Have you been prescribed antidepressants to treat hot flushes or hot flashes even though you do not feel depressed? Antidepressants can be another treatment option for hot flushes.

Antidepressants for Hot Flushes

Can antidepressants be prescribed to treat hot flushes or hot flashes?

On page two in Menopause Management Options: Non-Hormonal Options – Antidepressants the (Australian) Jean Hailes for Women’s Health (JH) explain:

“Some antidepressants have been shown to relieve hot flushes. For example, venlafaxine, paroxetine, escitalopram and fluoxetine. Side effects may include nausea, dry mouth, hot flushes, sweats and insomnia.

Note: Paroxetine and fluoxetine can reduce the effectiveness of some cancer treatment medications”.

In Hot Flashes: Diagnosis & Treatment – Treatment: Antidepressants the (United States) Mayo Clinic elaborate on:

Antidepressants for Hot Flushes“A low-dose form of paroxetine (Brisdelle) is the only nonhormone treatment for hot flashes approved by the U.S. Food and Drug Administration. Other antidepressants that have been used to treat hot flashes include:

  • Venlafaxine (Effexor XR)
  • Paroxetine (Paxil, Pexeva)
  • Citalopram (Celexa)
  • Escitalopram (Lexapro)

These medications aren’t as effective as hormone therapy for severe hot flashes, but they can be helpful to women who can’t use hormones. Possible side effects include nausea, difficulty sleeping or drowsiness, weight gain, dry mouth or sexual dysfunction”.

Hot Flushes + Depression

Do antidepressants used to help manage hot flushes also treat depression?

In Hot Flashes: What Can I Do? Non-Hormonal Medications To Treat Hot Flashes the (United States) National Institute on Aging note:

“Women who use an antidepressant to help manage hot flashes generally take a lower dose than people who use the medication to treat depression”.

Health Care Provider

What if I would like to try an antidepressant to treat my hot flushes or hot flashes?

In Hot Flashes: What Can I Do? Non-Hormonal Medications To Treat Hot Flashes the (United States) National Institute of Aging explain:

Antidepressants for Hot Flushes“As with any medication, talk with your doctor about whether this is the right medication for you and how you might manage any possible side effects”.

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Last Updated: 05 October 2023 – Last Revised: 05 October 2023