âFurther research and regulation of pharmacy-compounded hormones is needed before they can be recommended for use with menopausal symptomsâ.1
Umbrella
What may the Bioidentical Hormones Umbrella include?
Depending on the Source (DotS) this Umbrella may include:
- Bioequivalent Hormone Therapy
- Bioidentical Hormone Medications
- Bioidentical Hormone Replacement Therapy (BHRT)
- Bioidentical Hormone Therapy (BHT)
- Bioidentical Hormones
- Bioidenticals
- Custom-Compounded Bioidentical Hormone Therapy (C-CHT)
- Custom-Made Bioidentical Hormones
- Custom-Mixed Bioidentical Hormones
- Hormone Therapy Alternatives
- Natural Hormone Therapies
- Pharmacy Compounded Hormones
- âCompoundedâ Bioidentical Hormone Replacement Therapy (cBHRT)
- âRegulatedâ Bioidentical Hormone Replacement Therapy (rBHRT)
Background
What is the background of bioidentical hormones for the treatment of menopause symptoms?
In Bioidentical Custom Compounded Hormone Therapy the Australasian Menopause Society (AMS) explain:
Bioidentical Hormones
What are bioidentical hormones?
DotS the definition of bioidentical hormones may vary. In Menopausal Symptoms: In Depth: What the Science Says About Complementary Approaches for Menopause Symptoms â Other Complementary Approaches: Bioidentical Hormones the (United States) National Center for Complementary and Integrative Healthâs (NCCIH) definition is:
Bioidentical Hormone Therapy
What is bioidentical hormone therapy?
DotS the definition of bioidentical hormone therapy may vary. In Menopause FAQs: Hormone Therapy for Menopause Symptoms â Q. Iâve heard about something called bioidentical hormones. What are they? the North American Menopause Societyâs (NAMS) definition is:
What is FDA?
FDA can be an abbreviation for the (United States) Food and Drug Administration.
Body-Identical Hormone Therapy
What is body-identical hormone therapy?
DotS the definition of body-identical hormone therapy may vary. In Bioidentical Custom Compounded Hormone Therapy the AMSâs definition is:
Compounding
What is compounding?
DotS the definition of compounding may vary. In Compounding and the FDA: Questions and Answers â What Is Compounding? the FDA elaborate on:
Compounded Bioidentical Hormones
What are compounded bioidentical hormones?
DotS the definition of compounded bioidentical hormones may vary. In Complementary and Herbal Therapies for Hot Flushes | New: January 2018: Compounded Bioidentical Menopausal Hormone Therapy the AMS note:
Pharmacy-Compounded Hormones
What are pharmacy-compounded hormones?
In Menopause Management: Pharmacy-Compounded Hormones the (Australian) Jean Hailes for Womenâs Health (JH) definition is:
The hormones are made into capsules, creams, gels, drops applied to the tongue, lozenges or troches (soft square-shaped tablets) sucked in the cheekâ.8
Compounded Bioidentical Hormone Replacement Therapies
What are Compounded Bioidentical Hormone Replacement Therapies (cBHRT)?
In Bioidentical HRT: Part A â Explanation of cBHRT: Licensing In UK â Medicines and Healthcare Products Regulatory Agency (MHRA) the British Menopause Society (BMS) explain:
- Do not follow the same regulatory pathway of evaluation by the MHRA as conventional pharmaceutical products
- Have not been through the rigorous process of drug development which conventional medicines and products such as rBHRT undergo
- Have not been scientifically evaluated in controlled randomised clinical trials for effectiveness and safety against placebo or conventional HRTâ.9
What is UK?
UK can be an abbreviation for the United Kingdom.
cBHRT
What is cBHRT?
DotS the definition of cBHRT may vary. In Bioidentical HRT: Part B â Explanation of rBHRT: Summary of Key Terminologies the BMSâs definition is:
What is MHRA?
MHRA can be an abbreviation for Medicines and Healthcare Products Regulatory Agency in the United Kingdom.
rBHRT
What is rBHRT?
DotS the definition of rBHRT may vary. In Bioidentical HRT: Part B â Explanation of rBHRT: Summary of Key Terminologies the BMSâs definition is:
Custom-Compounded Elephants
What maybe some elephants in the custom-compounded bioidentical hormone therapy room?
In Compounding and the FDA: Questions and Answers â Are Compounded Drugs Approved By FDA? the FDA elaborate on:
In What Is Custom-Compounded Therapy? the NAMS note:
In What Is Custom-Compounded Therapy? the NAMS also note:
Saliva Testing Elephants
What may be some elephants in the saliva testing room?
In What Is Hormone Testing? the NAMS explain:
In What Is Hormone Testing? the NAMS also note:
Products
What are two kinds of bioidentical hormone products?
In Menopausal Symptoms: In Depth: What the Science Says About Complementary Approaches for Menopause Symptoms â Other Complementary Approaches: Bioidentical Hormones the NCCIH elaborate on:
Natural or Not
Are bioidentical hormones natural?
In Bioidentical Custom Compounded Hormone Therapy the AMS explain:
In what country is the TGA?
Australia.
Safer or Not
Are bioidentical hormones safer than HT?
Depending on the compounder, seller, company or other, the answer to the question âAre bioidentical hormones safe?â may vary.
In Bioidentical Hormones: Are They Safer? Are bioidentical or natural hormones safer and more effective than hormones used in traditional hormone therapy for menopause symptoms? a (United States) Mayo Clinic author explains:
On page one in Bioidentical Hormone Therapy: Custom-Compounded Versus Government Approved â Bioidentical Custom-Compounded Hormones the NAMS elaborate on:
In Bioidentical Custom Compounded Hormone Therapy: Safety Concerns About Compounded Bioidentical Hormones the AMS elaborate on their concerns about:
- âRisk of endometrial hyperplasia and neoplasia
- Quality Control and contaminentsâ.21
In Menopause Management: Pharmacy-Compounded Hormones some of the JHâs âquestions about the safety and effectiveness of pharmacy-compounded hormonesâ, include:
- âWe have no research evidence that the recommended doses of the hormone preparations made by compounding pharmacists are safe or effective
- It has been claimed this form of hormone therapy does not cause side effects, but this therapy is similar to all prescription hormone therapies, and therefore should have the same risks and benefits. This is unproven and unlikely, with many women presenting with known complications of oestrogen and testosterone therapy while on compounded hormonal preparationsâ.22
North America
What does the NAMS note about bioidentical hormones for menopause symptoms?
In Bioidentical Hormone Therapy: Custom Compounded versus Government Approved dated 2020, the NAMS elaborate on:
Australia
What does the JH note about pharmaceutically produced MHT products in Australia?
In Menopause Management: Pharmacy-Compounded Hormones the JH notes:
2016 Revised Global Consensus Statement
What is one of the points of consensus about custom-compounded hormone therapy?
One of the points of consensus in the Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT â endorsed by seven menopause-related organizations â published online 20 June 2016, is:
- âThe use of custom-compounded hormone therapy is not recommended because of lack of regulation, rigorous safety and efficacy testing, batch standardization, and purity measuresâ.25
2019 BMS Consensus Statement
What are the aims of the BMS Consensus Statement Bioidentical HRT reviewed in October 2019?
In Bioidentical HRT: Introduction the British Menopause Society (BMS) explain:
- Differences between custom âcompoundedâ bioidentical hormone replacement therapy (cBHRT) and conventionally prescribed âregulatedâ bioidentical hormone replacement therapy (rBHRT)
- Issues which have caused confusion regarding the regulation and prescribing of these hormones
- Scientific rationale for the potential advantages of regulated bioidentical hormone replacement therapy (rBHRT) compared to other types of conventional HRTâ.26
2020 NASEM Study
What was the conclusion of the (United States) National Academies of Science, Engineering, and Medicine (NASEM) Study on the Clinical Utility of Treating Patients with Compounded âBioidenticalâ Hormone Therapy?
In National Academies of Science, Engineering, and Medicine (NASEM) Study on the Clinical Utility of Treating Patients with Compounded âBioidenticalâ Hormone Therapy provided to the (United States) Food and Drug Administration (FDA) on 01 July 2020, the study leads explain:
Health Care Provider
What if I choose to use bioidentical hormones?
If you choose to use bioidentical hormones it may be in your best interest to also choose to tell your health care providers you are doing this. The JH caution:
Health Topics A-Z
Where may I find Health Topics related to Bioidentical Hormones?
In Health Topics A-Z you may find:
Links
Where may I find Links related to Bioidentical Hormones?
Your Country may have Links similar to:
Links
This Links List to third party websites is neither comprehensive nor exhaustive. Inclusion on this Links List does not imply endorsement or recommendation. Non-inclusion on this Links List does not imply non-endorsement or non-recommendation. Third party websites are not under the control of Meno Martha International Menopause Directory. Third party websites may contain explicit medical images and/or sexual references. Please read Meno Martha International Menopause Directoryâs Links Policy before proceeding to a Link. Please contact Webmaster if you experience a problem with a Link.- 5 of the Most Common Questions About Menopause
- 9 Myths and Misunderstandings About Menopausal Hormone Therapy (MHT): 7. Myth â Compounded Bioidentical Hormone Therapy Is Safer Than Conventional MHT
- Bijuva Launched for Moderate To Severe Hot Flashes In Menopause
- Bioidentical Custom Compounded Hormone Therapy
- Bioidentical HRT [British Menopause Society Consensus Statement]
Bioidentical Hormone Preparations â History of Development
- Bioidentical Hormone Therapy
- Bioidentical Hormone Therapy: Custom Compounded versus Government Approved
- Bioidentical Hormones
- Bioidentical Hormones Explained â A British Menopause Society Video
- Bioidentical Hormones â Ask Dr Jean
- Bioidentical Hormones â Risks Revisited
- Bioidentical Hormones: Are They Safer?
- Bioridiculous
- Complementary Medicine Options for Menopausal Symptoms
- Complementary and Herbal Therapies for Hot Flushes: Compounded Bioidentical Menopausal Hormone Therapy
- Complementary/Alternative Therapies for Menopausal Women
- Compounded Bioidentical Hormone Therapy
- Compounded Bioidentical Hormone Therapy [Video]
- Compounded Bioidentical Hormones In Endocrinology Practice: An Endocrine Society Scientific Statement
- Compounding Interests: The Risks of Bioidentical Hormones
- Compounding Research
- Compounding and the FDA: Questions and Answers
- Custom-Compounded Bioidentical HT for Menopause Symptoms May Yield âAbnormally Highâ Hormone Levels
- Deciding About Hormone Therapy
- Despite Effectiveness Women Remain Skeptical of Hormones At MenopauseâWhatâs the Problem?
- Early Menopause: Experiences and Perspectives of Women and Health Practitioners â Womenâs Profiles
- Endocrine Society Encourages Clinicians To Avoid Prescribing Compounded Hormones
- FDA Approves Intrarosa for Postmenopausal Women Experiencing Pain During Sex
- Fact Sheets and Downloads: Additional Downloadable Resources â Vaginal Estrogen Therapy
- Follicle-Stimulating Hormone (FSH) Levels Test
- HRT and Alternatives
- HRT: Summary
- Hormone Help Desk: ET, EPT, and More: Bioidentical Hormone Therapy (BHT)
- Hormone Replacement Therapy (HRT) Explained â A British Menopause Society Video
- Hormone Replacement Therapy (HRT): Alternatives
- Hot Flashes: Manage Without Medication?
- Hot Flashes: What Can I Do?
- Index To Drug-Specific Information [United States]
- Information About Menopause [Multiply Languages] [Videos]
- Is It Really âFDA Approved?â FDA Doesnât Approve Compounded Drugs
- Lifestyle and Behaviour Changes for Menopausal Symptoms
- Lifestyle and Behavioural Modifications for Menopausal Symptoms
- Luteinizing Hormone (LH) Levels Test
- Menopause
- Menopause
- Menopause
- Menopause & Herbs
- Menopause FAQs: Hormone Therapy for Menopause Symptoms â Q. Iâve heard about something called bioidentical hormones. What are they?
- Menopause FAQs: Hot Flashes
- Menopause Hormone Therapy: Who Shouldnât Take It?
- Menopause In the New Millennium
- Menopause Management: Pharmacy-Compounded Hormones
- Menopause Symptoms and Relief
- Menopause Treatment
- Menopause What Are the Symptoms?
- Menopause â Complementary Therapies [Multiply Languages] [Video]
- Menopause â Is Menopausal Hormone Therapy (HRT) Safe? [Multiply Languages] [Video]
- Menopause â What Is Menopausal Hormone Therapy (HRT)? [Multiply Languages] [Video]
- Menopause: Complementary Therapies for Menopausal Symptoms [Video Interview Stories]
- Menopause: Diagnosis & Treatment
- Menopause: Diagnosis and Management â Information for the Public: Questions To Ask About Menopause â Treatment for Menopausal Symptoms [NICE Guideline]
- Menopause: Hormone Replacement Therapy (HRT) [Video Interview Stories]
- Menopause: Medicines To Help You
- Menopause: Menopause â Hormone Treatments
- Menopause: Non-Hormonal Treatment & Relief for Hot Flashes
- NAMS Applauds NASEM Efforts on Compounded Bioidentical Hormone Therapy
- National Academies of Science, Engineering, and Medicine (NASEM) Study on the Clinical Utility of Treating Patients With Compounded âBioidenticalâ Hormone Therapy
- National Center for Complementary and Integrative Health: 4 Things To Know About Menopausal Symptoms and Complementary Health Practices
- National Center for Complementary and Integrative Health: Herbs At A Glance
- National Center for Complementary and Integrative Health: How Safe Is This Product or Practice?
- National Center for Complementary and Integrative Health: Know the Science: How Medications and Supplements Can Interact
- National Center for Complementary and Integrative Health: Menopausal Symptoms: In Depth: What the Science Says About Complementary Health Approaches for Menopausal Symptoms â Other Complementary Approaches: Bioidentical Hormone
- National Center for Complementary and Integrative Health: Natural Doesnât Necessarily Mean Safer, or Better
- Natural Therapies & Supplements
- Neither Natural Nor Safe: Compounded Bioidentical Hormones Need Better Evidence
- Non-Hormonal Treatment Options for Menopausal Symptoms
- NonHormonal Treatments for Menopausal Symptoms
- Office of Dietary Supplements: Black Cohosh
- Office of Dietary Supplements: Dietary Supplement Fact Sheets
- Revised Global Consensus Statement on Menopausal Hormone Therapy
- Statement on Improving Adverse Event Reporting of Compounded Drugs To Protect Patients
- The Clinical Utility of Compounded Bioidentical Hormone Therapy: A Review of Safety, Effectiveness, and Use (2020)
- Urogenital Atrophy Explained â A British Menopause Society Video
- Urogenital Problems
- Use of Compounded Hormone Therapy In the United States: Report of The North American Menopause Society Survey
- Vaginal Dryness
- Vaginal Dryness
- Vaginal Dryness Alternative Treatments
- Video Series-2018 â Nonhormone Prescription Options for Hot Flashes
- Video Series-2018 â The Truth About Nonpharmacologic Options for Hot Flushes
- Video Series-2020 â How To Talk To Your Primary Care Clinician About Your Overall Health
- Video Series-2020 â TSECsâA New Treatment for Hot Flashes and Night Sweats
- Video Series-2020 â What You Need To Know About Bioidentical Hormone Therapy
- Video Series-2021 â What Women Need To Know About Hormone Therapies
- What Is Custom-Compounded Therapy?
- What Is Hormone Testing?
- What Is Menopausal Hormone Therapy (MHT) and Is It Safe?
- What You Need To Know About Dietary Supplements
Sources
Where may I find the Sources quoted?
You may find the Sources quoted at:
Sources
- Menopause Management: Pharmacy-Compounded Hormones. Last Updated: 07 December 2020 | Last Reviewed: 17 December 2017. Jean Hailes for Womenâs Health https://jeanhailes.org.au/health-a-z/menopause/menopause-management/ Accessed: 03 January 2021
- Bioidentical Custom Compounded Hormone Therapy. Content Updated: May 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/212-bioidentical-hormones-for-menopausal-symptoms Accessed: 03 January 2021
- Menopausal Symptoms: In Depth: What the Science Says About Complementary Approaches for Menopause Symptoms â Other Complementary Approaches: Bioidentical Hormones. Last Updated: May 2017. National Center for Complementary and Integrative Health https://www.nccih.nih.gov/health/menopausal-symptoms-in-depth Accessed: 03 January 2021
- Menopause FAQs: Hormone Therapy for Menopause Symptoms â Q. Iâve heard about something called bioidentical hormones. What are they? North American Menopause Society https://www.menopause.org/for-women/menopause-faqs-hormone-therapy-for-menopause-symptoms Accessed: 03 January 2021
- Bioidentical Custom Compounded Hormone Therapy. Content Updated: May 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/212-bioidentical-hormones-for-menopausal-symptoms Accessed: 03 January 2021
- Compounding and the FDA: Questions and Answers â What Is Compounding? Content Current As of: 21 June 2018. Food and Drug Administration https://www.fda.gov/drugs/guidancecomplianceregulatoryinformation/pharmacycompounding/ucm339764.htm Accessed: 03 January 2021
- Bioidentical Custom Compounded Hormone Therapy: Safety Concerns About Compounded Bioidentical Hormones. Content Updated: May 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/212-bioidentical-hormones-for-menopausal-symptoms Accessed: 03 January 2021
- Menopause Management: Pharmacy-Compounded Hormones. Last Updated:Â 07 December 2020 | Last Reviewed: 17 December 2017. Jean Hailes for Womenâs Health https://jeanhailes.org.au/health-a-z/menopause/menopause-management/ Accessed: 03 January 2021
- Bioidentical HRT: Part A â Explanation of cBHRT: Licensing In UK â Medicines and Healthcare Products Regulatory Agency (MHRA). Reviewed: October 2019. British Menopause Society https://thebms.org.uk/publications/consensus-statements/bioidentical-hrt/ Accessed: 03 January 2021
- Bioidentical HRT: Part A â Explanation of cBHRT: Licensing In UK â Medicines and Healthcare Products Regulatory Agency (MHRA). Reviewed: October 2019. British Menopause Society https://thebms.org.uk/publications/consensus-statements/bioidentical-hrt/ Accessed: 03 January 2021
- Bioidentical HRT: Part B â Explanation of rBHRT: Key Terminologies. Reviewed: October 2019. British Menopause Society https://thebms.org.uk/publications/consensus-statements/bioidentical-hrt/ Accessed: 03 January 2021
- Compounding and the FDA: Questions and Answers â Are Compounded Drugs Approved By FDA? Content Current As of: 21 June 2018. Food and Drug Administration https://www.fda.gov/drugs/guidancecomplianceregulatoryinformation/pharmacycompounding/ucm339764.htm Accessed: 03 January 2021
- What Is Custom-Compounded Therapy? North American Menopause Society https://www.menopause.org/publications/clinical-practice-materials/bioidentical-hormone-therapy/what-is-custom-compounded-therapy- Accessed: 03 January 2021
- What Is Custom-Compounded Therapy? North American Menopause Society https://www.menopause.org/publications/clinical-practice-materials/bioidentical-hormone-therapy/what-is-custom-compounded-therapy- Accessed: 03 January 2021
- What Is Hormone Testing? North American Menopause Society https://www.menopause.org/publications/clinical-practice-materials/bioidentical-hormone-therapy/what-is-hormone-testing- Accessed: 03 January 2021
- What Is Hormone Testing? North American Menopause Society https://www.menopause.org/publications/clinical-practice-materials/bioidentical-hormone-therapy/what-is-hormone-testing- Accessed: 03 January 2021
- Menopausal Symptoms: In Depth: What the Science Says About Complementary Approaches for Menopause Symptoms â Other Complementary Approaches: Bioidentical Hormones. Last Updated: May 2017. National Center for Complementary and Integrative Health https://www.nccih.nih.gov/health/menopausal-symptoms-in-depth Accessed: 03 January 2021
- Bioidentical Custom Compounded Hormone Therapy. Content Updated: May 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/212-bioidentical-hormones-for-menopausal-symptoms Accessed: 03 January 2021
- Burnett, T. Bioidentical Hormones: Are They Safer? 03 December 2019. https://www.mayoclinic.org/diseases-conditions/menopause/expert-answers/bioidentical-hormones/faq-20058460 Accessed: 03 January 2021
- Bioidentical Hormone Therapy: Custom-Compounded Versus Government-Approved â Bioidentical Custom-Compounded Hormones. 2020:1. North American Menopause Society https://www.menopause.org/docs/default-source/2015/mn-bioidenticals.pdf Accessed: 03 January 2021
- Bioidentical Custom Compounded Hormone Therapy: Safety Concerns About Compounded Bioidentical Hormones. Content Updated: May 2018. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/212-bioidentical-hormones-for-menopausal-symptoms Accessed: 03 January 2021
- Menopause Management: Pharmacy-Compounded Hormones. Last Updated:Â 07 December 2020 | Last Reviewed: 17 December 2017. Jean Hailes for Womenâs Health https://jeanhailes.org.au/health-a-z/menopause/menopause-management/ Accessed: 03 January 2021
- Bioidentical Hormone Therapy: Custom-Compounded Versus Government-Approved â Bioidentical Custom-Compounded Hormones. 2020:1. North American Menopause Society https://www.menopause.org/docs/default-source/2015/mn-bioidenticals.pdf Accessed: 03 January 2021
- Menopause Management: Pharmacy-Compounded Hormones. Last Updated:Â 07 December 2020 | Last Reviewed: 17 December 2017. Jean Hailes for Womenâs Health https://jeanhailes.org.au/health-a-z/menopause/menopause-management/ Accessed: 03 January 2021
- De Villiers, T. J., Hall, J. E., Pinkerton, J. V., Pérez, S. C., Rees, M., Yang, C, and Pierroz, D. D. Revised Global Consensus Statement on Menopausal Hormone Therapy: Section B: General Principles Governing the Use of MHT. Climacteric, 2016;19:4:314 https://www.imsociety.org/manage/images/pdf/ba6379e868044bec13015ac2b84f2753.pdf Accessed: 03 January 2021
- Bioidentical HRT: Introduction. Reviewed: October 2019. British Menopause Society https://thebms.org.uk/publications/consensus-statements/bioidentical-hrt/ Accessed: 03 January 2021
- National Academies of Science, Engineering, and Medicine (NASEM) Study on the Clinical Utility of Treating Patients with Compounded âBioidenticalâ Hormone Therapy. 02 July 2020. National Academies of Science, Engineering, and Medicine https://www.fda.gov/drugs/human-drug-compounding/national-academies-science-engineering-and-medicine-nasem-study-clinical-utility-treating-patients Accessed: 03 January 2021
- Menopause Management: Pharmacy-Compounded Hormones. Last Updated: 07 December 2020 | Last Reviewed: 17 December 2017. Jean Hailes for Womenâs Health https://jeanhailes.org.au/health-a-z/menopause/menopause-management/ Accessed: 03 January 2021