Any association between hormone therapy (HT), hormone replacement therapy (HRT) or menopausal hormone therapy (MHT) and breast cancer risk can be important for women who would like to choose to use HT.

In Research on Hormone Replacement Therapy and Breast Cancer Risk (Last Modified on: 10 November 2017), the (United States) Breastcancer.org elaborate on:

Meno Martha, Hormone Therapy and Breast Cancer Risk

“Numerous studies have looked at the potential health benefits and risks of hormone replacement therapy — particularly the increased risk of breast cancer. However, it’s hard to compare their results and make sense of them all together, because these studies often differ in key ways: the type of estrogen/progestogen used; the duration of use; the dosage; the age at which participating women started HRT; and other health characteristics of participants. For the medical community, piecing it all together is like taking puzzle pieces from different boxes and trying to form them into a picture that makes sense. Also, when you see a news report about HRT, it’s usually based on the conclusions of the latest study, rather than the body of research as a whole. That can make things even more confusing”.

In Menopause Management: Menopausal Hormone Therapy (MHT) – Breast Cancer & MHT (Last Updated 19 Meno Martha, Hormone Therapy and Breast Cancer RiskFebruary 2019 — Last Reviewed 17 December 2018), the (Australasian) Jean Hailes for Women’s Health (JH) elaborate on:

“For otherwise healthy women, taking MHT for 2-5 years to relieve menopausal symptoms causes little if any increase in breast cancer risk”.

Meno Martha, Hormone Therapy and Breast Cancer RiskMeno Martha, Hormone Therapy and Breast Cancer RiskIn Does Hormone Replacement Therapy Increase Cancer Risk? Does HRT Increase the Risk of Breast Cancer?, Last Reviewed: 27 February 2019, the Cancer Research UK (United Kingdom) elaborate on:

“The risk of breast cancer increases for postmenopausal women using any type of HRT. But it is biggest for those using combined HRT, which has the hormones oestrogen and progestogen. Risk is also higher in those who used HRT for more than 5 years. But when HRT is stopped, risk of breast cancer will start to drop back down. It takes about 4 years for the risk to go down to the same level as those who have not used HRT”.

Meno Martha, Hormone Therapy and Breast Cancer RiskIn the April 2018 video Hormones and Breast Cancer the North American Menopause Society explain:

“In this latest video, Hormones and Breast Cancer, Dr. Shapiro interviews Dr. Stephanie Faubion, Director, Office of Women’s Health at the Mayo Clinic in Rochester, Minnesota. Dr. Faubion addresses the concerns women may have about the risks associated with estrogens and breast cancer. She also emphasizes the importance of having this conversation with your clinician”.

Meno Martha, Hormone Therapy and Breast Cancer RiskIn HRT: Benefits and Risks – In Summary (Reviewed: November 2017), the (British) Women’s Health Concern elaborate on:

“Women wishing to start HRT should carefully discuss the benefits and risks of treatment with their doctor to see what is right for them, taking into account their age, medical history, risk factors and personal preferences”.

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Last Updated: 31 May 2020 – Last Revised: 23 April 2018
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