“Genitourinary syndrome of menopause is caused by
a decrease in estrogen production. Less estrogen
makes your vaginal tissues thinner, drier, less elastic…”.1

Umbrella

What may the Genitourinary Syndrome of Menopause Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Atrophic Vaginitis
  • Genital Atrophy
  • Genitourinary/Genito-Urinary Syndrome of Menopause (GSM)
  • Menopause Vaginal Dryness
  • Urogenital Problems
  • Vaginal Atrophy
  • Vaginal Dryness
  • Vaginal Symptoms
  • Vulvovaginal Atrophy (VVA)

Definition

What is the genitourinary syndrome of menopause (GSM)?

DotS the definition of GSM may vary. On page one in Genitourinary Syndrome of Menopause, published May 2025, the (United States) Menopause Society’s (formerly the North American Menopause Society) definition is:

“The genitourinary syndrome of menopause (GSM) includes bothersome vaginal, vulvar (lips of the vagina), and urinary symptoms that can affect quality of life, sexual satisfaction, and even your relationship with your partner. Unlike hot flashes, which typically improve with time, GSM usually worsens over time without treatment”.2

Common or Not

How common is GSM in postmenopausal women?

In Symptoms of Menopause: Bladder, Vaginal and Vulval Problems the (Australian) Jean Hailes for Women’s Health (JH) explain:

“As you move into perimenopause and menopause, low oestrogen levels change your vulval, vaginal and bladder tissues. These changes may affect up to half of postmenopausal women”.3

Symptoms

What may be symptoms of GSM?

In Vaginal Atrophy: Symptoms & Causes – Symptoms the (United States) Mayo Clinic explain:

“Genitourinary syndrome of menopause (GSM) signs and symptoms may include:

  • Vaginal dryness
  • Vaginal burning
  • Vaginal discharge
  • Genital itching
  • Burning with urination
  • Urgency with urination
  • Frequent urination
  • Recurrent urinary tract infections
  • Urinary incontinence
  • Light bleeding after intercourse
  • Discomfort with intercourse
  • Decreased vaginal lubrication during sexual activity
  • Shortening and tightening of the vaginal canal”.4

Cause

What causes GSM?

In Vaginal Atrophy: Symptoms & Causes – Causes the Mayo Clinic elaborate on:

“Genitourinary syndrome of menopause is caused by a decrease in estrogen production. Less estrogen makes your vaginal tissues thinner, drier, less elastic and more fragile”.5

Common or Not

How common is GSM?

In Genitourinary Syndrome of Menopause: Key Points the Australasian Menopause Society note:

  • “These symptoms are common- affecting between 40% and 90% of menopausal women. Urinary incontinence develops in up to 50% of postmenopausal women”.6

Treatment

What are some GSM treatments?

On page one and two in Genitourinary Syndrome of Menopause the Menopause Society elaborate on:

“There are many effective treatment options for GSM, including over-the-counter and prescription therapies. Therapies for less severe symptoms include nonhormone over-the-counter lubricants used as needed for sexual activity and moisturizers used regularly (several times per week) to maintain moisture. Prescription therapies include low-dose vaginal estrogens, vaginal dehydroepiandrosterone inserts, and oral ospemifene. Nonhormone lubricants and moisturizers can be used in combination with prescription therapies for more severe symptoms.

  • “Nonhormone Remedies
    • Vaginal Lubricants…
    • Vaginal Moisturizers…
    • Regular Sexual Stimulation…
    • Expanding Your Views of Sexual Pleasure…
    • Vaginal Dilators…
    • Pelvic Floor Exercises…
  • Vaginal Hormone Therapy…
    • An effective and safe treatment, low-dose local estrogen applied directly to the vagina…
    • FDA-approved low-dose vaginal estrogen products…
    • Dehydroepiandrosterone (DHEA; Prasterone)
    • Low-dose vaginal estrogen or DHEA may be options for women with a history breast or uterine cancer…
  • Systemic Estrogen Therapy
  • Other Therapies…
    • Ospemifene
    • Vaginal Laser Therapy…”.7

Painful Intercourse

How may painful intercourse be resolved?

The Mayo Clinic explain:

“… make an appointment to see your doctor if you experience painful intercourse that’s not resolved by using a vaginal moisturizer (K-Y Liquibeads, Replens, Sliquid, others) or water-based lubricant (Astroglide, K-Y Jelly, Sliquid, others)”.8

Vaginal Estrogen

Is vaginal estrogen placed directly into the vagina?

On page one in Deciding About Hormone Therapy Use, published February 2025, the Menopause Society explain:

“If you are bothered only by vaginal dryness, you can use very low doses of estrogen placed directly into the vagina. These low doses generally do not raise blood estrogen levels above postmenopause levels and do not treat hot flashes. You do not need to take a progestogen when using only low doses of estrogen in the vagina”.9

Genitourinary Syndrome of Menopause: AUA/SUFU/AUGS Guideline (2025)

What is the Genitourinary Syndrome of Menopause: AUA/SUFU/AUGS Guideline (2025), published April 2025, endorsed by The International Society for the Study of Women’s Sexual Health (ISSWSH) and The Menopause Society (TMS)?

In Genitourinary Syndrome of Menopause: AUA/SUFU/AUGS Guideline (2025) the authors elaborate on:

“This guideline provides information to clinicians regarding identification, diagnosis, counseling, and treatment for patients with GSM to optimize symptom control and quality of life while minimizing adverse events. The strategies defined in this document were derived from evidence-based and consensus-based processes; however, shared decision-making is the optimal strategy to individualize level of impact and ultimate interventions”.10

What is AUA, SUFU and AUGS?

In the context above, these abbreviations stand for the:

Health Care Provider

What if I think I have GSM?

If you think you have GSM it is important to talk to your health care provider. In The 2023 Practitioner’s Toolkit for Managing Menopause – Effectiveness: Local Treatment of Urogenital Atrophy, published online 01 December 2023, the authors note:

“Urogenital symptoms due to estrogen insufficiency are under-recognized and under-treated. These symptoms can be effectively treated with an array of local therapies including intravaginal estrogen preparations or DHEA (prasterone) and intravaginal moisturizers. Concurrent progestogen therapy is not required. Many women require local therapy, in addition to systemic MHT, to relieve urogenital symptoms. It is important patients understand that treatment needs to be ongoing and is not simply a short course of therapy”.11

In Symptoms of Menopause: Bladder, Vaginal and Vulval Problems – Urinary Symptoms the JH explain:

“While symptoms such as hot flushes usually disappear over time, bladder, vaginal and vulval problems can persist and may even get worse. But many treatments are available, so ask your doctor for recommendations”.12

Health Topics A-Z

Where may I find Health Topics A-Z related to Genitourinary Syndrome of Menopause?

In Health Topics A-Z you may find:

Links

Where may I find Links related to Genitourinary Syndrome of Menopause?

Your Country may have Links similar to:

Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Vaginal Atrophy: Symptoms & Causes – Causes. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/symptoms-causes/syc-20352288 Accessed: 02 August 2025
  2. Genitourinary Syndrome of Menopause. 2025:1. Menopause Society https://menopause.org/wp-content/uploads/for-women/MenoNote-GSM.pdf Accessed: 02 August 2025
  3. Symptoms of Menopause: Bladder, Vaginal and Vulval Problems. Last Updated: 06 May 2025. Last Reviewed: 23 April 2025. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-symptoms/ Accessed: 02 August 2025
  4. Vaginal Atrophy: Symptoms & Causes – Symptoms. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/symptoms-causes/syc-20352288 Accessed: 02 August 2025
  5. Vaginal Atrophy: Symptoms & Causes – Causes. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/symptoms-causes/syc-20352288 Accessed: 02 August 2025
  6. Genitourinary Syndrome of Menopause: Key Points. Content Created October 2024. Australasian Menopause Society https://www.menopause.org.au/hp/information-sheets/genitourinary-syndrome-of-menopause
  7. Genitourinary Syndrome of Menopause. 2025: 1-2. Menopause Society https://menopause.org/wp-content/uploads/for-women/MenoNote-GSM.pdf Accessed: 02 August 2025
  8. Vaginal Atrophy: Symptoms & Causes – Symptoms: When To See A Doctor. 17 September 2021. Mayo Clinic https://www.mayoclinic.org/diseases-conditions/vaginal-atrophy/symptoms-causes/syc-20352288 Accessed: 02 August 2025
  9. Deciding About Hormone Therapy Use. 2025:1. Menopause Society https://menopause.org/wp-content/uploads/default-document-library/MenoNote-Deciding-About-HT-2025.pdf Accessed: 02 August 2025
  10. Genitourinary Syndrome of Menopause: AUA/SUFU/AUGS Guideline (2025). April 2025. American Urological Association https://www.auanet.org/guidelines-and-quality/guidelines/genitourinary-syndrome-of-menopause Accessed: 02 August 2025
  11. Davis, S. R., Taylor, S., Hemachandra, C., Magraith, K., Ebeling, P. R., Jane, F., and Islam12 September 2024, R. M. The 2023 Practitioner’s Toolkit for Managing Menopause: The 2023 Practitioner’s Toolkit for Managing the Menopause Supporting Notes – Effectiveness: Local Treatment of Urogenital Atrophy. Published Online: 30 October 2023 https://www.tandfonline.com/doi/full/10.1080/13697137.2023.2258783 Accessed: 02 August 2025
  12. Symptoms of Menopause: Bladder, Vaginal and Vulval Problems – Urinary Symptoms. Last Updated: 06 May 2025. Last Reviewed: 23 April 2025. Jean Hailes for Women’s Health https://www.jeanhailes.org.au/health-a-z/menopause/menopause-symptoms/ Accessed: 02 August 2025
Topic Last Updated: 19 August 2025 – Topic Last Reviewed: 02 August 2025