“Talk with a health care professional about whether the use of hormone therapy to prevent chronic conditions is right for you. And consider scientific…”.1

Umbrella
What may the Hormone Therapy 2012 Update for Chronic Conditions Umbrella include?

Depending on the Source (DotS) this Umbrella may include:

  • Chronic Conditions/Diseases/Illnesses
  • Hormone Replacement Therapy (HRT)
  • Hormone Therapy (HT)
  • Hormone Therapy and Cancer
  • Hormone Therapy and Dementia
  • Hormone Therapy and Heart Disease and Stroke (Cardiovascular Disease)
  • Hormone Therapy and Osteoporosis
  • Menopausal Hormone Therapy (MHT)
  • Postmenopause Chronic Conditions/Diseases/Illnesses Prevention

Date

What can it be important to be clear about with hormone therapy (HT) information?

I think it can be important to be clear about the date of all information including the date of HT information, because this information may have been updated.

Symptoms or Chronic Conditions

What can it also be important to be clear about with HT information?

I think it can also be important to be clear about whether HT information is about the use of HT for the management of menopausal symptoms such as hot flushes, night sweats and vaginal dryness; or for the prevention of chronic conditions such as cardiovascular disease, cancer and osteoporosis.

Background

What is the background for the (United States) U.S. Preventative Services Task Force’s Recommendations on Menopausal Hormone Therapy?

In Final Recommendations on Menopausal Hormone Therapy for the Primary Prevention of Chronic Condition published in 2012, the Task Force explain:

“Today, many women live for 30 years or more after they go through menopause. As they get older, their risk of common chronic conditions increases. These chronic conditions include heart disease, breast cancer, fractures, and dementia (problems with thinking and memory). There is much interest and research in finding ways to prevent these chronic conditions”.2

The Task Force also note:

Hormone Therapy 2012 Update for Chronic Conditions

“Some research initially suggested that continuing hormone pills for the long term, after menopausal symptoms have ended, might reduce the risk of some important common chronic conditions. However, more recent and larger studies, including a very large study of many thousands of women, found that this is not true for most of these chronic conditions. In fact, using hormone therapy to prevent chronic conditions can increase the risk of some of these conditions”.3

Review

What did the Task Force review?

The Task Force explain:

“The Task Force reviewed recent research studies on the use of hormone therapy to prevent chronic conditions”.4

Prevention

Who are the Task Force’s recommendations for?

According to the Task Force:

“These recommendations are for women who have already gone through menopause and are thinking about hormone therapy as a way to prevent chronic conditions (illnesses that last a long time)”.5

The Task Force also note:

“The recommendations don’t apply to women who are interested in hormone therapy to manage the symptoms of menopause, such as hot flashes. They also don’t apply to women younger than age 50 who have had a hysterectomy (surgery to remove the uterus) that resulted in menopause”.6

Recommendations

What were the Task Force’s recommendations?

The Task Force explain:

  1. “The Task Force recommends against the use of combined estrogen and progestin for the prevention of chronic conditions in postmenopausal women. Grade D.
  2. The Task Force recommends against the use of estrogen for the prevention of chronic conditions in postmenopausal women who have had a hysterectomy. Grade D”.7

What is Grade D?

The Task Force’s Grade D is:

“Not Recommended”.8

What did the Task Force also note?

The Task Force also note:

“These recommendations summarize what the Task Force learned: The harms of hormone therapy, when used to prevent chronic conditions, outweigh the benefits”.9

Review

Are the Task Force’s 2012 recommendations to be reviewed?

Yes. On 12 December 2017 the Task Force released its updated recommendations.

In Final Recommendation Statement: Hormone Therapy for the Primary Prevention of Chronic Conditions In Postmenopausal Women dated 12 November 2017, the Task Force explain:

“The U.S. Preventive Services Task Force released today a final recommendation statement on hormone therapy for the primary prevention of chronic conditions in postmenopausal women. The Task Force recommends against hormone therapy for preventing chronic conditions in women who have gone through menopause, as the benefits do not outweigh the harms”.10

Health Care Provider

What if I choose to use HT to prevent chronic conditions?

If you choose to use HT to prevent chronic conditions, it may be in your best interest to also choose to talk to your health care provider about this. The Task Force explain when:

“Making a decision about using hormone therapy to prevent chronic conditions: Think about your own health and lifestyle. Consider your personal beliefs and preferences for health care. Talk with a health care professional about whether the use of hormone therapy to prevent chronic conditions is right for you. And consider scientific recommendations, like this one from the Task Force”.11

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Sources

Where may I find the Sources quoted?

You may find the Sources quoted at:

Sources

  1. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: Should You Use Hormone Therapy To Prevent Chronic Conditions? Making A Decision About Using Hormone Therapy To Prevent Chronic Conditions. October 2012:3. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
  2. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: Hormone Therapy To Prevent Chronic Conditions. October 2012:1. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
  3. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions:  Hormone Therapy To Prevent Chronic Conditions. October 2012:1. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
  4. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: Hormone Therapy To Prevent Chronic Conditions. October 2012:1. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
  5. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: Hormone Therapy To Prevent Chronic Conditions. October 2012:1. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
  6. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: Hormone Therapy To Prevent Chronic Conditions. October 2012:1. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
  7. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: The Final Recommendations on Hormone Therapy To Prevent Chronic Conditions: What Do They Mean? October 2012:3. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
  8. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: What Is the U.S. Preventative Services Task Force? USPSTF Recommendation Grades. October 2012:4. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
  9. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions. October 2012:1. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
  10. Final Recommendation Statement: Hormone Therapy for the Primary Prevention of Chronic Conditions In Postmenopausal Women. 12 December 2017. Current As of September 2019. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/Announcements/News/Item/final-recommendation-statement-hormone-therapy-for-the-primary-prevention-of-chronic-conditions-in-postmenopausal-women Accessed: 21 March 2020
  11. Archived: Menopausal Hormone Therapy: Preventative Medication – Archived: Related Information for Consumers: Menopausal Hormone Therapy To Prevent Conditions: Consumer Guide – Menopausal Hormone Therapy for the Primary Prevention of Chronic Conditions: Should You Use Hormone Therapy To Prevent Chronic Conditions? Making A Decision About Using Hormone Therapy To Prevent Chronic Conditions. October 2012:3. U.S. Preventative Services Task Force https://www.uspreventiveservicestaskforce.org/uspstf12/menohrt/menohrtfact.pdf Accessed: 21 March 2020
Topic Last Updated: 21 March 2020 – Topic Last Reviewed: 21 March 2020
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