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2023 Nonhormone Therapy Position Statement of The North American Menopause Society

What were the Results in the 2023 Nonhormone Therapy Position Statement of The North American Menopause Society?

On page one in the The 2023 Nonhormone Therapy Position Statement of The North American Menopause Society: Abstract – Results, published May 2023, the North American Menopause Society (NAMS) (now the Menopause Society) include:

Results: Evidence-based review of the literature resulted in several nonhormone options for the treatment of vasomotor symptoms.

Recommended: Cognitive-behavioral therapy, clinical hypnosis, selective serotonin reuptake inhibitors/serotonin-norepinephrine reuptake inhibitors, gabapentin, fezolinetant (Level I); oxybutynin (Levels I-II); weight loss, stellate ganglion block (Levels II-III).

Not recommended: Paced respiration (Level I); supplements/herbal remedies (Levels I-II); cooling techniques, avoiding triggers, exercise, yoga, mindfulness-based intervention, relaxation, suvorexant, soy foods and soy extracts, soy metabolite equol, cannabinoids, acupuncture, calibration of neural oscillations (Level II); chiropractic interventions, clonidine; (Levels I-III); dietary modification and pregabalin (Level III)”.

What do the Levels mean in the 2023 Nonhormone Therapy Position Statement of The North American Menopause Society?

On page one in the The 2023 Nonhormone Therapy Position Statement of The North American Menopause Society: Abstract – Methods the NAMS elaborate on:

Methods: The panel assessed the most current and available literature to determine whether to recommend or not recommend use based on these levels of evidence:

  • Level I, good and consistent scientific evidence
  • Level II, limited or inconsistent scientific evidence
  • Level III, consensus and expert opinion”.

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Last Updated: 26 December 2025 – Last Revised: 26 December 2025