your healthcare professional about your choices and the risks and benefits of each. Review your choices yearly. Your needs and the treatment choices may change”.9

Health Topics A-Z

Where may I find Health Topics A-Z related to Menopause Evidence-Based Information?

In Health Topics A-Z you may find:

Links

Where may I find Links related to Menopause Evidence-Based Information?

Your Country may have Links similar to:

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. What Is Menopause? Definition of Menopause. Content Created  May 2022. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/185-what-is-menopause Accessed: 16 September 2024
  2. Menopause: How Menopause Occurs. 17 October 2022. World Health Organization https://www.who.int/news-room/fact-sheets/detail/menopause Accessed: 16 September 2024
  3. What Is Menopause? Definition of Menopause. Content Created  May 2022. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/185-what-is-menopause Accessed: 16 September 2024
  4. Symptoms of Menopause: Physical and Emotional Symptoms. Last Updated: 21 April 2024. Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-symptoms#physical-and-emotional-symptoms Accessed: 16 September 2024
  5. Hamoda, H, Mukherjee, A, Morris, E, Baldeweg, S. E., Jayasena, C. N., Briggs, P, Moger, S. Optimising the Menopause Transition: Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:1-2 https://journals.sagepub.com/doi/10.1177/20533691221104882 Accessed: 16 September 2024
  6. Hamoda, H, Mukherjee, A, Morris, E, Baldeweg, S. E., Jayasena, C. N., Briggs, P, Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:3-4. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 16 September 2024
  7. Emotional Wellness In Menopause: What Treatments Are Available? Published Date: June 2023:1. Women’s Health Concern https://www.womens-health-concern.org/help-and-advice/menopause-wellness-hub/ Accessed: 16 September 2024
  8. What Is Menopause? When To See Your Doctor. Last Updated: 18 January 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/about-menopause Accessed: 16 September 2024
  9. Menopause: Diagnosis & Treatment – Treatment. 25 May 2023. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/menopause/diagnosis-treatment/drc-20353401 Accessed: 16 September 2024
Topic Last Updated: 16 September 2024 – Topic Last Reviewed: 16 September 2024

“If you decide to use hormone therapy, use it at the lowest
dose that helps. Also use hormones
for the shortest time that you need them”.1

Umbrella

What may the Hormone Therapy Benefits and Risks Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • HRT/HT/MHT Benefits and Risks
  • HRT/HT/MHT Health Benefits and Risks
  • HRT/HT/MHT Pros and Cons
  • HRT/HT/MHT Risks and Benefits
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)

Date

What can it be important to be clear about with hormone therapy (HT) benefits and risks information?

It can be important to be clear about the date of all information including the date of HT benefits and risks information, because this information may have been updated.

Symptoms or Chronic Conditions

What can it also be important to be clear about with HT benefits and risks information?

It can also be important to be clear about whether HT benefits and risks information is about the use of HT for the management of menopausal symptoms such as hot flushes, night sweats and vaginal dryness or for the prevention of chronic conditions such as cardiovascular disease, cancer and osteoporosis.

Hormone Therapy

What is hormone therapy (HT) or menopausal hormone therapy (MHT)?

Depending on the Source the definition of HT may vary. In Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Is MHT? the (Australian) Jean Hailes for Women’s Health (JH) definition is:

“Menopausal hormone therapy (MHT), formerly known as hormone replacement therapy (HRT), helps manage menopausal symptoms when they interfere with your life. Menopausal symptoms are caused by lowering levels of oestrogen hormones. MHT is the medical replacement of female hormones oestrogen and progesterone, and sometimes testosterone”.2

Benefits and Risks Differences

Can HT benefits and risks differ?

Yes. HT benefits and risks can differ. These differences may include:

Hormone Therapy Benefits and Risks Differences

  1. Benefit Differences
  2. Risk Differences
  3. Individual Differences
  4. Symptom Differences
  5. Age Differences
  6. Postmenopause Differences
  7. Health Conditions Differences
  8. Uterus Differences
  9. EPT and ET Differences
  10. Product Differences
  11. Option Differences
  12. Duration Differences
  13. Breast Cancer Risk
  14. Bone Loss and Fracture Benefits

1. Benefit Differences

Can HT benefits differ?

In Risks and Benefits of MHT: Key Points the Australasian Menopause Society note:

“For the majority of symptomatic women, the benefits of menopausal hormone therapy (MHT) outweigh the risks”.3

On page three in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

“For most women, initiating HRT has a favourable benefit/risk profile. However, HRT should not be used without a clear indication and should not be used for the sole purpose of disease prevention”.4

In Hormone Replacement Therapy (HRT): Benefits and Risks of Hormone Replacement Therapy (HRT) the (United Kingdom) NHS elaborate on:

“The benefits and risks of taking HRT depend on your age, your menopause symptoms and any risk factors you have.

If you’re under 60 years old, have menopause symptoms, and are not at high risk of breast cancer or blood clots, the benefits of HRT are likely to outweigh the risks.

Talk to a GP, who will help you decide”.5

2. Risk Differences

Can HT risks differ?

In Menopause: Menopause – Hormone Therapy: What Are the Risks of Using Hormone Therapy? the (United States) U.S. Food and Drug Administration (FDA) note:

“For some women, hormone therapy may increase their chances of getting blood clots, heart attacks, strokes, breast cancer, and gall bladder disease. For a woman with a uterus, estrogen increases the chance of getting endometrial cancer (cancer of the uterine lining). Adding progestin lowers this risk”.6

3. Individual Differences

Can HT individual benefits and risks differ?

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, one of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use”.7

4. Symptom Differences

Can HT benefits and risks differ for different menopause symptoms?

On page 767 in The 2022 Hormone Therapy Position Statement of the North American Menopause Society: Abstract  “endorsed by more than 20 well-respected international organizations”, published July 2022, the North American Menopause Society (NAMS) note:

“For bothersome genitourinary syndrome of menopause symptoms not relieved with over-the-counter therapies in women without indications for use of systemic hormone therapy, low-dose vaginal estrogen therapy or other therapies (eg, vaginal dehydroepiandrosterone or oral ospemifene) are recommended”.8

5. Age Differences

Can HT benefits and risks differ for different ages?

In Hormone Therapy: Is Hormone Therapy Safe? the Menopause Society (formerly the North American Menopause Society) explain:

“For most women, experts agree that HT helps to control moderate to severe menopause symptoms such as hot flashes and vaginal dryness within 10 years of menopause and up to age 59 years. Also, women should use the lowest dose for the shortest amount of time needed to keep the symptoms under control”.9

6. Postmenopause Differences

Can HT benefits and risks differ according to if you’ve been postmenopausal for 10 years or more?

In Ongoing Individualized Hormone Therapy Appears to Have No Age Limit, published 04 September 2024, the Menopause Society note:


Hormone Therapy Benefits and Risks“The Menopause Society’s 2022 Hormone Therapy Position Statement advises that women aged older than 65 years can continue using hormone therapy (HT) with appropriate counseling and risk assessment. A new retrospective analysis demonstrates that it’s not unusual for women aged as old as 80 years to still benefit from HT. Results of the analysis will be presented at the 2024 Annual Meeting of The Menopause Society in Chicago September 10-14”.10

7. Health Conditions Differences

Can HT benefits and risks differ for different health conditions?

In Hormone Replacement Therapy (HRT): When HRT Is Not Suitable, last updated 03 November 2022, the (Scottish) NHS Inform explain:

“HRT may not be suitable, or a specialist opinion may be needed, if you:

  • Have a history of breast cancer, ovarian cancer or womb (uterus) cancer
  • Have a history of blood clots, tablet HRT is not recommended but taking HRT through the skin can be considered
  • Have a history of heart disease or stroke
  • Have untreated high blood pressure – your blood pressure will need to be controlled before you can start HRT
  • Have liver disease
  • Are pregnant or breastfeeding”.11

In Menopause: Hormone Therapy – Who Should Not Take Hormone Therapy for Menopause?, published 14 December 2023, the FDA note:

“Women who:

  • Think they are pregnant
  • Have problems with vaginal bleeding
  • Have certain kinds of cancers
  • Have had a stroke or heart attack
  • Have had blood clots
  • Have liver disease”.12

8. Uterus Differences

Can HT benefits and risks differ for those who have a uterus?

Hormone Therapy Benefits and RisksOn page one in Deciding About Hormone Use, published July 2022, the NAMS note:

“Because estrogen stimulates the lining of the uterus, women with a uterus need to take an additional hormone, progestogen, to protect the uterus”.13

Hormone Therapy Benefits and RisksIf you do not have a uterus, on page one in Deciding About Hormone Use, the NAMS also note:

“Women without a uterus just take estrogen”.14

9. ET and EPT Differences

Can HT benefits and risks differ for those who use ET and those who use EPT?

In Hormone Therapy: Is Hormone Therapy Safe? the Menopause Society explain:

“You and your healthcare professional need to balance your individual benefits and risks based on your medical history. For example, if you don’t have a uterus and can take ET alone, your risks are different from those women who still have a uterus and must use EPT to protect against uterine cancer”.15

10. Product Differences

Can HT benefits and risks differ for different HT products?

On page two in Deciding About Hormone Use: Pill or Non-Pill the NAMS explain:

“Hormone therapy is available as a daily pill, but it also may be taken as a skin patch, gel, cream, spray, or vaginal ring. Non-pill forms may be more convenient. Hormone therapy pills need to be taken every day, but skin patches are changed only once or twice weekly, and the HT vaginal ring is changed only every 3 months. Hormone therapy taken in non-pill form enters your blood stream more directly, with less effect on the liver. Studies suggest that this may lower the risk of blood clots in the legs and lungs compared with HT taken as a pill”.16

11. Option Differences

Can HT benefits and risks differ for different HT options?

On page 767 in The North American Menopause Society Releases Its 2022 Hormone Therapy Position Statement: Abstract the NAMS note:

“The risks of hormone therapy differ depending on type, dose, duration of use, route of administration, timing of initiation, and whether a progestogen is used”.17

In Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Are the Risks of MHT?, last updated 03 September 2024, the JH note:

“Research shows there are some risks associated with MHT. The risks of hormone therapy differ depending on:

  • The type of medication
  • The dose given
  • How long the medication is used for
  • How the medication is given (e.g. patch or tablet)
  • When medication is started
  • Whether a progestogen is used
  • The type of progestogen used”.18

12. Duration Differences

Can HT benefits and risks differ for those who choose to use HT for different duration or lengths of time?

In Menopause: Menopause – Hormone Therapy: How Long Should I Use Hormone Therapy for Menopause Symptoms? the FDA note:

“Treatment of menopausal symptoms should be decided with your health care provider, as there are many different FDA-approved hormones for treatment of the symptoms of menopause”.19

13. Breast Cancer Risk

Can HT increase breast cancer risk?

On page one in Deciding About Hormone Use: Potential Risks the NAMS explain:

“Hormone therapy (combined estrogen and progestogen) might slightly increase your risk of breast cancer if used for more than 4 to 5 years. Using estrogen alone (for women without a uterus) does not increase breast cancer risk at 7 years but may increase risk if used for a longer time”.20

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause one of the recommendations is:

  • “Current evidence suggests that oestrogen alone HRT is associated with a lower risk of breast cancer than combined HRT. Breast cancer risk is duration dependent and may vary with the type of progestogen used. The risk of breast cancer should be considered in the context of the overall benefits and risks associated with HRT intake”.21

14. Bone Loss Benefit

Can HT prevent bone loss and fractures?

In The 2023 Practitioner’s Toolkit for Managing Menopause: Management – Considerations for All Women At Menopause: Menopausal Hormone Therapy, published online 30 October 2023, the authors explain:

  • “MHT prevents bone loss and fractures in postmenopausal women”.22

Health Care Provider

What if I choose to use HT, how can I find out what my benefits and risks are?

If you choose to use HT, it may be in your best interest to also choose to talk to your health care provider about this.

On page one in Deciding About Hormone Use the NAMS explain:


Hormone Therapy Benefits and Risks“Every woman is different, and you will decide about whether to use HT based on the severity of your symptoms, your personal and family health history, and your own beliefs about menopause treatments. Your healthcare professional will be able to help you with your decision”.23

In Menopause: Hormone Therapy – What Is Hormone Therapy for Menopause?, published 14 December 2023, the FDA note:

“Menopause hormone therapy is not for everyone. Like all medicines, hormone therapy has benefits and risks. Talk with your health care provider about hormone therapy. If you decide to use hormone therapy, use it at the lowest dose that helps. Also use hormones for the shortest time that you need them”.24

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  1. Menopause: Hormone Therapy – What Is Hormone Therapy for Menopause? Content Current As of: 14 December 2023. Food and Drug Administration https://www.fda.gov/consumers/womens-health-topics/menopause Accessed: 15 September 2024
  2. Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Is MHT? Last Updated: 03 September 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 15 September 2024
  3. Risks and Benefits of MHT: Key Points. Content Updated January 2021. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/risks-and-benefits-of-mht-hrt Accessed: 15 September 2024
  4. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:3. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 15 September 2024
  5. Hormone Replacement Therapy (HRT): Benefits and Risks of Hormone Replacement Therapy (HRT). Page Last Reviewed: 08 February 2023. NHS https://www.nhs.uk/medicines/hormone-replacement-therapy-hrt/benefits-and-risks-of-hormone-replacement-therapy-hrt/ Accessed: 15 September 2024
  6. Menopause: Hormone Therapy – What Are the Risks of Using Hormone Therapy? Content Current As of: 14 December 2023. Food and Drug Administration https://www.fda.gov/consumers/womens-health-topics/menopause Accessed: 15 September 2024
  7. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 15 September 2024
  8. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Abstract. July 2022:767. North American Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 15 September 2024
  9. Hormone Therapy: Is Hormone Therapy Safe? Menopause Society https://menopause.org/patient-education/menopause-topics/hormone-therapy Accessed: 15 September 2024
  10. Ongoing Individualized Hormone Therapy Appears to Have No Age Limit. 04 September 2024. Menopause Society https://menopause.org/press-releases/ongoing-individualized-hormone-therapy-appears-to-have-no-age-limit 15 September 2024
  11. Hormone Replacement Therapy (HRT): When HRT Is Not Suitable. Last Updated 03 November 2022. NHS Inform https://www.nhsinform.scot/tests-and-treatments/medicines-and-medical-aids/types-of-medicine/hormone-replacement-therapy-hrt/ Accessed: 15 September 2024
  12. Menopause: Hormone Therapy – Who Should Not Take Hormone Therapy for Menopause? Content Current As of: 14 December 2023. Food and Drug Administration https://www.fda.gov/consumers/womens-health-topics/menopause Accessed: 15 September 2024
  13. Deciding About Hormone Therapy Use. 2022:1. Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 15 September 2024
  14. Deciding About Hormone Therapy Use. 2022:1. Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 15 September 2024
  15. Hormone Therapy: Is Hormone Therapy Safe? Menopause Society https://menopause.org/patient-education/menopause-topics/hormone-therapy Accessed: 15 September 2024
  16. Deciding About Hormone Therapy Use: Pill or Non-Pill. 2022:2. Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 15 September 2024
  17. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Abstract. Menopause, Volume 29, No 27, 2022:767. Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 15 September 2024
  18. Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Are the Risks of MHT? Last Updated: 03 September 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 15 September 2024
  19. Menopause: Hormone Therapy – How Long Should I Use Hormone Therapy for Menopause Symptoms? Content Current As of: 14 December 2023. Food and Drug Administration https://www.fda.gov/consumers/womens-health-topics/menopause Accessed: 15 September 2024
  20. Deciding About Hormone Therapy Use: Potential Benefits. 2022:2. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 15 September 2024
  21. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:2. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 15 September 2024
  22. Davis, S. R., Taylor, S., Hemachandra, C., Magraith, K., Ebeling, P. R., Jane, F., and Islam, R. M. The 2023 Practitioner’s Toolkit for Managing Menopause: Management – Considerations for All Women At Menopause: Menopausal Hormone Therapy First Published Online: 30 October 2023 https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783 Accessed: 15 September 2024
  23. Deciding About Hormone Therapy Use. 2022:1. North American Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 15 September 2024
  24. Menopause: Hormone Therapy – What Is Hormone Therapy for Menopause? Content Current As of: 14 December 2023. Food and Drug Administration https://www.fda.gov/consumers/womens-health-topics/menopause Accessed: 15 September 2024
Topic Last Updated: 15 September 2024 – Topic Last Reviewed: 15 September 2024

“The average age of the menopause is around fifty
and in the months or years leading up to this,
some people notice a change in hair pattern”.1

Umbrella

What may the Menopause Hair Changes Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Chin Hair
  • Downy Hair
  • Facial Hair Growth/Increase
  • Hair Loss
  • Head Hair
  • Hirsutism
  • Thinning Hair
  • “Peach Fuzz”
  • “Rogue Hair”

Menopause

Is there an association between menopause and hair pattern?

On page one in Menopausal Hair Loss – ‘More Than A Bad Hair Day’ the (British) Women’s Health Concern (WHC) explain:

“The average age of the menopause is around fifty and in the months or years leading up to this, some people notice a change in hair pattern. Very commonly, the volume and condition of the hair appears to worsen, with some women noticing that hair does not grow as much as previously. More hair seems to come out in the basin when washing and hair brushes soon fill up as loose hairs are brushed away”.2

Postmenopause

Is there an association between postmenopause and hair loss?

In Treating Female Pattern Hair Loss the (United States) Harvard Health Publishing, Harvard Health explain:

“About one-third of women experience hair loss (alopecia) at some time in their lives; among postmenopausal women, as many as two-thirds suffer hair thinning or bald spots”.3

Female Pattern Hair Loss

Is there an association between menopause and female pattern hair loss (FPHL)?

In Menopausal Hair Loss – ‘More Than A Bad Hair Day’ the WHC note:

“FPHL is very common and increases with age and varies across ethnic groups. Although it can happen at any age, the condition occurs most commonly following the menopause. This does not mean that hormones alone are to blame, although oestrogen may have a protective role, helping to keep hair in the ‘growing phase’. Age itself is a factor and whilst women can take care of their hair cosmetically, it is one aspect of the ageing process we cannot always control”.4

In Treating Female Pattern Hair Loss Harvard Health Publishing, Harvard Health elaborate on:

“The main type of hair loss in women is the same as it is men. It’s called androgenetic alopecia, or female (or male) pattern hair loss. In men, hair loss usually begins above the temples, and the receding hairline eventually forms a characteristic “M” shape; hair at the top of the head also thins, often progressing to baldness. In women, androgenetic alopecia begins with gradual thinning at the part line, followed by increasing diffuse hair loss radiating from the top of the head. A woman’s hairline rarely recedes, and women rarely become bald”.5

Androgenetic Alopecia

What is androgenetic alopecia?

In Treating Female Pattern Hair Loss: What Is Androgenetic Alopecia? Harvard Health Publishing, Harvard Health explain:


Menopause Hair Changes“Almost every woman eventually develops some degree of female pattern hair loss. It can start any time after the onset of puberty, but women tend to first notice it around menopause, when hair loss typically increases. The risk rises with age, and it’s higher for women with a history of hair loss on either side of the family”.6

Hirsutism

What is hirsutism?

DotS the definition of hirsutism may vary. In Hirsutism: Overview the (United States) Mayo Clinic’s definition is:

“Hirsutism (HUR-soot-iz-um) is a condition in women that results in excessive growth of dark or coarse hair in a male-like pattern — face, chest and back”.7

Health Care Provider

What if I would like help with hair changes?

If you would like help with hair changes, it may be in your best interest to choose to talk to your health care provider about this. Together you can clarify your hair changes, discuss your options and if required, agree on who may be the most appropriate health care provider to help you.

In Menopausal Hair Loss – ‘More Than A Bad Hair Day’: When To Seek Help the WHC explain:

“You should consult your doctor if:

  • You are losing hair in an unusual pattern
  • You are losing hair rapidly or at an early age (for example, in your teens or twenties)
  • You have any pain or itching with the hair loss
  • The skin on your scalp under the involved area is red, scaly, or otherwise abnormal
  • You have acne, facial hair, or an abnormal menstrual cycle
  • You have additional symptoms which concern you”.8

Health Topics A-Z

Where may I find Health Topics A-Z related to Menopause Hair Changes?

In Health Topics A-Z you may find:

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Where may I find Links related to Menopause Hair Changes?

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  1. Menopausal Hair Loss – ‘More Than A Bad Hair Day’. Publication Date: August 2021:1. Women’s Health Concern https://www.womens-health-concern.org/help-and-advice/factsheets/menopausal-hair-loss/ Accessed: 14 September 2024
  2. Menopausal Hair Loss – ‘More Than A Bad Hair Day’. Publication Date: August 2021:1. Women’s Health Concern https://www.womens-health-concern.org/help-and-advice/factsheets/menopausal-hair-loss/ Accessed: 14 September 2024
  3. Treating Female Pattern Hair Loss. 08 April 2024. Harvard Health Publishing, Harvard Health https://www.health.harvard.edu/staying-healthy/treating-female-pattern-hair-loss Accessed: 14 September 2024
  4. Menopausal Hair Loss – ‘More Than A Bad Hair Day’. Publication Date: August 2021:1. Women’s Health Concern https://www.womens-health-concern.org/help-and-advice/factsheets/menopausal-hair-loss/ Accessed: 14 September 2024
  5. Treating Female Pattern Hair Loss. 08 April 2024. Harvard Health Publishing, Harvard Health https://www.health.harvard.edu/staying-healthy/treating-female-pattern-hair-loss Accessed: 14 September 2024
  6. Treating Female Pattern Hair Loss: What Is Androgenetic Alopecia? 08 April 2024. Harvard Health Publishing, Harvard Health https://www.health.harvard.edu/staying-healthy/treating-female-pattern-hair-loss Accessed: 14 September 2024
  7. Hirsutism: Overview. 12 October 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/hirsutism/symptoms-causes/syc-20354935 Accessed: 14 September 2024
  8. Menopausal Hair Loss – ‘More Than A Bad Hair Day’: When To Seek Help. Publication Date: August 2021:2. Women’s Health Concern https://www.womens-health-concern.org/help-and-advice/factsheets/menopausal-hair-loss/ Accessed: 23 March 2024
Topic Last Updated: 14 September 2024 – Topic Last Reviewed: 14 September 2024

“By taking steps toward healthy living,
you can help reduce your risk of heart disease,
cancer, stroke and other serious diseases”.1

Umbrella

What may the Healthy Living Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Healthy Lifestyle
  • Healthy Living
  • Lifestyle Management

Healthy Living Steps

What are some healthy living steps?

In Healthy Living the (United States) MedlinePlus elaborate on:


Healthy Living“Many factors affect your health. Some you cannot control, such as your genetic makeup or your age. But you can make changes to your lifestyle. By taking steps toward healthy living, you can help reduce your risk of heart disease, cancer, stroke and other serious diseases:

  • Get the screening tests you need
  • Maintain a healthy weight
  • Eat a variety of healthy foods, and limit calories and saturated fat
  • Be physically active
  • Control your blood pressure and cholesterol
  • Don’t smoke
  • Protect yourself from too much sun
  • Drink alcohol in moderation, or don’t drink at all
  • Get enough sleep every day
  • Work on improving your mental health, for example by practicing mediation, relaxation techniques, or gratitude”.2

Health Care Provider

What if I would like help with healthy living?

If you would like help with healthy living, it may be in your best interest to choose to talk to your health care provider about this. Together you can discuss your options and if required, agree on who may be the most appropriate health care provider to help you.

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  1. Healthy Living: Summary. Last Updated: 26 April 2023. MedlinePlus https://www.nlm.nih.gov/medlineplus/healthyliving.html Accessed: 14 September 2024
  2. Healthy Living: Summary. Last Updated: 26 April 2023. MedlinePlus https://www.nlm.nih.gov/medlineplus/healthyliving.html Accessed: 14 September 2024
Topic Last Updated: 14 September 2024 – Topic Last Reviewed: 14 September 2024

“Because estrogen stimulates the lining of the uterus, women with a uterus need to take an additional hormone, progestogen, to protect the uterus”.1

Umbrella

What may the Hormone Therapy and Estrogen Plus Progestogen Therapy Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Combination Estrogen and Progestin Medicines
  • Combination HT/HRT
  • Combination Hormone Replacement/Hormone Therapy
  • Combined Hormonal Therapy
  • Combined Hormone Replacement Therapy
  • Estrogen Plus Progestogen
  • Estrogen With Progestogen Therapy
  • Estrogen and Progestin (Hormone Replacement Therapy)
  • Estrogen-Progestogen Therapy (EPT)
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Menopausal Hormone Therapy (MHT)
  • Oestrogen and Progesterone Therapy

Hormone Therapy

What is hormone therapy (HT) or menopausal hormone therapy (MHT) ?

DotS the definition of HT or MHT may vary. In Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Is MHT? the (Australian) Jean Hailes for Women’s Health’s definition is:

“MHT is the medical replacement of female hormones oestrogen and progesterone, and sometimes testosterone”.2

Progesterone

What is progesterone?

DotS the definition of progesterone may vary. In Glossary of Terms the Australasian Menopause Society’s (AMS) definition is:

“Progesterone is the ovarian hormone produced by the corpus luteum which prepares the endometrium for implantation of the fertilized egg”.3

Progestogen

What is progestogen?

DotS the definition of progestogen may vary. The AMS’s definition is:

“Progestogen is a hormone which can be natural or synthetic but has a similar effect on a woman’s body as progesterone”.4

Progestin

What is progestin?

DotS the definition of progestin may vary. The AMS’s definition is:

“Progestin is a synthetic hormone which has the actions of progesterone”.5

UterusHormone Therapy and Estrogen Plus Progestogen Therapy

Who can choose to use estrogen plus progestogen hormone therapy (HT)?

On page one in Deciding About Hormone Therapy Use, published July 2022, the North American Menopause Society elaborate on:

“Hormone therapy involves taking estrogen in doses high enough to raise the level of estrogen in your blood in order to treat hot flashes and other symptoms. Because estrogen stimulates the lining of the uterus, women with a uterus need to take an additional hormone, progestogen, to protect the uterus”.6

In Menopause Management Options: Menopausal Hormone Therapy (MHT) – Types of MHT: Oestrogen and Progesterone Therapy the JH explain:

“If you haven’t had a hysterectomy, oestrogen and progesterone are used together, as progesterone reduces the risk of endometrial cancer (cancer of the uterus).

Other combinations of oestrogen and progestogen (including progesterone and other progesterone-like hormones) may also be recommended”.7

Health Care Provider

If I choose to use estrogen plus progestogen (EPT) what are my risks?

Different women who choose to use EPT can have different risks. It may therefore be in your best interest to also choose to talk to your health care provider about this.

On page two in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause first published online 10 June 2022, one of the recommendations is:

  • “The decision whether to take HRT, the dose and duration of its use should be made on an individualised basis after discussing the benefits and risks with each patient. This should be considered in the context of the overall benefits obtained from using HRT including symptom control and improving quality of life as well as considering the bone and cardiovascular benefits associated with HRT use”.8

Health Topics A-Z

Where may I find Health Topics A-Z related to Hormone Therapy and Estrogen Plus Progestogen Therapy?

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Sources

  1. Deciding About Hormone Therapy Use. 2022:1. Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 12 September 2024
  2. Menopause Management Options: Menopausal Hormone Therapy (MHT) – What Is MHT? Last Updated: 03 September 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 12 September 2024
  3. Glossary of Terms: Progesterone. Content Updated: February 2022. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/381-glossary-of-terms Accessed: 12 September 2024
  4. Glossary of Terms: Progestogen. Content Updated: February 2022. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/381-glossary-of-terms Accessed: 12 September 2024
  5. Glossary of Terms: Progestin. Content Updated: February 2022. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/381-glossary-of-terms Accessed: 12 September 2024
  6. Deciding About Hormone Therapy Use. 2022:1. Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 12 September 2024
  7. Menopause Management Options: Menopausal Hormone Therapy (MHT) – Types of MHT: Oestrogen and  Progesterone Therapy. Last Updated: 03 September 2024 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-management Accessed: 12 September 2024
  8. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayasena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022:3-4. https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 12 September 2024
Topic Last Updated: 12 September 2024 – Topic Last Reviewed: 12 September 2024

“Genitourinary syndrome of menopause is caused by
a decrease in estrogen production. Less estrogen
makes your vaginal tissues thinner, drier, less elastic…”.1

Umbrella

What may the Genitourinary Syndrome of Menopause Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Atrophic Vaginitis
  • Genital Atrophy
  • Genitourinary/Genito-Urinary Syndrome of Menopause (GSM)
  • Menopause Vaginal Dryness
  • Urogenital Problems
  • Vaginal Atrophy
  • Vaginal Dryness
  • Vaginal Symptoms
  • Vulvovaginal Atrophy (VVA)

Definition

What is the genitourinary syndrome of menopause (GSM)?

DotS the definition of GSM may vary. On page one in Vaginal Dryness the (United States) Menopause Society elaborate on:

“The genitourinary syndrome of menopause (GSM) includes bothersome vaginal, vulvar (lips of the vagina), and urinary symptoms that can affect quality of life, sexual satisfaction, and even your relationship with your partner”.2

In Mayo Clinic Q and A: Treatment for Vaginal Dryness for Menopausal Women the (United States) Mayo Clinic elaborate on:

“Vaginal dryness is common in women who are approaching menopause and those who have gone through menopause. Other related symptoms include vaginal and vulvar irritation; burning or itching; discomfort or pain with sexual activity; and urinary symptoms, such as more frequent or urgent urination, urge leak, and urinary tract infections. Together, these symptoms are referred to as “genitourinary syndrome of menopause,” or GSM. These symptoms occur in roughly half of menopausal women and are even more common in women with breast cancer”.3

Common or Not

How common is GSM in postmenopausal women?

In Symptoms of Menopause: Bladder, Vaginal and Vulval Problems the (Australian) Jean Hailes for Women’s Health (JH) explain:

“As you move into perimenopause and menopause, low oestrogen levels can change your vulval, vaginal and bladder tissues. These changes may affect up to half of postmenopausal women”.4

Symptoms

What may be symptoms of GSM?

In Vaginal Atrophy: Symptoms & Causes – Symptoms the Mayo Clinic explain:

“Genitourinary syndrome of menopause (GSM) signs and symptoms may include:

  • Vaginal dryness
  • Vaginal burning
  • Vaginal discharge
  • Genital itching
  • Burning with urination
  • Urgency with urination
  • Frequent urination
  • Recurrent urinary tract infections
  • Urinary incontinence
  • Light bleeding after intercourse
  • Discomfort with intercourse
  • Decreased vaginal lubrication during sexual activity
  • Shortening and tightening of the vaginal canal”.5

Cause

What causes GSM?

In Vaginal Atrophy: Symptoms & Causes – Causes the Mayo Clinic elaborate on:

“Genitourinary syndrome of menopause is caused by a decrease in estrogen production. Less estrogen makes your vaginal tissues thinner, drier, less elastic and more fragile”.6

Treatment

What are some GSM treatments?

On page one and two in Vaginal Dryness: Treatment Options the Menopause Society elaborate on:

Menopause“There are many effective treatment options for GSM, including over-the-counter and prescription therapies. First-line therapies for less severe symptoms include nonhormone over-the-counter lubricants used as needed for sexual activity and moisturizers used regularly (several times per week) to maintain moisture. Prescription therapies include low-dose vaginal estrogens, vaginal dehydroepiandrosterone inserts, and oral ospemifene. Nonhormone lubricants and moisturizers can be combined for optimal symptom relief and can be used in combination with prescription therapies for more severe symptoms.

  • “Nonhormone Remedies
    • Vaginal Lubricants…
    • Vaginal Moisturizers…
    • Regular Sexual Stimulation…
    • Expanding Your Views of Sexual Pleasure…
    • Vaginal Dilators…
    • Pelvic Floor Exercises…
  • Vaginal Hormone Therapy…
    • An effective and safe treatment, low-dose local estrogen applied directly to the vagina…
    • FDA-approved low-dose vaginal estrogen products…
    • Dehydroepiandrosterone (DHEA; Prasterone)
    • Low-dose vaginal estrogen or DHEA may be options for women with a history breast or uterine cancer…
  • Systemic Estrogen Therapy
  • Other Therapies…
    • Ospemifene
    • Vaginal Laser Therapy…”.7

Painful Intercourse

How may painful intercourse be resolved?

The Mayo Clinic explain:

“… make an appointment to see your doctor if you experience painful intercourse that’s not resolved by using a vaginal moisturizer (K-Y Liquibeads, Replens, Sliquid, others) or water-based lubricant (Astroglide, K-Y Jelly, Sliquid, others)”.8

Vaginal Estrogen

How may vaginal estrogen be used?

In The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Abstract published July 2022, the Menopause Society note:

“For bothersome genitourinary syndrome of menopause symptoms not relieved with over-the-counter therapies in women without indications for use of systemic hormone therapy, low-dose vaginal estrogen therapy or other therapies (eg, vaginal dehydroepiandrosterone or oral ospemifene) are recommended”.9

Can estrogen be placed directly into the vagina?

On page one in Deciding About Hormone Therapy Use, published July 2022, the NAMS explain:

“If you are bothered only by vaginal dryness, you can use very low doses of estrogen placed directly into the vagina. These low doses generally do not raise blood estrogen levels above postmenopause levels and do not treat hot flashes. You do not need to take a progestogen when using only low doses of estrogen in the vagina. (The MenoNoteVaginal Dryness” covers this topic in detail)”.10

On page three in the Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause, first published online 10 June 2022, one of the recommendations is:

  • “Low-dose and ultra-low dose vaginal oestrogen preparations can be taken by perimenopausal and menopausal women experiencing genitourinary symptoms and continued for as long as required. All vaginal oestrogen preparations have been shown to be effective in this context and there is no requirement to combine vaginal oestrogens with systemic progestogen treatment for endometrial protection, as low-dose and ultra-low dose vaginal oestrogen preparations do not result in significant systemic absorption or endometrial hyperplasia”.11

Health Care Provider

What if I think I have GSM?

If you think you have GSM, it may be in your best interest to choose to talk to your health care provider about this.

In The 2023 Practitioner’s Toolkit for Managing Menopause – Effectiveness: Local Treatment of Urogenital Atrophy, published online 01 December 2023, the authors note:

“Urogenital symptoms due to estrogen insufficiency are under-recognized and under-treated. These symptoms can be effectively treated with an array of local therapies including intravaginal estrogen preparations or DHEA (prasterone) and intravaginal moisturizers. Concurrent progestogen therapy is not required. Many women require local therapy, in addition to systemic MHT, to relieve urogenital symptoms. It is important patients understand that treatment needs to be ongoing and is not simply a short course of therapy”.12

In Symptoms of Menopause: Bladder, Vaginal and Vulval Problems – Urinary Symptoms the JH explain:

“While symptoms such as hot flushes usually disappear over time, bladder, vaginal and vulval problems can persist and may even get worse. But many effective treatments are available.”.13

On page two in Vaginal Dryness the Menopause Society also note:

“Note: Vaginal and vulvar symptoms not related to menopause include yeast infections, allergic reactions, and certain skin conditions, so consult your healthcare professional if symptoms do not improve with treatment”.14

Health Topics A-Z

Where may I find Health Topics A-Z related to Genitourinary Syndrome of Menopause?

In Health Topics A-Z you may find:

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Sources

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Sources

  1. Vaginal Atrophy: Symptoms & Causes – Causes. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/symptoms-causes/syc-20352288 Accessed: 12 September 2024
  2. Vaginal Dryness. 2022: 1. Menopause Society https://menopause.org/wp-content/uploads/for-women/mn-vaginal-dryness_4e454569-8d3c-4346-a00b-515f46b378c9.pdf Accessed: 12 September 2024
  3. Mayo Clinic Q and A: Treatment for Vaginal Dryness for Menopausal Women. 14 July 2021. Mayo Clinic https://newsnetwork.mayoclinic.org/discussion/mayo-clinic-q-and-a-treatment-for-vaginal-dryness-for-menopausal-women/ Accessed: 12 September 2024
  4. Symptoms of Menopause: Bladder, Vaginal and Vulval Problems. Last Updated: 21 April 2024. Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-symptoms/ Accessed: 12 September 2024
  5. Vaginal Atrophy: Symptoms & Causes – Symptoms. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/symptoms-causes/syc-20352288 Accessed: 12 September 2024
  6. Vaginal Atrophy: Symptoms & Causes – Causes. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/symptoms-causes/syc-20352288 Accessed: 12 September 2024
  7. Vaginal Dryness: Treatment Options. 2022: 1-2. Menopause Society https://menopause.org/wp-content/uploads/for-women/mn-vaginal-dryness_4e454569-8d3c-4346-a00b-515f46b378c9.pdf Accessed: 12 September 2024
  8. Vaginal Atrophy: Symptoms & Causes – Symptoms: When To See A Doctor. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/symptoms-causes/syc-20352288 Accessed: 12 September 2024
  9. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Abstract. Published July 2022. Menopause Society https://journals.lww.com/menopausejournal/Abstract/2022/07000/The_2022_hormone_therapy_position_statement_of_The.4.aspx Accessed: 12 September 2024
  10. Deciding About Hormone Therapy Use. Published July 2022. Menopause Society https://www.menopause.org/docs/default-source/professional/menonote-deciding-about-ht-2022.pdf Accessed: 12 September 2024
  11. Hamoda, H., Mukherjee, A., Morris, E., Baldeweg, S. E., Jayesena, C. N., Briggs, P., Moger, S. Joint Position Statement By the British Menopause Society, Royal College of Obstetricians and Gynaecologists and Society for Endocrinology on Best Practice Recommendations for the Care of Women Experiencing the Menopause. First Published Online 10 June 2022 https://journals.sagepub.com/doi/full/10.1177/20533691221104879 Accessed: 12 September 2024
  12. Davis, S. R., Taylor, S., Hemachandra, C., Magraith, K., Ebeling, P. R., Jane, F., and Islam12 September 2024, R. M. The 2023 Practitioner’s Toolkit for Managing Menopause: The 2023 Practitioner’s Toolkit for Managing the Menopause Supporting Notes – Effectiveness: Local Treatment of Urogenital Atrophy. Published Online: 30 October 2023 https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783 Accessed: 12 September 2024
  13. Symptoms of Menopause: Bladder, Vaginal and Vulval Problems – Urinary Symptoms. Last Updated: 21 April 2024. Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-symptoms/ Accessed: 12 September 2024
  14. Vaginal Dryness: Note. 2022: 2. Menopause Society https://menopause.org/wp-content/uploads/for-women/mn-vaginal-dryness_4e454569-8d3c-4346-a00b-515f46b378c9.pdf Accessed: 12 September 2024
Topic Last Updated: 12 September 2024 – Topic Last Reviewed: 12 September 2024

Menopause News November 2024 includes
some evidence-based menopause news
by menopause societies and international sources.

Umbrella

What may the Menopause News November 2024 Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Latest News
  • Media Releases
  • Menopause News
  • News
  • Position Statements
  • Press Releases/Statements
  • Reports

Date

What can it be important to be clear about with Menopause News?

It can be important to be clear about the date of all information including the date of Menopause News, because this information may have been updated.

Health Care Provider

What if I would like to find out what Menopause News November 2024 is applicable to me?

If you would like to find out what Menopause News November 2024 is applicable to you, it may be in your best interest to choose to talk to your health care provider about this.

Menopause News November 2024

What is some Menopause News November 2024?

Your Country may have Links similar to:

Health Topics A-Z

Where may I find Health Topics A-Z related to Menopause News November 2024?

In Health Topics A-Z you may find:

Links

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Your Country may have Links similar to:

Topic Last Updated: 21 September 2024 – Topic Last Reviewed: 11 September 2024

“Hormonal changes around the time of menopause
can lead to anxiety and depression,
but other factors may also cause these feelings”.1

Umbrella

What may the Menopause Depression umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Clinical Depression
  • Depression
  • Depressive Disorder
  • Major Depression
  • Major Depressive Disorder
  • Menopause Blues

Depression

What is depression?

DotS the definition of depression may vary. In Depressive Disorder (Depression): Overview, 31 March 2023, the World Health Organization’s definition is:

“Depressive disorder (also known as depression) is a common mental disorder. It involves a depressed mood or loss of pleasure or interest in activities for long periods of time.

Depression is different from regular mood changes and feelings about everyday life. It can affect all aspects of life, including relationships with family, friends and community. It can result from or lead to problems at school and at work”.2

In Depression: What Is Depression? last reviewed March 2024, the (United States) National Institute of Mental Health’s (NIMH) definition is:

“Depression (also known as major depression, major depressive disorder, or clinical depression) is a common but serious mood disorder. It causes severe symptoms that affect how a person feels, thinks, and handles daily activities, such as sleeping, eating, or working.

To be diagnosed with depression, the symptoms must be present for at least 2 weeks”.3

Sadness or Depression

Is sadness the same as depression?

In Depression In Women: 4 Things To Know the NIMH explain:

“Feeling sad is a normal reaction to difficult times in life. Depression is different—it is a mood disorder that can affect how a person feels, thinks, and acts”.4

Perimenopause

Is there an association between perimenopause and depression?

In Depression In Women: 4 Things To Know – 3. Certain Types of Depression Are Unique To Women the NIMH note:

  • “Perimenopausal Depression affects some women during the transition to menopause. Whereas abnormal periods, problems sleeping, mood swings, and hot flashes are common during the menopause transition, more extreme feelings of irritability, anxiety, sadness, or loss of enjoyment may be signs of depression”.5

Menopause

Is there an association between menopause and depression?

In Menopause Depression: Women, Menopause and Depression HER Center Australia elaborate on:

Menopause Depression“Depression in women in their mid-40’s to early 50’s is a significant problem. For women, middle age is the age with a very high risk of both first time depression as well as depression recurrence. Related to this is the tragic statistic that women aged 45-49, have a high completed suicide rate. The impact of menopause is a critical factor in the development of depression in this group, be it for the first time, or a recurrence of previous depression.

While many women do not experience significant mental ill health during the transition to menopause, an estimated 40% of perimenopausal women present to their primary healthcare physicians with depressive symptoms. Importantly, depressive symptoms experienced in the menopause transition are different and often worse in severity compared to depression in younger and older women”.6

In Menopause and Mental Health: Mental Health Symptoms Related To Menopause, content updated February 2023, the Australasian Menopause Society (AMS) elaborate on:

“Mental health symptoms related to menopause can include feeling:

  • Irritable
  • Sad
  • Anxious
  • Hopeless
  • Less able to concentrate or focus
  • Tired
  • Unmotivated

Some women might experience these symptoms in a mild form. Others might have more severe symptoms of depression (including thoughts of suicide) lasting for at least two weeks. This is known as a major depressive episode and is more likely in women who have a history of major depression during their pre-menopausal years.

While many women do not have mental health issues during the menopausal transition, unstable oestrogen levels can have an impact on the brain, predisposing some women to feelings of depression and anxiety”.7

Cause

What may cause depression during menopause?

On page 777 in The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Depression, published July 2022, the North American Menopause Society note:

“Depressive symptoms worsen as women transition through menopause, although evidence is mixed as to whether depressive disorders are more common during the menopause transition relative to premenopause. Most women who present with depressive disorders during the menopause transition are women with a history of depression before the menopause transition, and women with a history of depression are at high risk for recurrence during the menopause transition”.8

In Managing Your Symptoms: Managing Mood and Emotional Health – Anxiety and Depression the (Australian) Jean Hailes for Women’s Health explain:

“Hormonal changes around the time of menopause can lead to anxiety and depression, but other factors may also cause these feelings.

If you experienced anxiety before reaching menopause, some symptoms could make your anxiety worse. For example, hot flushes could lead to an anxiety attack.

Also, symptoms such as night sweats can affect your mood and make you feel exhausted, grumpy or depressed.

At this stage of life, you may experience depression for different reasons. For example, if you are having relationship problems or feeling more stress than normal.

You might also reflect on negative past experiences during this time, leading to feelings of depression”.9

In Mood and the Menopause, content updated 09 February 2023, the AMS elaborate on:

“Risk factors for depressive symptoms/disorders are multiple and include VMS, previous mood disorders including prior MDD, reproductive related mood disturbance (severe premenstrual syndrome (PMS) or postpartum depression), other health factors, psychological and socioeconomic factors, and hormonal changes such as variability in FSH and oestradiol”.10

What is VMS?

VMS can be an abbreviation for Vasomotor Symptoms such as hot flushes and night sweats.

What is MDD?

MDD can be an abbreviation for Major Depressive Disorder.

What is FSH?

FSH can be an abbreviation for Follicle Stimulating Hormone.

Treatment

How may perimenopausal and menopausal depression be treated?

In Menopause and Mental Health: Treatment Options for Mental Health Symptoms the AMS elaborate on:

“Women should have an individualised assessment with their doctor in order to discuss the most appropriate treatment pathway. Options may include lifestyle changes, psychological therapies and medications such as menopausal hormone therapy (MHT) or antidepressants.

While some international guidelines do not recommend MHT as first line therapy, many doctors have seen a positive effect on mood with the use of MHT in the first instance. There is evidence that oestrogen has antidepressant effects, particularly in perimenopausal women. We emphasise an individualised approach with treatment tailored to the individual patient.

Oestrogen is not recommended for women with a history of breast cancer.

At this stage, there is no evidence to recommend alternative or complementary therapies for treatment of perimenopausal depression”.11

Hormone Therapy vs Antidepressants

What does Professor Kulkarni explain about hormone therapy or menopausal hormone therapy (MHT) as a  treatment option for menopause mental health issues?

In Depression: A Major Challenge of the Menopause Transition – Abstract, published October 2022, Professor Kulkarni, Professor of Psychiatry at The Alfred Hospital, Melbourne; Head of Department of Psychiatry at Monash University, Melbourne; and Director of the Monash Alfred Psychiatry Research Centre, Melbourne, Victoria, explains:

“Guidelines recommend antidepressant medications as first-line treatment; however, emerging evidence suggests menopausal hormone treatment may also be effective. A biopsychosocial approach to management, including treating depressive symptoms and addressing relevant psychological and lifestyle factors, offers the best outcomes and improvement in quality of life”.12

In Menopause Depression: Under Recognised and Poorly Treated – A New Approach for Menopausal Mental Health, published 18 May 2024, Kulkarni, J. et al. also elaborate on:

“MHT is an important part of the treatment options available for menopausal mental health issues, particularly in the early perimenopause timeframe. The newer forms of MHT given in safer delivery modes potentially offer better outcomes for menopausal mental health and physical health issues. Coupled with comprehensive baseline and follow-up investigations, MHT may provide better resolution of menopausal depression, anxiety and ‘brain fog’ than current psychiatric medications that provide partial relief but have many side effects…”.13

Health Care Provider

What if I feel depressed?

If you feel depressed, it may be in your best interest to choose to talk to your health care provider abut this, soon as possible.

In Menopause and Mental Health: Untangling Physical and Mental Health Symptoms Related To Menopause the AMS elaborate on:

“Speaking with your doctor about your menopausal symptoms, life circumstances and clinical history can help them to recommend the best treatment options and lifestyle and behavioural changes for your situation”.14

In Menopause and Mind Health the JH remind us:

“Everyone experiences menopause differently. Talk to your doctor if:

  • You are experiencing strong emotions
  • You think you have anxiety or depression
  • Menopausal symptoms are impacting your quality of life
  • Your brain fog is long lasting or stopping you from doing daily activities”.15

In Menopause Depression: Under Recognised and Poorly Treated – A New Approach for Menopausal Mental Health, Kulkarni, J. et al. note:

“As with other mental health areas, the person with lived experience must be a key driver and collaborator in determining what treatment approaches she wants. In the area of menopausal mental health, the woman experiencing hormone-created anxiety, depression, cognitive changes (known as ‘brain fog’) and physical health issues related to menopause needs to decide what her individualised care programme includes, based on well-informed options”.16

Health Topics A-Z

Where may I find Health Topics A-Z related to Menopause Depression?

In Health Topics A-Z you may find:

Links

Where may I find Links related to Menopause Depression?

Your Country may have Links similar to:

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Managing Your Symptoms: Managing Mood and Emotional Health – Anxiety and Depression. Last Updated: 19 December 2023 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/managing-your-symptoms#managing-mood-and-emotional-health Accessed: 10 September 2024
  2. Depressive Disorder (Depression): Overview. 31 March 2023. World Health Organization https://www.who.int/news-room/fact-sheets/detail/depression Accessed: 10 September 2024
  3. Depression: What Is Depression? Last Reviewed: March 2024. National Institute of Mental Health https://www.nimh.nih.gov/health/topics/depression/index.shtml#part_145398 Accessed: 10 September 2024
  4. Depression In Women: 4 Things To Know. Revised: 2023. National Institute of Mental Health https://www.nimh.nih.gov/health/publications/depression-in-women Accessed: 10 September 2024
  5. Depression In Women: 4 Things To Know – 3. Certain Types of Depression Are Unique To Women. Revised: 2023. National Institute of Mental Health https://www.nimh.nih.gov/health/publications/depression-in-women Accessed: 10 September 2024
  6. Menopause Depression: Women, Menopause and Depression. HER Center Australia https://www.monash.edu/medicine/her-centre/education/resources/menopause-depression Accessed: 10 September 2024
  7. Menopause and Mental Health: Mental Health Symptoms Related To Menopause. Content Updated: February 2023. Australasian Menopause Society https://www.menopause.org.au/health-info/fact-sheets/menopause-and-mental-health Accessed: 10 September 2024
  8. The 2022 Hormone Therapy Position Statement of The North American Menopause Society: Depression. Menopause: The Journal of the North American Menopause Society Vol: 29, No. 7, pp 767-794. North American Menopause Society https://www.menopause.org/docs/default-source/professional/nams-2022-hormone-therapy-position-statement.pdf Accessed: 10 September 2024
  9. Managing Your Symptoms: Managing Mood and Emotional Health – Anxiety and Depression. Last Updated: 19 December 2023 | Last Reviewed: 19 August 2022. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/managing-your-symptoms#managing-mood-and-emotional-health Accessed: 10 September 2024
  10. Mood and the Menopause. Content Updated: 09 February 2023. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/mood-and-the-menopause Accessed: 10 September 2024
  11. Menopause and Mental Health: Treatment Options for Mental Health Symptoms. Content Updated February 2023. Australasian Menopause Society https://www.menopause.org.au/health-info/fact-sheets/menopause-and-mental-health Accessed: 10 September 2024
  12. Kulkarni, J. et al. Depression: A Major Challenge of the Menopause Transition – Abstract. October 2022 https://medicinetoday.com.au/mt/2022/october/feature-article/depression-major-challenge-menopause-transition Accessed: 10 September 2024
  13. Kulkarni, J. et al. Menopause Depression: Under Recognised and Poorly Treated – A New Approach for Menopausal Mental Health. 18 May 2024 https://journals.sagepub.com/doi/10.1177/00048674241253944 Accessed: 10 September 2024
  14. Menopause and Mental Health: Untangling Physical and Mental Health Symptoms Related To Menopause. Content Updated: February 2023. Australasian Menopause Society https://www.menopause.org.au/health-info/fact-sheets/menopause-and-mental-health Accessed: 10 September 2024
  15. Menopause and Mind Health: When To See Your Doctor. Updated: May 2023. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/resources/menopause-and-mind-health Accessed: 10 September 2024
  16. Kulkarni, J. et al. Menopause Depression: Under Recognised and Poorly Treated – A New Approach for Menopausal Mental Health. 18 May 2024 https://journals.sagepub.com/doi/10.1177/00048674241253944 Accessed: 10 September 2024
Topic Last Updated: 10 September 2024 – Topic Last Reviewed: 10 September 2024